A facile synthesis of (tert-alkoxy)amines

Hasan Palandoken, Chris M. Bocian, Michelle R. McCombs, Michael H. Nantz

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Tertiary alcohols react with stoichiometric BF3•Et 2O and N-hydroxyphthalimide to yield N-alkoxyphthalimides. Subsequent hydrazinolyses afford the title compounds.

Original languageEnglish (US)
Pages (from-to)6667-6669
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number39
DOIs
StatePublished - Sep 26 2005

Keywords

  • Alkoxyamine
  • Aminooxy
  • Boron trifluoride
  • Chemoselective
  • N-Hydroxyphthalimide

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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  • Cite this

    Palandoken, H., Bocian, C. M., McCombs, M. R., & Nantz, M. H. (2005). A facile synthesis of (tert-alkoxy)amines. Tetrahedron Letters, 46(39), 6667-6669. https://doi.org/10.1016/j.tetlet.2005.07.149