Find Research Outputs

2020

Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer

Allen, S. A., Datta, S., Sandoval, J., Tomilov, A., Sears, T., Woolard, K., Angelastro, J. M. & Cortopassi, G. A., Jan 2020, In : Mitochondrion. 50, p. 19-24 6 p.

Research output: Contribution to journalArticle

Cetylpyridinium
AMP-Activated Protein Kinases
temozolomide
Glioblastoma
Pharmaceutical Preparations
Killer Whale
Beluga Whale
Bottle-Nosed Dolphin
Delphinapterus leucas
Orcinus orca

Equine fetal genotyping via aspiration of yolk-sac fluid at 22–28 days of gestation

Ripley, A. M., Penedo, M. C. T., Grahn, R. A., Martinez de Andino, E. V., Walbornn, S. R., Serafini, R., Love, C. C. & Hinrichs, K., Jan 15 2020, In : Theriogenology. 142, p. 34-40 7 p.

Research output: Contribution to journalArticle

Yolk Sac
yolk sac
genotyping
mares
Horses

Functional significance of MAIT cells in psoriatic arthritis

Raychaudhuri, S. K., Abria, C., Mitra, A. & Raychaudhuri, S. P., Jan 1 2020, In : Cytokine. 125, 154855.

Research output: Contribution to journalArticle

Psoriatic Arthritis
T-cells
Interleukin-17
Synovial Fluid
Fluids

Immunohistochemistry and In Situ Hybridization in the Developing Chicken Brain

Tucker, R. P., Ishimaru, T. & Gong, Q., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 421-437 17 p. (Methods in Molecular Biology; vol. 2047).

Research output: Chapter in Book/Report/Conference proceedingChapter

In Situ Hybridization
Chickens
Immunohistochemistry
Antibodies
Brain

Older Adults With Isolated Rib Fractures Do Not Require Routine Intensive Care Unit Admission

Bowman, J. A., Jurkovich, G., Nishijima, D. & Utter, G. H., Jan 1 2020, In : Journal of Surgical Research. 245, p. 492-499 8 p.

Research output: Contribution to journalArticle

Rib Fractures
Intensive Care Units
Critical Care
Abbreviated Injury Scale
Guidelines

Optimizing cell encapsulation condition in ECM-Collagen I hydrogels to support 3D neuronal cultures

Lam, D., Enright, H. A., Peters, S. K. G., Moya, M. L., Soscia, D. A., Cadena, J., Alvarado, J. A., Kulp, K. S., Wheeler, E. K. & Fischer, N. O., Jan 1 2020, In : Journal of Neuroscience Methods. 329, 108460.

Research output: Contribution to journalArticle

Open Access
Hydrogels
Collagen
Cell Survival
Gels
Neurons

Toxic effects of fluridone on early developmental stages of Japanese Medaka (Oryzias latipes)

Jin, J., Kurobe, T., Hammock, B. G., Lam, C. H., Lin, L. & Teh, S. J., Jan 15 2020, In : Science of the Total Environment. 700, 134495.

Research output: Contribution to journalArticle

Industrial poisons
Poisons
Polymerase chain reaction
developmental stage
Gene expression
2019

14C-Cobalamin Absorption from Endogenously Labeled Chicken Eggs Assessed in Humans Using Accelerator Mass Spectrometry

Garrod, M. G., Rossow, H. A., Calvert, C. C., Miller, J. W., Green, R., Buchholz, B. A. & Allen, L. H., Sep 8 2019, In : Nutrients. 11, 9

Research output: Contribution to journalArticle

Open Access
chicken eggs
vitamin B12
Vitamin B 12
Eggs
Biological Availability

2019: an update from the Editor-in-Chief

Cherry, S. R., Apr 8 2019, In : Physics in medicine and biology. 64, 8, 1 p.

