A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular bis-heterocyclizations

Jeffrey D. Butler, Danielle M. Solano, Lori I. Robins, Makhluf J. Haddadin, Mark J. Kurth

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

(Chemical Equation Presented) The parent 5H-indazolo[3,2-b]benzo[d]-1,3- oxazine heterocycle as well as a series of novel analogues have been synthesized utilizing two subsequent intramolecular heterocyclizations in one pot. A variety of diversity groups were added to explore the scope of this reaction and to provide a number of new compounds for biological screening.

Original languageEnglish (US)
Pages (from-to)234-240
Number of pages7
JournalJournal of Organic Chemistry
Volume73
Issue number1
DOIs
StatePublished - Jan 4 2008

ASJC Scopus subject areas

  • Organic Chemistry

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