A multistate outbreak of Escherichia coli O157: H7 infection linked to consumption of beef tacos at a fast-food restaurant chain

Michele T Jay-Russell, Valerie Garrett, Janet C. Mohle-Boetani, Myra Barros, Jeff A. Farrar, Richard Rios, Sharon Abbott, Rick Sowadsky, Ken Komatsu, Robert Mandrell, Jeremy Sobel, S. Benson Werner

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

We investigated a multistate outbreak of Escherichia coli O157:H7 infections. Isolates from 13 case patients from California, Nevada, and Arizona were matched by pulsed-field gel electrophoresis subtyping. Five case patients (38%) were hospitalized, and 3 (23%) developed hemolytic uremic syndrome; none died. The median age was 12 years (range, 2-75 years), and 10 (77%) were female. Case-control studies found an association between illness and eating beef tacos at a national Mexican-style fast-food restaurant chain (88% of cases versus 38% of controls; matched OR, undefined; 95% confidence interval, 1.49 to infinity; P = .009). A traceback investigation implicated an upstream supplier of beef, but a farm investigation was not possible. This outbreak illustrates the value of employing hospital laboratory-based surveillance to detect local clusters of infections and the effectiveness of using molecular subtyping to identify geographically dispersed outbreaks. The outbreak investigation also highlights the need for a more efficient tracking system for food products.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalClinical Infectious Diseases
Volume39
Issue number1
DOIs
StatePublished - Jul 1 2004

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Fast Foods
Restaurants
Escherichia coli O157
Food Chain
Disease Outbreaks
Infection
Hospital Laboratories
Hemolytic-Uremic Syndrome
Pulsed Field Gel Electrophoresis
Case-Control Studies
Eating
Confidence Intervals
Food
Red Meat

ASJC Scopus subject areas

  • Immunology

Cite this

Jay-Russell, M. T., Garrett, V., Mohle-Boetani, J. C., Barros, M., Farrar, J. A., Rios, R., ... Werner, S. B. (2004). A multistate outbreak of Escherichia coli O157: H7 infection linked to consumption of beef tacos at a fast-food restaurant chain. Clinical Infectious Diseases, 39(1), 1-7. https://doi.org/10.1086/421088

A multistate outbreak of Escherichia coli O157 : H7 infection linked to consumption of beef tacos at a fast-food restaurant chain. / Jay-Russell, Michele T; Garrett, Valerie; Mohle-Boetani, Janet C.; Barros, Myra; Farrar, Jeff A.; Rios, Richard; Abbott, Sharon; Sowadsky, Rick; Komatsu, Ken; Mandrell, Robert; Sobel, Jeremy; Werner, S. Benson.

In: Clinical Infectious Diseases, Vol. 39, No. 1, 01.07.2004, p. 1-7.

Research output: Contribution to journalArticle

Jay-Russell, MT, Garrett, V, Mohle-Boetani, JC, Barros, M, Farrar, JA, Rios, R, Abbott, S, Sowadsky, R, Komatsu, K, Mandrell, R, Sobel, J & Werner, SB 2004, 'A multistate outbreak of Escherichia coli O157: H7 infection linked to consumption of beef tacos at a fast-food restaurant chain', Clinical Infectious Diseases, vol. 39, no. 1, pp. 1-7. https://doi.org/10.1086/421088
Jay-Russell, Michele T ; Garrett, Valerie ; Mohle-Boetani, Janet C. ; Barros, Myra ; Farrar, Jeff A. ; Rios, Richard ; Abbott, Sharon ; Sowadsky, Rick ; Komatsu, Ken ; Mandrell, Robert ; Sobel, Jeremy ; Werner, S. Benson. / A multistate outbreak of Escherichia coli O157 : H7 infection linked to consumption of beef tacos at a fast-food restaurant chain. In: Clinical Infectious Diseases. 2004 ; Vol. 39, No. 1. pp. 1-7.
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