A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG

Kathryn A. Davis, Beverly Sturges, Charles H. Vite, Vanessa Ruedebusch, Gregory Worrell, Andrew B. Gardner, Kent Leyde, W. Douglas Sheffield, Brian Litt

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

We present results from continuous intracranial electroencephalographic (iEEG) monitoring in 6 dogs with naturally occurring epilepsy, a disorder similar to the human condition in its clinical presentation, epidemiology, electrophysiology and response to therapy. Recordings were obtained using a novel implantable device wirelessly linked to an external, portable real-time processing unit. We demonstrate previously uncharacterized intracranial seizure onset patterns in these animals that are strikingly similar in appearance to human partial onset epilepsy. We propose: (1) canine epilepsy as an appropriate model for testing human antiepileptic devices and new approaches to epilepsy surgery, and (2) this new technology as a versatile platform for evaluating seizures and response to therapy in the natural, ambulatory setting.

Original languageEnglish (US)
Pages (from-to)116-122
Number of pages7
JournalEpilepsy Research
Volume96
Issue number1-2
DOIs
StatePublished - Sep 2011

Fingerprint

Canidae
Epilepsy
Equipment and Supplies
Seizures
Partial Epilepsy
Electrophysiology
Anticonvulsants
Epidemiology
Dogs
Technology
Therapeutics
Electrocorticography

Keywords

  • Canine
  • EEG
  • Epilepsy device
  • Intracranial

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Davis, K. A., Sturges, B., Vite, C. H., Ruedebusch, V., Worrell, G., Gardner, A. B., ... Litt, B. (2011). A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG. Epilepsy Research, 96(1-2), 116-122. https://doi.org/10.1016/j.eplepsyres.2011.05.011

A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG. / Davis, Kathryn A.; Sturges, Beverly; Vite, Charles H.; Ruedebusch, Vanessa; Worrell, Gregory; Gardner, Andrew B.; Leyde, Kent; Sheffield, W. Douglas; Litt, Brian.

In: Epilepsy Research, Vol. 96, No. 1-2, 09.2011, p. 116-122.

Research output: Contribution to journalArticle

Davis, KA, Sturges, B, Vite, CH, Ruedebusch, V, Worrell, G, Gardner, AB, Leyde, K, Sheffield, WD & Litt, B 2011, 'A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG', Epilepsy Research, vol. 96, no. 1-2, pp. 116-122. https://doi.org/10.1016/j.eplepsyres.2011.05.011
Davis, Kathryn A. ; Sturges, Beverly ; Vite, Charles H. ; Ruedebusch, Vanessa ; Worrell, Gregory ; Gardner, Andrew B. ; Leyde, Kent ; Sheffield, W. Douglas ; Litt, Brian. / A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG. In: Epilepsy Research. 2011 ; Vol. 96, No. 1-2. pp. 116-122.
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