A diisopropoxyphosphonate disulfone

Jessica H. Wong, Marilyn M. Olmstead, James C. Fettinger, Jacquelyn Gervay-Hague

Research output: Contribution to journalArticle

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Abstract

The title mol-ecule, diisopropyl (diisopropoxy-phosphoryl-methyl-sulfonyl- methyl-sulfonyl-meth-yl)phospho-nate, C15H34O10P2S2, represents a disulfone of a phosphate ester that has been investigated as a target for chemotherapy. The disulfone has four half-mol-ecules with crystallographic twofold symmetry in the asymmetric unit. The S=O, P=O and P - O bonds average 1.439, 1.472 and 1.567 Å, respectively. Three isopropyl groups are each disordered over two sites, two of them in a 2:1 ratio and the other in a 3:2 ratio.

Original languageEnglish (US)
JournalActa Crystallographica Section E: Structure Reports Online
Volume63
Issue number6
DOIs
StatePublished - May 3 2007

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Chemotherapy
chemotherapy
esters
Esters
phosphates
Phosphates
Drug Therapy
symmetry

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Structural Biology

Cite this

A diisopropoxyphosphonate disulfone. / Wong, Jessica H.; Olmstead, Marilyn M.; Fettinger, James C.; Gervay-Hague, Jacquelyn.

In: Acta Crystallographica Section E: Structure Reports Online, Vol. 63, No. 6, 03.05.2007.

Research output: Contribution to journalArticle

Wong, Jessica H. ; Olmstead, Marilyn M. ; Fettinger, James C. ; Gervay-Hague, Jacquelyn. / A diisopropoxyphosphonate disulfone. In: Acta Crystallographica Section E: Structure Reports Online. 2007 ; Vol. 63, No. 6.
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