Abstract
By tethering allyl sulfone to polystyrene (3-steps from polystyrene beads consisting of lithiation, sulfination, and allylation), trisubstituted olefins can be generated by Cα-sulfone alkylation and subsequent resin cleavage by S(N)2' nucleophilic displacement of sulfinate.
Original language | English (US) |
---|---|
Pages (from-to) | 7709-7712 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 38 |
Issue number | 44 |
DOIs | |
State | Published - Nov 3 1997 |
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery