Find Research Outputs

2020

Older Adults With Isolated Rib Fractures Do Not Require Routine Intensive Care Unit Admission

Bowman, J. A., Jurkovich, G., Nishijima, D. & Utter, G. H., Jan 1 2020, In : Journal of Surgical Research. 245, p. 492-499 8 p.

Research output: Contribution to journalArticle

Rib Fractures
Intensive Care Units
Critical Care
Abbreviated Injury Scale
Guidelines
2019

2019: an update from the Editor-in-Chief

Cherry, S. R., Apr 8 2019, In : Physics in medicine and biology. 64, 8, 1 p.

Research output: Contribution to journalArticle

Open Access

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

Le, S. T., Merleev, A. A., Luxardi, G., Shimoda, M., Adamopoulos, I., Tsoi, L. C., Wang, J. Z., Alexanian, C., Raychaudhuri, S. P., Hwang, S. T., Gudjonsson, J., Marusina, A. I. & Maverakis, E. M., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Th17 Cells
Interleukin-17
Transcriptome
Psoriasis
T-Lymphocytes
2 Citations (Scopus)

3D-printed breast phantom for multi-purpose and multi-modality imaging

He, Y., Liu, Y., Dyer, B. A., Boone, J. M., Liu, S., Chen, T., Zheng, F., Zhu, Y., Sun, Y., Rong, Y. & Qiu, J., Jan 1 2019, In : Quantitative Imaging in Medicine and Surgery. 9, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Breast
Calcinosis
Magnetic Resonance Imaging
Quality Control
Technology

9-Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases

Li, W., Santra, A., Yu, H., Slack, T. J., Muthana, M. M., Shi, D., Liu, Y. & Chen, X., Jun 7 2019, In : Journal of Organic Chemistry. 84, 11, p. 6697-6708 12 p.

Research output: Contribution to journalArticle

N-acetylneuraminate lyase
Neuraminidase
N-Acetylneuraminic Acid
Fluorine
Sialic Acids
1 Citation (Scopus)

A 17-gene Panel for Prediction of Adverse Prostate Cancer Pathologic Features: Prospective Clinical Validation and Utility

Eggener, S., Karsh, L. I., Richardson, T., Shindel, A. W., Lu, R., Rosenberg, S., Goldfischer, E., Korman, H., Bennett, J., Newmark, J. & Denes, B. S., Jan 1 2019, In : Urology.

Research output: Contribution to journalArticle

Prostate
Prostatic Neoplasms
Genes
Prostatectomy
Neoplasm Grading

A 51-Year-Old Man With Unresolved Pulmonary Infiltrates Following Streptococcus pneumoniae Pneumonia

Pugashetti, J. V., Adams, J. Y., Zeki, A. & Kuhn, B., Feb 1 2019, In : Chest. 155, 2, p. e47-e50

Research output: Contribution to journalArticle

Streptococcus pneumoniae
Pneumonia
Lung
Levofloxacin
Sinusitis

AAST Critical Care Committee clinical consensus: ECMO, nutrition

Zonies, D., Codner, P., Park, P., Martin, N. D., Lissauer, M., Evans, S., Cocanour, C. S. & Brasel, K., Mar 1 2019, In : Trauma Surgery and Acute Care Open. 4, 1, e000304.

Research output: Contribution to journalArticle

Open Access
Critical Care
Wounds and Injuries
Extracorporeal Membrane Oxygenation
Research
Critical Illness
3 Citations (Scopus)

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal Fluid
Amyloid
Alzheimer Disease
Positron-Emission Tomography
Area Under Curve
1 Citation (Scopus)

A Bump-Hole Approach for Directed RNA Editing

Monteleone, L. R., Matthews, M. M., Palumbo, C. M., Thomas, J. M., Zheng, Y., Chiang, Y., Fisher, A. J. & Beal, P. A., Feb 21 2019, In : Cell Chemical Biology. 26, 2, p. 269-277.e5

Research output: Contribution to journalArticle

RNA Editing
Guide RNA
RNA
Adenosine Deaminase
Oligonucleotides

A Case for n-of-1 Trials - Reply

Kravitz, R. L., Sim, I. & Duan, N., Mar 1 2019, In : JAMA Internal Medicine. 179, 3, 1 p.

