A Phase I Study of Everolimus and Bendamustine in Patients With Relapsed/Refractory Lymphoid Hematologic Malignancies

Rasmus T. Hoeg; Julian Davis; Brian A. Jonas; Joseph Tuscano; Aaron Rosenberg; Mehrdad Abedi

doi:10.1016/j.clml.2020.02.006

A Phase I Study of Everolimus and Bendamustine in Patients With Relapsed/Refractory Lymphoid Hematologic Malignancies

Rasmus T. Hoeg, Julian Davis, Brian A. Jonas, Joseph Tuscano, Aaron Rosenberg, Mehrdad Abedi

Hematology and Oncology

Research output: Contribution to journal › Article

Abstract

This is the first study to examine the combination of everolimus and bendamustine in the treatment of lymphoid hematologic malignancies. Eighteen patients with relapsed/refractory lymphoma and multiple myeloma were treated. Toxicities were mainly hematologic. Response rates varied by malignancy from 20% to 100%.

Original language	English (US)
Journal	Clinical Lymphoma, Myeloma and Leukemia
DOIs	https://doi.org/10.1016/j.clml.2020.02.006
State	Accepted/In press - Jan 1 2020

Keywords

Hodgkin lymphoma
Multiple myeloma
Non-Hodgkin lymphoma

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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10.1016/j.clml.2020.02.006

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Hoeg, R. T., Davis, J., Jonas, B. A., Tuscano, J., Rosenberg, A., & Abedi, M. (Accepted/In press). A Phase I Study of Everolimus and Bendamustine in Patients With Relapsed/Refractory Lymphoid Hematologic Malignancies. Clinical Lymphoma, Myeloma and Leukemia. https://doi.org/10.1016/j.clml.2020.02.006

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