Research output: Contribution to journalArticle

Open Access

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

Le, S. T., Merleev, A. A., Luxardi, G., Shimoda, M., Adamopoulos, I., Tsoi, L. C., Wang, J. Z., Alexanian, C., Raychaudhuri, S. P., Hwang, S. T., Gudjonsson, J., Marusina, A. I. & Maverakis, E. M., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Th17 Cells
Interleukin-17
Transcriptome
Psoriasis
T-Lymphocytes
3 Citations (Scopus)

3D-printed breast phantom for multi-purpose and multi-modality imaging

He, Y., Liu, Y., Dyer, B. A., Boone, J. M., Liu, S., Chen, T., Zheng, F., Zhu, Y., Sun, Y., Rong, Y. & Qiu, J., Jan 1 2019, In : Quantitative Imaging in Medicine and Surgery. 9, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Breast
Calcinosis
Magnetic Resonance Imaging
Quality Control
Technology

9-Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases

Li, W., Santra, A., Yu, H., Slack, T. J., Muthana, M. M., Shi, D., Liu, Y. & Chen, X., Jun 7 2019, In : Journal of Organic Chemistry. 84, 11, p. 6697-6708 12 p.

Research output: Contribution to journalArticle

N-acetylneuraminate lyase
Neuraminidase
N-Acetylneuraminic Acid
Fluorine
Sialic Acids
2 Citations (Scopus)

A 17-gene Panel for Prediction of Adverse Prostate Cancer Pathologic Features: Prospective Clinical Validation and Utility

Eggener, S., Karsh, L. I., Richardson, T., Shindel, A. W., Lu, R., Rosenberg, S., Goldfischer, E., Korman, H., Bennett, J., Newmark, J. & Denes, B. S., Jan 1 2019, In : Urology.

Research output: Contribution to journalArticle

Prostate
Prostatic Neoplasms
Genes
Prostatectomy
Neoplasm Grading

A 51-Year-Old Man With Unresolved Pulmonary Infiltrates Following Streptococcus pneumoniae Pneumonia

Pugashetti, J. V., Adams, J. Y., Zeki, A. & Kuhn, B., Feb 1 2019, In : Chest. 155, 2, p. e47-e50

Research output: Contribution to journalArticle

Streptococcus pneumoniae
Pneumonia
Lung
Levofloxacin
Sinusitis

AAST Critical Care Committee clinical consensus: ECMO, nutrition

Zonies, D., Codner, P., Park, P., Martin, N. D., Lissauer, M., Evans, S., Cocanour, C. S. & Brasel, K., Mar 1 2019, In : Trauma Surgery and Acute Care Open. 4, 1, e000304.

Research output: Contribution to journalArticle

Open Access
Critical Care
Wounds and Injuries
Extracorporeal Membrane Oxygenation
Research
Critical Illness
3 Citations (Scopus)

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal Fluid
Amyloid
Alzheimer Disease
Positron-Emission Tomography
Area Under Curve

Absorption and Safety of Topically Applied Timolol for Treatment of Chronic Cutaneous Wounds

Gallegos, A. C., Davis, M. J., Tchanque-Fossuo, C. N., West, K., Eisentrout-Melton, A., Peavy, T. R., Dixon, R. W., Patel, R. P., Dahle, S. E. & Isseroff, R. R., Nov 1 2019, In : Advances in Wound Care. 8, 11, p. 538-545 8 p.

Research output: Contribution to journalArticle

Timolol
Glaucoma
Adrenergic Receptors
Catecholamines
Safety
4 Citations (Scopus)

A Bump-Hole Approach for Directed RNA Editing

Monteleone, L. R., Matthews, M. M., Palumbo, C. M., Thomas, J. M., Zheng, Y., Chiang, Y., Fisher, A. J. & Beal, P. A., Feb 21 2019, In : Cell Chemical Biology. 26, 2, p. 269-277.e5

Research output: Contribution to journalArticle

RNA Editing
Guide RNA
RNA
Adenosine Deaminase
Oligonucleotides

A Case for n-of-1 Trials - Reply

Kravitz, R. L., Sim, I. & Duan, N., Mar 1 2019, In : JAMA Internal Medicine. 179, 3, 1 p.

Research output: Contribution to journalLetter

Acceptability, Usability, and Effectiveness: A Qualitative Study Evaluating a Pediatric Telemedicine Program

Sauers-Ford, H. S., Hamline, M. Y., Gosdin, M. M., Kair, L., Weinberg, G. M., Marcin, J. P. & Rosenthal, J., Jan 1 2019, In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Telemedicine
Pediatrics
Interviews
Referral and Consultation
Patient Care
2 Citations (Scopus)

Acceptance versus reappraisal: Behavioral, autonomic, and neural effects

Goldin, P. R., Moodie, C. A. & Gross, J. J., Jan 1 2019, (Accepted/In press) In : Cognitive, Affective and Behavioral Neuroscience.

