Abstract
Objective - To present a simplified quantitative approach to acid-base analysis and to demonstrate its clinical utility. Data Sources - Original research articles and textbooks. Data Synthesis - A simplified quantitative approach to acid-base analysis is presented, which is derived from the Fencl-Stewart approach and calculates the magnitude of the effect on the standardized base excess (SBE) of 5 separate variables: (1) a free water effect (marked by sodium concentration), (2) an effect marked by the chloride concentration, (3) an albumin effect, (4) a lactate effect, and (5) a phosphate effect. Six clinical cases with acid-base abnormalities are presented in which the quantitative approach provides information that is not apparent from the traditional approach. Conclusion - This simplified quantitative approach provides a comprehensive evaluation of complex acid-base disorders, identifies individual processes and their relative influence on SBE, and aids in the development of an appropriate therapeutic plan.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 467-476 |
| Number of pages | 10 |
| Journal | Journal of Veterinary Emergency and Critical Care |
| Volume | 18 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2008 |
Keywords
- Hypoproteinemia
- Lactic acidosis
- Metabolic acidosis
- Metabolic alkalosis
ASJC Scopus subject areas
- veterinary(all)