A microbial perspective of human developmental biology

Mark R. Charbonneau, Laura V. Blanton, Daniel B. Digiulio, David A. Relman, Carlito B Lebrilla, David A. Mills, Jeffrey I. Gordon

Research output: Contribution to journalReview article

93 Scopus citations

Abstract

When most people think of human development, they tend to consider only human cells and organs. Yet there is another facet that involves human-associated microbial communities. A microbial perspective of human development provides opportunities to refine our definitions of healthy prenatal and postnatal growth and to develop innovative strategies for disease prevention and treatment. Given the dramatic changes in lifestyles and disease patterns that are occurring with globalization, we issue a call for the establishment of 'human microbial observatories' designed to examine microbial community development in birth cohorts representing populations with diverse anthropological characteristics, including those undergoing rapid change.

Original languageEnglish (US)
Pages (from-to)48-55
Number of pages8
JournalNature
Volume535
Issue number7610
DOIs
StatePublished - Jul 6 2016

ASJC Scopus subject areas

  • Medicine(all)
  • General

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    Charbonneau, M. R., Blanton, L. V., Digiulio, D. B., Relman, D. A., Lebrilla, C. B., Mills, D. A., & Gordon, J. I. (2016). A microbial perspective of human developmental biology. Nature, 535(7610), 48-55. https://doi.org/10.1038/nature18845