Abstract
Background: Urinary tract infection (UTI) in trauma patients is associated with increased mortality. Whether the urinalysis (UA) is an adequate test for a urinary source of fever in the ICU trauma patient has not been demonstrated. We hypothesized that the UA is a valuable screen for UTI in the febrile, critically ill trauma patient. Study Design: All trauma ICU patients in our surgical ICU who had a fever (temperature >38.0 C), urinary catheter, UA, and a urine culture between January 1, 2011 and December 13, 2011 were reviewed. A positive UA was defined as positive leukocyte esterase, positive nitrite, WBC > 10/high power field, or presence of bacteria. A positive urine culture was defined as growth of ≥105 colony forming units (cfu) of an organism irrespective of the UA result or ≥103 cfu in the setting of a positive UA. A UTI was defined as positive urine culture without an alternative cause of the fever. Results: There were 232 UAs from 112 patients that met criteria. The majority (75%) of patients were men; the mean age was 40 (±16) years. Of the 232 UAs, 90 (38.7%) were positive. There were 14 UTIs. The sensitivity, specificity, positive predictive value, and negative predictive value of the UA for UTI were 100%, 65.1%, 15.5%, and 100%, respectively. Conclusions: A negative UA reliably excludes a catheter-associated UTI in the febrile, trauma ICU patient with a 100% negative predictive value, and it can rapidly direct the clinician toward more likely sources of fever and reduce unnecessary urine cultures.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 162-166 |
| Number of pages | 5 |
| Journal | Journal of the American College of Surgeons |
| Volume | 217 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1 2013 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
Cite this
A negative urinalysis rules out catheter-associated urinary tract infection in trauma patients in the intensive care unit. / Stovall, Robert T.; Haenal, James B.; Jenkins, Timothy C.; Jurkovich, Gregory; Pieracci, Fredric M.; Biffl, Walter L.; Barnett, Carlton C.; Johnson, Jeffrey L.; Bensard, Denis D.; Moore, Ernest E.; Cothren Burlew, Clay.
In: Journal of the American College of Surgeons, Vol. 217, No. 1, 01.07.2013, p. 162-166.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A negative urinalysis rules out catheter-associated urinary tract infection in trauma patients in the intensive care unit
AU - Stovall, Robert T.
AU - Haenal, James B.
AU - Jenkins, Timothy C.
AU - Jurkovich, Gregory
AU - Pieracci, Fredric M.
AU - Biffl, Walter L.
AU - Barnett, Carlton C.
AU - Johnson, Jeffrey L.
AU - Bensard, Denis D.
AU - Moore, Ernest E.
AU - Cothren Burlew, Clay
PY - 2013/7/1
Y1 - 2013/7/1
N2 - Background: Urinary tract infection (UTI) in trauma patients is associated with increased mortality. Whether the urinalysis (UA) is an adequate test for a urinary source of fever in the ICU trauma patient has not been demonstrated. We hypothesized that the UA is a valuable screen for UTI in the febrile, critically ill trauma patient. Study Design: All trauma ICU patients in our surgical ICU who had a fever (temperature >38.0 C), urinary catheter, UA, and a urine culture between January 1, 2011 and December 13, 2011 were reviewed. A positive UA was defined as positive leukocyte esterase, positive nitrite, WBC > 10/high power field, or presence of bacteria. A positive urine culture was defined as growth of ≥105 colony forming units (cfu) of an organism irrespective of the UA result or ≥103 cfu in the setting of a positive UA. A UTI was defined as positive urine culture without an alternative cause of the fever. Results: There were 232 UAs from 112 patients that met criteria. The majority (75%) of patients were men; the mean age was 40 (±16) years. Of the 232 UAs, 90 (38.7%) were positive. There were 14 UTIs. The sensitivity, specificity, positive predictive value, and negative predictive value of the UA for UTI were 100%, 65.1%, 15.5%, and 100%, respectively. Conclusions: A negative UA reliably excludes a catheter-associated UTI in the febrile, trauma ICU patient with a 100% negative predictive value, and it can rapidly direct the clinician toward more likely sources of fever and reduce unnecessary urine cultures.
AB - Background: Urinary tract infection (UTI) in trauma patients is associated with increased mortality. Whether the urinalysis (UA) is an adequate test for a urinary source of fever in the ICU trauma patient has not been demonstrated. We hypothesized that the UA is a valuable screen for UTI in the febrile, critically ill trauma patient. Study Design: All trauma ICU patients in our surgical ICU who had a fever (temperature >38.0 C), urinary catheter, UA, and a urine culture between January 1, 2011 and December 13, 2011 were reviewed. A positive UA was defined as positive leukocyte esterase, positive nitrite, WBC > 10/high power field, or presence of bacteria. A positive urine culture was defined as growth of ≥105 colony forming units (cfu) of an organism irrespective of the UA result or ≥103 cfu in the setting of a positive UA. A UTI was defined as positive urine culture without an alternative cause of the fever. Results: There were 232 UAs from 112 patients that met criteria. The majority (75%) of patients were men; the mean age was 40 (±16) years. Of the 232 UAs, 90 (38.7%) were positive. There were 14 UTIs. The sensitivity, specificity, positive predictive value, and negative predictive value of the UA for UTI were 100%, 65.1%, 15.5%, and 100%, respectively. Conclusions: A negative UA reliably excludes a catheter-associated UTI in the febrile, trauma ICU patient with a 100% negative predictive value, and it can rapidly direct the clinician toward more likely sources of fever and reduce unnecessary urine cultures.
UR - http://www.scopus.com/inward/record.url?scp=84879556325&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84879556325&partnerID=8YFLogxK
U2 - 10.1016/j.jamcollsurg.2013.02.030
DO - 10.1016/j.jamcollsurg.2013.02.030
M3 - Article
C2 - 23639202
AN - SCOPUS:84879556325
VL - 217
SP - 162
EP - 166
JO - Journal of the American College of Surgeons
JF - Journal of the American College of Surgeons
SN - 1072-7515
IS - 1
ER -