A new therapeutic target for myelofibrosis is cause for Gli

Brian Jonas

doi:10.1126/scitranslmed.aan4297

A new therapeutic target for myelofibrosis is cause for Gli

Brian Jonas

Hematology and Oncology

Research output: Contribution to journal › Review article

Abstract

Myeloproliferative neoplasm cells recruit Gli1 positive mesenchymal stromal cells to transdifferentiate into fibrosis-causing myofibroblasts, a process that can be inhibited by a Gli inhibitor.

Original language	English (US)
Article number	aan4297
Journal	Science Translational Medicine
Volume	9
Issue number	392
DOIs	https://doi.org/10.1126/scitranslmed.aan4297
State	Published - May 31 2017

ASJC Scopus subject areas

Medicine(all)

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10.1126/scitranslmed.aan4297

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Jonas, B. (2017). A new therapeutic target for myelofibrosis is cause for Gli. Science Translational Medicine, 9(392), [aan4297]. https://doi.org/10.1126/scitranslmed.aan4297

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