Research output: Contribution to journalLetter

Acceptability, Usability, and Effectiveness: A Qualitative Study Evaluating a Pediatric Telemedicine Program

Sauers-Ford, H. S., Hamline, M. Y., Gosdin, M. M., Kair, L., Weinberg, G. M., Marcin, J. P. & Rosenthal, J., Jan 1 2019, In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Telemedicine
Pediatrics
Interviews
Referral and Consultation
Patient Care
1 Citation (Scopus)

Acceptance versus reappraisal: Behavioral, autonomic, and neural effects

Goldin, P. R., Moodie, C. A. & Gross, J. J., Jan 1 2019, (Accepted/In press) In : Cognitive, Affective and Behavioral Neuroscience.

Research output: Contribution to journalArticle

Autonomic Agents
Emotions
Brain
Respiratory Rate
Heart Rate
1 Citation (Scopus)

Access to Dermatological Care with an Innovative Online Model for Psoriasis Management: Results from a Randomized Controlled Trial

Ford, A. R., Gibbons, C. M., Torres, J., Kornmehl, H. A., Singh, S., Young, P. M., Chambers, C., Maverakis, E. M., Dunnick, C. A. & Armstrong, A. W., Jul 1 2019, In : Telemedicine and e-Health. 25, 7, p. 619-627 9 p.

Research output: Contribution to journalArticle

Psoriasis
Randomized Controlled Trials
Health
Appointments and Schedules
Patient-Centered Care
2 Citations (Scopus)

Acinetobacter baumannii OxyR Regulates the Transcriptional Response to Hydrogen Peroxide

Juttukonda, L. J., Green, E. R., Lonergan, Z. R., Heffern, M., Chang, C. J. & Skaar, E. P., Jan 1 2019, In : Infection and Immunity. 87, 1

Research output: Contribution to journalArticle

Acinetobacter baumannii
Hydrogen Peroxide
Infection
Acinetobacter Infections
Lung

A circulating tumor cell-RNA assay for assessment of androgen receptor signaling inhibitor sensitivity in metastatic castration-resistant prostate cancer

Jan, Y. J., Yoon, J., Chen, J. F., Teng, P. C., Yao, N., Cheng, S., Lozano, A., Chu, G. C. Y., Chung, H., Lu, Y. T., Chen, P. J., Wang, J. J., Lee, Y. T., Kim, M., Zhu, Y., Knudsen, B. S., Feng, F. Y., Garraway, I. P., Gao, A. C., Chung, L. W. K. & 4 others, Freeman, M. R., You, S., Tseng, H. R. & Posadas, E. M., Jan 1 2019, In : Theranostics. 9, 10, p. 2812-2826 15 p.

Research output: Contribution to journalArticle

Open Access
Circulating Neoplastic Cells
Castration
Androgen Receptors
Prostatic Neoplasms
RNA
9 Citations (Scopus)

A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections

Kuppermann, N., Dayan, P. S., Levine, D. A., Vitale, M., Tzimenatos, L. S., Tunik, M. G., Saunders, M., Ruddy, R. M., Roosevelt, G., Rogers, A. J., Powell, E. C., Nigrovic, L. E., Muenzer, J., Linakis, J. G., Grisanti, K., Jaffe, D. M., Hoyle, J. D., Greenberg, R., Gattu, R., Cruz, A. T. & 16 others, Crain, E. F., Cohen, D. M., Brayer, A., Borgialli, D., Bonsu, B., Browne, L., Blumberg, S., Bennett, J. E., Atabaki, S. M., Anders, J., Alpern, E. R., Miller, B., Casper, T. C., Dean, J. M., Ramilo, O. & Mahajan, P., Apr 1 2019, In : JAMA Pediatrics. 173, 4, p. 342-351 10 p.

Research output: Contribution to journalArticle

Decision Support Techniques
Bacterial Infections
Fever
Bacteremia
Bacterial Meningitides

A Combination Flap for Repair of Eclabium

Joo, J. S., Petukhova, T. & Eisen, D. B., Feb 1 2019, In : Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 45, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis

Natividad-Diaz, S. L., Browne, S., Jha, A. K., Ma, Z., Hossainy, S., Kurokawa, Y. K., George, S. & Healy, K. E., Feb 1 2019, In : Biomaterials. 194, p. 73-83 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Microfluidics
Endothelial cells
Biocompatible Materials
Stem cells
brain
Health
Brain
health
Aptitude

A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants

Khlif, M. S., Egorova, N., Werden, E., Redolfi, A., Bocardi, M., DeCarli, C., Fletcher, E., Singh, B., Li, Q., Bird, L. & Brodtmann, A., Jan 1 2019, (Accepted/In press) In : NeuroImage: Clinical. 101581.

