A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults

Erin A. Doe, Perry Jones, Mary A O'Hara

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Prophylactic administration of an antiemetic is a common procedure for patients undergoing strabismus surgery. Droperidol and ondansetron hydrochloride are commonly used antiemetics. This study compared the rates of postoperative nausea and vomiting (PONV) in adult patients undergoing strabismus surgery with prophylactically administered Droperidol or ondansetron hydrochloride. Methods: A double-masked, randomized, prospective study was conducted comparing droperidol with ondansetron hydrochloride when administered prophylactically to adults undergoing strabismus surgery. Results: Forty-five patients entered the study with a mean age of 30 years. Twenty percent of patients had nausea immediately postoperatively and 37% had nausea before discharge with no significant differences between groups. Overall rate of emesis, time in the recovery room, and time to discharge was not significantly difference between the droperidol and ondansetron hydrochloride group. Conclusion: No real differences in the ability to prevent PONV between the two medications were bound in this study.

Original languageEnglish (US)
Pages (from-to)264-269
Number of pages6
JournalJournal of Pediatric Ophthalmology and Strabismus
Volume35
Issue number5
StatePublished - Sep 1998
Externally publishedYes

Fingerprint

Droperidol
Ondansetron
Strabismus
Postoperative Nausea and Vomiting
Antiemetics
Nausea
Recovery Room
Double-Blind Method
Vomiting
Prospective Studies

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults. / Doe, Erin A.; Jones, Perry; O'Hara, Mary A.

In: Journal of Pediatric Ophthalmology and Strabismus, Vol. 35, No. 5, 09.1998, p. 264-269.

Research output: Contribution to journalArticle

@article{acb028e5e52d43c7ade98931dd883ebc,
title = "A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults",
abstract = "Background: Prophylactic administration of an antiemetic is a common procedure for patients undergoing strabismus surgery. Droperidol and ondansetron hydrochloride are commonly used antiemetics. This study compared the rates of postoperative nausea and vomiting (PONV) in adult patients undergoing strabismus surgery with prophylactically administered Droperidol or ondansetron hydrochloride. Methods: A double-masked, randomized, prospective study was conducted comparing droperidol with ondansetron hydrochloride when administered prophylactically to adults undergoing strabismus surgery. Results: Forty-five patients entered the study with a mean age of 30 years. Twenty percent of patients had nausea immediately postoperatively and 37{\%} had nausea before discharge with no significant differences between groups. Overall rate of emesis, time in the recovery room, and time to discharge was not significantly difference between the droperidol and ondansetron hydrochloride group. Conclusion: No real differences in the ability to prevent PONV between the two medications were bound in this study.",
author = "Doe, {Erin A.} and Perry Jones and O'Hara, {Mary A}",
year = "1998",
month = "9",
language = "English (US)",
volume = "35",
pages = "264--269",
journal = "Journal of Pediatric Ophthalmology and Strabismus",
issn = "0191-3913",
publisher = "Slack Incorporated",
number = "5",

}

TY - JOUR

T1 - A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults

AU - Doe, Erin A.

AU - Jones, Perry

AU - O'Hara, Mary A

PY - 1998/9

Y1 - 1998/9

N2 - Background: Prophylactic administration of an antiemetic is a common procedure for patients undergoing strabismus surgery. Droperidol and ondansetron hydrochloride are commonly used antiemetics. This study compared the rates of postoperative nausea and vomiting (PONV) in adult patients undergoing strabismus surgery with prophylactically administered Droperidol or ondansetron hydrochloride. Methods: A double-masked, randomized, prospective study was conducted comparing droperidol with ondansetron hydrochloride when administered prophylactically to adults undergoing strabismus surgery. Results: Forty-five patients entered the study with a mean age of 30 years. Twenty percent of patients had nausea immediately postoperatively and 37% had nausea before discharge with no significant differences between groups. Overall rate of emesis, time in the recovery room, and time to discharge was not significantly difference between the droperidol and ondansetron hydrochloride group. Conclusion: No real differences in the ability to prevent PONV between the two medications were bound in this study.

AB - Background: Prophylactic administration of an antiemetic is a common procedure for patients undergoing strabismus surgery. Droperidol and ondansetron hydrochloride are commonly used antiemetics. This study compared the rates of postoperative nausea and vomiting (PONV) in adult patients undergoing strabismus surgery with prophylactically administered Droperidol or ondansetron hydrochloride. Methods: A double-masked, randomized, prospective study was conducted comparing droperidol with ondansetron hydrochloride when administered prophylactically to adults undergoing strabismus surgery. Results: Forty-five patients entered the study with a mean age of 30 years. Twenty percent of patients had nausea immediately postoperatively and 37% had nausea before discharge with no significant differences between groups. Overall rate of emesis, time in the recovery room, and time to discharge was not significantly difference between the droperidol and ondansetron hydrochloride group. Conclusion: No real differences in the ability to prevent PONV between the two medications were bound in this study.

UR - http://www.scopus.com/inward/record.url?scp=0031719905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031719905&partnerID=8YFLogxK

M3 - Article

C2 - 9782437

AN - SCOPUS:0031719905

VL - 35

SP - 264

EP - 269

JO - Journal of Pediatric Ophthalmology and Strabismus

JF - Journal of Pediatric Ophthalmology and Strabismus

SN - 0191-3913

IS - 5

ER -