A fluoroscopy-based computed tomography scanner for small specimen research

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12 Scopus citations


RATIONALE AND OBJECTIVES. A small-laboratory computed tomography (CT) system using a fluoroscopic system and a personal computer was fabricated and tested. The motivation for building this specimen scanner was to provide medical researchers with the capability of using CT as a practical tool in their research, as well as to provide an opportunity for hands-on CT instruction. METHODS AND MATERIALS. The CT system was constructed using mostly off-the-shelf items; however, the CT stage itself was custom fabricated and software development was necessary. In addition, a personal computer and a standard fluoroscopy system were used. RESULTS. The spatial resolution was found to match the 228-μm sampling limitation, yielding approximately 2 line pairs per mm. Iodine contrast sensitivity studies showed that 1% solution of 370 mg/ml iodine solution was easily detected (P = .05). CONCLUSIONS. A small CT scanner for specimen research can be economically constructed, and is capable of good performance. The authors found substantial interest on the part of small animal researchers involved in a wide variety of medical research.

Original languageEnglish (US)
Pages (from-to)539-544
Number of pages6
JournalInvestigative Radiology
Issue number6
StatePublished - 1993


  • animal research
  • Computed tomography
  • digital imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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