A new class of nonionic detergents with a gluconamide polar group

Leonard M Hjelmeland, Werner A. Klee, James C. Osborne

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Detergents containing either a cholic acid, a deoxycholic acid, or an octanoic acid-like hydrophobic moiety and a bisgluconamidopropyl polar group were synthesized. Extinction coefficients, partial specific volumes, critical micelle concentrations, and aggregation numbers were determined for each of the detergents. The two bile acid derivatives are capable of solubilizing functional opiate receptor, while the octanoic acid derivative is not.

Original languageEnglish (US)
Pages (from-to)485-490
Number of pages6
JournalAnalytical Biochemistry
Issue number2
StatePublished - Apr 15 1983
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology


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