A comprehensive review of apples and apple components and their relationship to human health

Dianne A. Hyson

Research output: Contribution to journalArticle

167 Citations (Scopus)

Abstract

There has been an increasing appreciation and understanding of the link between dietary fruit and vegetable intake and improved health in humans. The widespread and growing intake of apples and apple juice/products and their rich phytochemical profile suggest their important potential to affect the health of the populations consuming them. This review summarizes current clinical, in vitro, and in vivo data and builds upon earlier published reports that apple may reduce the risk of chronic disease by various mechanisms, including antioxidant, antiproliferative, and cell signaling effects. Exposure to apples and apple products has been associated with beneficial effects on risk, markers, and etiology of cancer, cardiovascular disease, asthma, and Alzheimer's disease. Recent work suggests that these products may also be associated with improved outcomes related to cognitive decline of normal aging, diabetes, weight management, bone health, pulmonary function, and gastrointestinal protection.

Original languageEnglish (US)
Pages (from-to)408-420
Number of pages13
JournalAdvances in Nutrition
Volume2
Issue number5
DOIs
StatePublished - Sep 2011
Externally publishedYes

Fingerprint

Malus
human health
apples
Health
Podophyllum peltatum
apple juice
lung function
vegetable consumption
asthma
fruit consumption
Phytochemicals
weight control
Alzheimer disease
chronic diseases
Vegetables
phytopharmaceuticals
cardiovascular diseases
diabetes
etiology
Fruit

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Medicine(all)

Cite this

A comprehensive review of apples and apple components and their relationship to human health. / Hyson, Dianne A.

In: Advances in Nutrition, Vol. 2, No. 5, 09.2011, p. 408-420.

Research output: Contribution to journalArticle

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