Research output: Contribution to journalArticle

Healthy Volunteers
Atlases
Stroke
Anatomy
Stroke Volume

A Comparison of Geriatric Hip Fracture Databases

Shelton, T., Hecht, G., Slee, C. & Wolinsky, P. R., Feb 1 2019, In : The Journal of the American Academy of Orthopaedic Surgeons. 27, 3, p. e135-e141

Research output: Contribution to journalArticle

Hip Fractures
Quality Improvement
Geriatrics
Databases
Wounds and Injuries

A comprehensive plasma metabolomics dataset for a cohort of mouse knockouts within the international mouse phenotyping consortium

Barupal, D. K., Zhang, Y., Shen, T., Fan, S., Roberts, B. S., Fitzgerald, P., Wancewicz, B., Valdiviez, L., Wohlgemuth, G., Byram, G., Choy, Y. Y., Haffner, B., Showalter, M. R., Vaniya, A., Bloszies, C. S., Folz, J. S., Kind, T., Flenniken, A. M., McKerlie, C., Nutter, L. M. J. & 2 others, Lloyd, K. C. K. & Fiehn, O., May 1 2019, In : Metabolites. 9, 5, 101.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Knockout Mice
Metabolites
Plasmas
Oxylipins

Acremonium and trichosporon fungal keratoconjunctivitis in a Leopard Gecko (Eublepharis macularius)

Munevar, C., Moore, B. A., Gleeson, M. D., Ozawa, S. M., Murphy, C. J., Paul-Murphy, J. R. & Leonard, B. C., Jan 1 2019, In : Veterinary Ophthalmology.

Research output: Contribution to journalArticle

Eublepharis macularius
Panthera
Trichosporon
Acremonium
Keratoconjunctivitis
1 Citation (Scopus)

Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia

HALT Pan-Leukemia Gene Panel Consortium, Jun 20 2019, In : Blood. 133, 25, p. 2651-2663 13 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Disease Progression
Chemical activation
Patient treatment
Gene encoding

Acute and Midterm Outcomes of Antegrade vs Retrograde Crossing Strategies for Endovascular Treatment of Iliac Artery Chronic Total Occlusions

Kokkinidis, D. G., Foley, T. R., Cotter, R., Hossain, P., Alvandi, B., Jawaid, O., Haider, M. N., Singh, G., Waldo, S. W., Laird, J. R. & Armstrong, E. J., Jun 1 2019, In : Journal of Endovascular Therapy. 26, 3, p. 342-349 8 p.

Research output: Contribution to journalArticle

Iliac Artery
Therapeutics
Extremities
Logistic Models
Odds Ratio

Acute Changes in NADPH Oxidase 4 in Early Post-Traumatic Osteoarthritis

Wegner, A. M., Campos, N. R., Robbins, M. A., Haddad, A. F., Cunningham, H. C., Yik, J. H. N., Christiansen, B. A. & Haudenschild, D. R., Jan 1 2019, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

NADPH Oxidase
Osteoarthritis
Antioxidants
Joints
Inflammation
1 Citation (Scopus)
Cannabis
Acute Coronary Syndrome
Toxicology
Percutaneous Coronary Intervention
Accelerated Idioventricular Rhythm

Acute infection and subsequent subclinical reactivation of herpes simplex virus 2 after vaginal inoculation of rhesus macaques

Lo, M., Zhu, J., Hansen, S. G., Carroll, T., Zuend, C. F., Nöel-Romas, L., Ma, Z. M., Fritts, L., Huang, M. L., Sun, S., Huang, Y., Koelle, D. M., Picker, L. J., Burgener, A., Corey, L. & Miller, C. J., Jan 1 2019, In : Journal of Virology. 93, 2, e01574-18.

Research output: Contribution to journalArticle

Human herpesvirus 2
Asymptomatic Infections
Human Herpesvirus 2
Macaca mulatta
infection

Acute lead arsenate poisoning in beef cattle in Uruguay

Schild, C. O., Giannitti, F., Medeiros, R. M. T., da Silva Silveira, C., Caffarena, R. D., Poppenga, R. H. & Riet-Correa, F., Jan 1 2019, In : Journal of Veterinary Diagnostic Investigation.