Research output: Contribution to journalArticle

Autonomic Agents
Emotions
Brain
Respiratory Rate
Heart Rate
2 Citations (Scopus)

Access to Dermatological Care with an Innovative Online Model for Psoriasis Management: Results from a Randomized Controlled Trial

Ford, A. R., Gibbons, C. M., Torres, J., Kornmehl, H. A., Singh, S., Young, P. M., Chambers, C., Maverakis, E. M., Dunnick, C. A. & Armstrong, A. W., Jul 1 2019, In : Telemedicine and e-Health. 25, 7, p. 619-627 9 p.

Research output: Contribution to journalArticle

Psoriasis
Randomized Controlled Trials
Health
Appointments and Schedules
Patient-Centered Care
2 Citations (Scopus)

Acinetobacter baumannii OxyR Regulates the Transcriptional Response to Hydrogen Peroxide

Juttukonda, L. J., Green, E. R., Lonergan, Z. R., Heffern, M., Chang, C. J. & Skaar, E. P., Jan 1 2019, In : Infection and Immunity. 87, 1

Research output: Contribution to journalArticle

Acinetobacter baumannii
Hydrogen Peroxide
Infection
Acinetobacter Infections
Lung
1 Citation (Scopus)

A circulating tumor cell-RNA assay for assessment of androgen receptor signaling inhibitor sensitivity in metastatic castration-resistant prostate cancer

Jan, Y. J., Yoon, J., Chen, J. F., Teng, P. C., Yao, N., Cheng, S., Lozano, A., Chu, G. C. Y., Chung, H., Lu, Y. T., Chen, P. J., Wang, J. J., Lee, Y. T., Kim, M., Zhu, Y., Knudsen, B. S., Feng, F. Y., Garraway, I. P., Gao, A. C., Chung, L. W. K. & 4 others, Freeman, M. R., You, S., Tseng, H. R. & Posadas, E. M., Jan 1 2019, In : Theranostics. 9, 10, p. 2812-2826 15 p.

Research output: Contribution to journalArticle

Open Access
Circulating Neoplastic Cells
Castration
Androgen Receptors
Prostatic Neoplasms
RNA
10 Citations (Scopus)

A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections

Kuppermann, N., Dayan, P. S., Levine, D. A., Vitale, M., Tzimenatos, L. S., Tunik, M. G., Saunders, M., Ruddy, R. M., Roosevelt, G., Rogers, A. J., Powell, E. C., Nigrovic, L. E., Muenzer, J., Linakis, J. G., Grisanti, K., Jaffe, D. M., Hoyle, J. D., Greenberg, R., Gattu, R., Cruz, A. T. & 16 others, Crain, E. F., Cohen, D. M., Brayer, A., Borgialli, D., Bonsu, B., Browne, L., Blumberg, S., Bennett, J. E., Atabaki, S. M., Anders, J., Alpern, E. R., Miller, B., Casper, T. C., Dean, J. M., Ramilo, O. & Mahajan, P., Apr 1 2019, In : JAMA Pediatrics. 173, 4, p. 342-351 10 p.

Research output: Contribution to journalArticle

Decision Support Techniques
Bacterial Infections
Fever
Bacteremia
Bacterial Meningitides

A Combination Flap for Repair of Eclabium

Joo, J. S., Petukhova, T. & Eisen, D. B., Feb 1 2019, In : Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 45, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis

Natividad-Diaz, S. L., Browne, S., Jha, A. K., Ma, Z., Hossainy, S., Kurokawa, Y. K., George, S. & Healy, K. E., Feb 1 2019, In : Biomaterials. 194, p. 73-83 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Microfluidics
Endothelial cells
Biocompatible Materials
Stem cells
brain
Health
Brain
health
Aptitude
1 Citation (Scopus)

A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants

Khlif, M. S., Egorova, N., Werden, E., Redolfi, A., Bocardi, M., DeCarli, C., Fletcher, E., Singh, B., Li, Q., Bird, L. & Brodtmann, A., Jan 1 2019, (Accepted/In press) In : NeuroImage: Clinical. 101581.

Research output: Contribution to journalArticle

Healthy Volunteers
Atlases
Stroke
Anatomy
Stroke Volume

A Comparison of Different Analysis Methods for Reconstructed Survival Data to Inform Cost‑Effectiveness Analysis

Djalalov, S., Beca, J., Ewara, E. M. & Hoch, J. S., Jan 1 2019, (Accepted/In press) In : PharmacoEconomics.

Research output: Contribution to journalArticle

Cost-Benefit Analysis
Survival
Survival Analysis
Switzerland
Individuality

A Comparison of Geriatric Hip Fracture Databases

Shelton, T., Hecht, G., Slee, C. & Wolinsky, P. R., Feb 1 2019, In : The Journal of the American Academy of Orthopaedic Surgeons. 27, 3, p. e135-e141

Research output: Contribution to journalArticle

Hip Fractures
Quality Improvement
Geriatrics
Databases
Wounds and Injuries

A comprehensive plasma metabolomics dataset for a cohort of mouse knockouts within the international mouse phenotyping consortium

Barupal, D. K., Zhang, Y., Shen, T., Fan, S., Roberts, B. S., Fitzgerald, P., Wancewicz, B., Valdiviez, L., Wohlgemuth, G., Byram, G., Choy, Y. Y., Haffner, B., Showalter, M. R., Vaniya, A., Bloszies, C. S., Folz, J. S., Kind, T., Flenniken, A. M., McKerlie, C., Nutter, L. M. J. & 2 others, Lloyd, K. C. K. & Fiehn, O., May 1 2019, In : Metabolites. 9, 5, 101.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Knockout Mice
Metabolites
Plasmas
Oxylipins
2 Citations (Scopus)

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources

Kernik, D. C., Morotti, S., Wu, H. D., Garg, P., Duff, H. J., Kurokawa, J., Jalife, J., Wu, J. C., Grandi, E. & Clancy, C. E., Sep 1 2019, In : Journal of Physiology. 597, 17, p. 4533-4564 32 p.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Information Storage and Retrieval
Cardiac Myocytes
Phenotype
Cardiac Arrhythmias

Acremonium and trichosporon fungal keratoconjunctivitis in a Leopard Gecko (Eublepharis macularius)

Munevar, C., Moore, B. A., Gleeson, M. D., Ozawa, S. M., Murphy, C. J., Paul-Murphy, J. R. & Leonard, B. C., Jan 1 2019, In : Veterinary Ophthalmology.

Research output: Contribution to journalArticle

Eublepharis macularius
Panthera
Trichosporon
Acremonium
Keratoconjunctivitis
1 Citation (Scopus)

Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia

HALT Pan-Leukemia Gene Panel Consortium, Jun 20 2019, In : Blood. 133, 25, p. 2651-2663 13 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Disease Progression
Chemical activation
Patient treatment
Gene encoding

Acute and Midterm Outcomes of Antegrade vs Retrograde Crossing Strategies for Endovascular Treatment of Iliac Artery Chronic Total Occlusions

Kokkinidis, D. G., Foley, T. R., Cotter, R., Hossain, P., Alvandi, B., Jawaid, O., Haider, M. N., Singh, G., Waldo, S. W., Laird, J. R. & Armstrong, E. J., Jun 1 2019, In : Journal of Endovascular Therapy. 26, 3, p. 342-349 8 p.

Research output: Contribution to journalArticle

Iliac Artery
Therapeutics
Extremities
Logistic Models
Odds Ratio

Acute Changes in NADPH Oxidase 4 in Early Post-Traumatic Osteoarthritis

Wegner, A. M., Campos, N. R., Robbins, M. A., Haddad, A. F., Cunningham, H. C., Yik, J. H. N., Christiansen, B. A. & Haudenschild, D. R., Jan 1 2019, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

NADPH Oxidase
Osteoarthritis
Joints
Knee Injuries
Reactive Oxygen Species
1 Citation (Scopus)
Cannabis
Acute Coronary Syndrome
Toxicology
Percutaneous Coronary Intervention
Accelerated Idioventricular Rhythm

Acute infection and subsequent subclinical reactivation of herpes simplex virus 2 after vaginal inoculation of rhesus macaques

Lo, M., Zhu, J., Hansen, S. G., Carroll, T., Zuend, C. F., Nöel-Romas, L., Ma, Z. M., Fritts, L., Huang, M. L., Sun, S., Huang, Y., Koelle, D. M., Picker, L. J., Burgener, A., Corey, L. & Miller, C. J., Jan 1 2019, In : Journal of Virology. 93, 2, e01574-18.

