Abstract
We describe a patient with acute nonlymphocytic leukemia in whom assays of glucose-6-phosphate dehydrogenase activity and cytogenetic studies showed the disease to be clonal and karyotypically abnormal on presentation. When the patient entered a chemotherapy-induced complete clinical remission, the marrow progenitors and blood cells had normal morphologic features and a normal karyotype but were still derived from a single clone.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1513-1517 |
| Number of pages | 5 |
| Journal | New England Journal of Medicine |
| Volume | 310 |
| Issue number | 23 |
| State | Published - 1984 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
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Jacobson, R. J., Temple, M. J., Singer, J. W., Raskind, W., Powell, J. S., & Fialkow, P. J. (1984). A clonal complete remission in a patient with acute nonlymphocytic leukemia originating in a multipotent stem cell. New England Journal of Medicine, 310(23), 1513-1517.