Research output: Contribution to journalArticle

lead arsenate
Uruguay
Lead Poisoning
lesions (animal)
beef cattle

Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

Yu-Han, H., Kanke, M., Kurtz, C. L., Cubitt, R., Bunaciu, R. P., Miao, J., Zhou, L., Graham, J. L., Hussain, M. M., Havel, P. J., Biddinger, S., White, P. J. & Sethupathy, P., Jan 1 2019, In : Physiological Genomics. 51, 8, p. 379-389 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Insulin Resistance
Liver
Homeostasis
Type 2 Diabetes Mellitus

Adaptive task difficulty influences neural plasticity and transfer of training

Flegal, K. E., Ragland, J. D. & Ranganath, C., Mar 1 2019, In : NeuroImage. 188, p. 111-121 11 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Short-Term Memory
Episodic Memory
Brain
Hippocampus
12 Citations (Scopus)

A deep learning model to predict a diagnosis of Alzheimer disease by using 18 F-FDG PET of the brain

Ding, Y., Sohn, J. H., Kawczynski, M. G., Trivedi, H., Harnish, R., Jenkins, N. W., Lituiev, D., Copeland, T. P., Aboian, M. S., Aparici, C. M., Behr, S. C., Flavell, R. R., Huang, S. Y., Zalocusky, K. A., Nardo, L., Seo, Y., Hawkins, R. A., Pampaloni, M. H., Hadley, D. & Franc, B. L., Mar 1 2019, In : RADIOLOGY. 290, 3, p. 456-464 9 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Alzheimer Disease
Learning
ROC Curve
Brain

A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Yang, P. C., Purawat, S., Ieong, P. U., Jeng, M. T., DeMarco, K. R., Vorobyov, I., McCulloch, A. D., Altintas, I., Amaro, R. E. & Clancy, C. E., Mar 1 2019, In : PLoS computational biology. 15, 3, p. e1006856

Research output: Contribution to journalArticle

Open Access
Cardiac Electrophysiology
electrophysiology
Kepler
Workflow
Portability

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Syed, A. U., Reddy, G. R., Ghosh, D., Prada, M. P., Nystoriak, M. A., Morotti, S., Grandi, E., Sirish, P., Chiamvimonvat, N., Hell, J. W., Santana, L. F., Xiang, Y. K., Nieves-Cintrón, M. & Navedo, M. F., Jun 4 2019, In : The Journal of clinical investigation. 130

Research output: Contribution to journalArticle

Open Access
Hyperglycemia
Blood Vessels
Cyclic AMP-Dependent Protein Kinases
Muscle Cells
Glucose

A Descriptive Study of Hospital- and Community-acquired Pressure Ulcers/Injuries

Kirkland-Khyn, H., Teleten, O., Joseph, R. & Maguina, P., Feb 1 2019, In : Wound management & prevention. 65, 2, p. 14-19 6 p.

Research output: Contribution to journalArticle

Pressure Ulcer
Wounds and Injuries
Electronic Health Records
Length of Stay

Adherence to human epidermal growth factor receptor-2 testing and adjuvant trastuzumab treatment guidelines in Ontario

Marshall, D. A., Ferrusi, I. L., Trudeau, M., Leighl, N. B., Hoch, J. S., Grazziotin, L. R., Khong, H., Pullenayegum, E. & Earle, C. C., Jan 1 2019, In : Journal of Oncology Pharmacy Practice.

Research output: Contribution to journalArticle

Ontario
Guidelines
Immunohistochemistry
Hormones
Fluorescence In Situ Hybridization

A distinct structural mechanism underlies TRPV1 activation by piperine

Dong, Y., Yin, Y., Vu, S., Yang, F., Yarov-Yarovoy, V., Tian, Y. & Zheng, J., Jan 1 2019, In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

piperine
Chemical activation
S 6
Capsaicin
Piper nigrum
2 Citations (Scopus)

Adjuvant and Salvage Radiation Therapy After Prostatectomy: ASTRO/AUA Guideline Amendment, Executive Summary 2018

Pisansky, T. M., Thompson, I. M., Valicenti, R. K., D'Amico, A. V. & Selvarajah, S., Jul 1 2019, In : Practical Radiation Oncology. 9, 4, p. 208-213 6 p.

Research output: Contribution to journalArticle

Salvage Therapy
Prostatectomy
Radiotherapy
Guidelines
Hormones

Adjuvant and Salvage Radiotherapy after Prostatectomy: ASTRO/AUA Guideline Amendment 2018-2019

Pisansky, T. M., Thompson, I. M., Valicenti, R. K., D'Amico, A. V. & Selvarajah, S., Sep 1 2019, In : The Journal of urology. 202, 3, p. 533-538 6 p.

Research output: Contribution to journalArticle

Open Access
Salvage Therapy
Adjuvant Radiotherapy
Prostatectomy
Prostatic Neoplasms
Guidelines

A dose-ranging, parallel group, split-face, single-blind phase II study of light emitting diode-red light (LED-RL) for skin scarring prevention: Study protocol for a randomized controlled trial

Nguyen, J. K., Weedon, J., Jakus, J., Heilman, E., Isseroff, R. R., Siegel, D. M. & Jagdeo, J., Jul 15 2019, In : Trials. 20, 1, 432.

