A new high frequency destruction/reperfusion system

Chih Kuang Yeh, Dustin E. Kruse, Michele C Lim, Daniel E. Redline, Katherine W. Ferrara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations


In order to improve the resolution of contrast-assisted imaging systems, we have created a high frequency destruction/reperfusion imaging system with a spatial resolution of 160 by 160 μm. The system utilizes a 1 MHz cylindrically focused transducer for destruction and a 25 MHz spherically focused transducer for pulse/echo imaging. Using a new estimation technique, flow constants proportional to absolute flow rate were estimated from B-mode time-intensity curves. The in vitro results indicate a correlation between the actual flow velocity and the estimated rate constant. In vivo images are presented showing blood perfusion in the ciliary processes and iris of the rabbit eye. Potential applications of this system include high-resolution perfusion assessment in small animals.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Ultrasonics Symposium
EditorsD.E. Yuhas, S.C. Schneider
Number of pages4
StatePublished - 2003
Event2003 IEEE Ultrasonics Symposium - Proceedings - Honolulu, HI, United States
Duration: Oct 5 2003Oct 8 2003


Other2003 IEEE Ultrasonics Symposium - Proceedings
Country/TerritoryUnited States
CityHonolulu, HI

ASJC Scopus subject areas

  • Engineering(all)


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