A comparative study and purification of the enzyme xanthine dehydrogenase from wild-type and adenine-resistant strains of Drosophila melanogaster

Kevork Hagopian, E. J. Duke

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

1. 1. Xanthine dehydrogenase was purified from wild-type and adenine-resistant strains of Drosophila melanogaster. 2. 2. The mol. wt, subunit mol. wt, isoelectric point and electrophoretic mobility of the enzyme from the two strains were similar. 3. 3. The enzyme from the resistant strain was more stable during heat treatment (50°C) and overnight dialysis (4°C) than that from the wild-type strain. 4. 4. Kinetic data show an increased catalytic efficiency for the enzyme from the resistant strain.

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume89
Issue number2
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

Fingerprint Dive into the research topics of 'A comparative study and purification of the enzyme xanthine dehydrogenase from wild-type and adenine-resistant strains of Drosophila melanogaster'. Together they form a unique fingerprint.

Cite this