Research output: Contribution to journalArticle

Open Access
Cicatrix
Randomized Controlled Trials
Light
Skin
Fibrosis

Advanced glycation end product carboxymethyl-lysine and risk of incident peripheral artery disease in older adults: The Cardiovascular Health Study

Garg, P. K., Biggs, M. L., Barzilay, J., Djousse, L., Hirsch, C. H., Ix, J. H., Kizer, J. R., Tracy, R. P., Newman, A. B., Siscovick, D. S. & Mukamal, K. J., Jan 1 2019, In : Diabetes and Vascular Disease Research.

Research output: Contribution to journalLetter

Open Access
Advanced Glycosylation End Products
Peripheral Arterial Disease
Health
Proportional Hazards Models
Coronary Disease

Advances in therapeutic endoscopy

Tejaswi, S. L., Girotra, M., Lima, J. P. & Tabibian, J. H., Jan 1 2019, In : Gastroenterology Research and Practice. 2019, 6253837.

Research output: Contribution to journalEditorial

Open Access
Endoscopy
Therapeutics

Advantages of the net benefit regression framework for trial-based economic evaluations of cancer treatments: An example from the Canadian Cancer Trials Group CO.17 trial

Hoch, J. S., Hay, A., Isaranuwatchai, W., Thavorn, K., Leighl, N. B., Tu, D., Trenaman, L., Dewa, C. S., O'Callaghan, C., Pater, J., Jonker, D., Chen, B. E. & Mittmann, N., Jun 7 2019, In : BMC Cancer. 19, 1, 552.

Research output: Contribution to journalArticle

Open Access
Cost-Benefit Analysis
Neoplasms
Therapeutics
Economics
Clinical Trials
1 Citation (Scopus)

Adverse Childhood Experiences in Medical Students: Implications for Wellness

Sciolla, A. F., Wilkes, M. S. & Griffin, E. J., Aug 15 2019, In : Academic Psychiatry. 43, 4, p. 369-374 6 p.

Research output: Contribution to journalArticle

Open Access
Medical Students
medical student
childhood
Students
experience

Afatinib use in recurrent epithelial ovarian carcinoma

Shepherd-Littlejohn, A. L., Hanft, W. J., Kennedy, V. A. & Alvarez, E. A., Aug 1 2019, In : Gynecologic Oncology Reports. 29, p. 70-72 3 p.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Carcinoma
BIBW 2992

Afatinib With Pembrolizumab for Treatment of Patients With Locally Advanced/Metastatic Squamous Cell Carcinoma of the Lung: The LUX-Lung IO/KEYNOTE 497 Study Protocol

Levy, B., Paz-Ares, L., Bennouna, J., Felip, E., Abreu, D. R., Isla, D., Barlesi, F., Molinier, O., Madelaine, J., Audigier-Valette, C., Kim, S. W., Kim, H. R., Ozguroglu, M., Erman, M., Badin, F. B., Mekhail, T. M., Scheff, R., Chisamore, M. J., Sadrolhefazi, B. & Riess, J., Jan 1 2019, In : Clinical lung cancer.

Research output: Contribution to journalArticle

Open Access
Squamous Cell Carcinoma
Lung
Safety
Epidermal Growth Factor Receptor
Survival

Affiliation and disease risk: social networks mediate gut microbial transmission among rhesus macaques

Balasubramaniam, K. N., Beisner, B., Hubbard, J. A., Vandeleest, J. J., Atwill, E. R. & Mccowan, B., May 1 2019, In : Animal Behaviour. 151, p. 131-143 13 p.

Research output: Contribution to journalArticle

grooming
social networks
social network
Macaca mulatta
intestinal microorganisms

Affinity selection and sequencing

Lam, K., Apr 1 2019, In : Nature Chemical Biology. 15, 4, p. 320-321 2 p.

Research output: Contribution to journalArticle

Libraries
Peptide Library
Peptides
Tandem Mass Spectrometry
Gel Chromatography

A flexible pressure sensor by induced ordered nano cracks filled with multilayer graphene oxide composite film as a conductive fine-wire network for higher sensitivity

Shi, J., Sun, B., Li, H., Xia, K., Zhang, X., Ding, G., Pan, T. & Yang, Z., Feb 4 2019, In : Flexible and Printed Electronics. 4, 1, 015003.

Research output: Contribution to journalArticle

Graphite
Pressure sensors
Composite films
Oxides
Graphene