A linkage map of mouse chromosome 8: Further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19

Thad A. Howard, Julie M. Rochelle, Ann M. Saunders, Michael F Seldin

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Using an interspecific cross, a mouse chromosome 8 linkage map spanning 72 cM has been defined by the segregation of restriction fragment length variants. Linkage and genetic distance were established for 10 loci by analysis of 114 meiotic events and indicated the following gene order: (centromere)-Insr-3.5 cM-Plat-26.3 cM-Crryps/Mel/Jund-3.5 cM-Junb/Ucp-10.5 cM-Mt-1-27.2 cM-Acta2-0.9 cM-Aprt. These data provide further definition of mouse chromosome 8 linkage relationships and the relationship between segments of this chromosome and human chromosomes 8, 16, and 19.

Original languageEnglish (US)
Pages (from-to)207-213
Number of pages7
JournalGenomics
Volume10
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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