A case-based review of a simplified quantitative approach to acid-base analysis

Katrina Hopper, Steve C. Haskins

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Objective - To present a simplified quantitative approach to acid-base analysis and to demonstrate its clinical utility. Data Sources - Original research articles and textbooks. Data Synthesis - A simplified quantitative approach to acid-base analysis is presented, which is derived from the Fencl-Stewart approach and calculates the magnitude of the effect on the standardized base excess (SBE) of 5 separate variables: (1) a free water effect (marked by sodium concentration), (2) an effect marked by the chloride concentration, (3) an albumin effect, (4) a lactate effect, and (5) a phosphate effect. Six clinical cases with acid-base abnormalities are presented in which the quantitative approach provides information that is not apparent from the traditional approach. Conclusion - This simplified quantitative approach provides a comprehensive evaluation of complex acid-base disorders, identifies individual processes and their relative influence on SBE, and aids in the development of an appropriate therapeutic plan.

Original languageEnglish (US)
Pages (from-to)467-476
Number of pages10
JournalJournal of Veterinary Emergency and Critical Care
Volume18
Issue number5
DOIs
StatePublished - Oct 2008

Keywords

  • Hypoproteinemia
  • Lactic acidosis
  • Metabolic acidosis
  • Metabolic alkalosis

ASJC Scopus subject areas

  • veterinary(all)

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