We describe a patient with acute nonlymphocytic leukemia in whom assays of glucose-6-phosphate dehydrogenase activity and cytogenetic studies showed the disease to be clonal and karyotypically abnormal on presentation. When the patient entered a chemotherapy-induced complete clinical remission, the marrow progenitors and blood cells had normal morphologic features and a normal karyotype but were still derived from a single clone.
|Original language||English (US)|
|Number of pages||5|
|Journal||New England Journal of Medicine|
|State||Published - 1984|
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