A computer-controlled, continuously circulating, hot irrigating system for endometrial ablation

Michael Baggish, Marie Paraiso, E. M. Breznock, Stephen M Griffey

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

OBJECTIVE: This study evaluated the efficacy of a computer-controlled thermal catheter system to ablate the endometrium by use of 5 to 15 ml of hot saline solution. STUDY DESIGN: Five in vivo sheep uteri and 32 freshly excised human uteri were studied by inserting a self-contained heater catheter equipped with thermocouples and circulating hot saline solution for 15 minutes within the uteri at various temperature settings ranging from 60° C to 80° C. The uteri were grossly examined and microscopically evaluated by hematoxylin and eosin and reduced nicotinamide adenine dinucleotide- diaphorase stains for degree of acute destruction, depth of thermal injury, and predicted viability. RESULTS: All 80° C sheep treatments resulted in complete loss of viability at mucosal, submucosal, and myometrial levels. In human uteri temperatures ≥ 80° C produced grossly recognizable thermal damage to the endometrium. Full-thickness irreversible damage was seen in the endometrium. Loss of viability was also demonstrated 1 to 3 mm deep in the superficial myometrium. Intrauterine pressure was demonstrated to range from 20 to 40 mm Hg, with a mean of 26 mm Hg. No leakage of fluid from the oviducts was observed. CONCLUSION: The data presented here demonstrate that a simple technique coupled with a sophisticated monitoring control system could successfully ablate the endometrium without the vagaries associated with individual operator skill levels.

Original languageEnglish (US)
Pages (from-to)1842-1848
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume173
Issue number6
DOIs
StatePublished - 1995

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Keywords

  • continuously circulating hot saline solution
  • Endometrial ablation
  • thermal catheter

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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