A fast, reciprocal pathway between the lateral geniculate nucleus and visual cortex in the macaque monkey

Farran Briggs, William Martin Usrey

Research output: Contribution to journalArticle

51 Scopus citations

Abstract

Neurons in the lateral geniculate nucleus (LGN) not only provide feedforward input to primary visual cortex (V1), but also receive robust feedback from the cortex. Accordingly, visual processing in the LGN is continuously influenced by previous patterns of activity. This study examines the temporal properties of feedforward and feedback pathways between the LGN and V1 in the macaque monkey to provide a lower bound on how quickly the cortex can influence the LGN. In so doing, we identified a subclass of corticogeniculate neurons that receives direct, suprathreshold input from the LGN that is similar in latency to that directed to other recipient neurons (4.2±0.4 vs 4.0±0.2 ms). These neurons also provide feedback to the LGN that is significantly shorter in latency than that supplied by corticogeniculate neurons lacking LGN input (5.1±1.3 vs 11.1±2.3 ms, respectively). Across our sample of corticogeniculate neurons, the shortest combined visual response latency and feedback latency was 37 ms (mean, 52.5±3.8 ms), indicating that visual signals can rapidly travel from the periphery to the cortex and back to the LGN.

Original languageEnglish (US)
Pages (from-to)5431-5436
Number of pages6
JournalJournal of Neuroscience
Volume27
Issue number20
DOIs
StatePublished - May 16 2007

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Keywords

  • Corticogeniculate
  • LGN
  • Primate
  • Temporal
  • V1
  • Vision

ASJC Scopus subject areas

  • Neuroscience(all)

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