A novel route to fully substituted 1H-pyrazoles

Yat Fan Suen, Håkon Hope, Michael H. Nantz, Makhluf J. Haddadin, Mark J. Kurth

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

A novel one-step synthesis route to fully substituted pyrazol-4-ols is reported. This simple yet nonobvious method for the construction of pyrazol-4-ols by the condensation-fragmentation-cyclization-extrusion reactions of thietanones with 1,2,4,5-tetrazines is reported. All of the elements of the thietanone except its sulfur are incorporated in these novel products.

Original languageEnglish (US)
Pages (from-to)8468-8471
Number of pages4
JournalJournal of Organic Chemistry
Volume70
Issue number21
DOIs
StatePublished - Oct 14 2005

ASJC Scopus subject areas

  • Organic Chemistry

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