Research output: Contribution to journalArticle

Human herpesvirus 2
Asymptomatic Infections
Human Herpesvirus 2
Macaca mulatta
infection

Acute lead arsenate poisoning in beef cattle in Uruguay

Schild, C. O., Giannitti, F., Medeiros, R. M. T., da Silva Silveira, C., Caffarena, R. D., Poppenga, R. H. & Riet-Correa, F., Jan 1 2019, In : Journal of Veterinary Diagnostic Investigation.

Research output: Contribution to journalArticle

lead arsenate
Uruguay
Lead Poisoning
lesions (animal)
beef cattle

Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

Yu-Han, H., Kanke, M., Kurtz, C. L., Cubitt, R., Bunaciu, R. P., Miao, J., Zhou, L., Graham, J. L., Hussain, M. M., Havel, P. J., Biddinger, S., White, P. J. & Sethupathy, P., Jan 1 2019, In : Physiological Genomics. 51, 8, p. 379-389 11 p.

Research output: Contribution to journalArticle

Insulin Resistance
Liver
MicroRNAs
Type 2 Diabetes Mellitus
Rodentia

Adaptive task difficulty influences neural plasticity and transfer of training

Flegal, K. E., Ragland, J. D. & Ranganath, C., Mar 1 2019, In : NeuroImage. 188, p. 111-121 11 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Short-Term Memory
Episodic Memory
Brain
Hippocampus

Additional Evidence for DDB2 T338M as a Genetic Risk Factor for Ocular Squamous Cell Carcinoma in Horses

Singer-Berk, M. H., Knickelbein, K. E., Lounsberry, Z. T., Crausaz, M., Vig, S., Joshi, N., Britton, M., Settles, M. L., Reilly, C. M., Bentley, E., Nunnery, C., Dwyer, A., Lassaline, M. E. & Bellone, R. R., Jan 1 2019, In : International Journal of Genomics. 2019, 3610965.

Research output: Contribution to journalArticle

Open Access
Horses
Squamous Cell Carcinoma
Alleles
Epithelial Cells
Genetic Loci
20 Citations (Scopus)

A deep learning model to predict a diagnosis of Alzheimer disease by using 18 F-FDG PET of the brain

Ding, Y., Sohn, J. H., Kawczynski, M. G., Trivedi, H., Harnish, R., Jenkins, N. W., Lituiev, D., Copeland, T. P., Aboian, M. S., Aparici, C. M., Behr, S. C., Flavell, R. R., Huang, S. Y., Zalocusky, K. A., Nardo, L., Seo, Y., Hawkins, R. A., Pampaloni, M. H., Hadley, D. & Franc, B. L., Mar 1 2019, In : RADIOLOGY. 290, 3, p. 456-464 9 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Alzheimer Disease
Learning
ROC Curve
Brain

A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Yang, P. C., Purawat, S., Ieong, P. U., Jeng, M. T., DeMarco, K. R., Vorobyov, I., McCulloch, A. D., Altintas, I., Amaro, R. E. & Clancy, C. E., Mar 1 2019, In : PLoS computational biology. 15, 3, p. e1006856

Research output: Contribution to journalArticle

Open Access
Cardiac Electrophysiology
electrophysiology
Kepler
Workflow
Portability

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Syed, A. U., Reddy, G. R., Ghosh, D., Prada, M. P., Nystoriak, M. A., Morotti, S., Grandi, E., Sirish, P., Chiamvimonvat, N., Hell, J. W., Santana, L. F., Xiang, Y. K., Nieves-Cintrón, M. & Navedo, M. F., Jun 4 2019, In : The Journal of clinical investigation. 130

Research output: Contribution to journalArticle

Open Access
Hyperglycemia
Blood Vessels
Cyclic AMP-Dependent Protein Kinases
Muscle Cells
Glucose

A Descriptive Study of Hospital- and Community-acquired Pressure Ulcers/Injuries

Kirkland-Khyn, H., Teleten, O., Joseph, R. & Maguina, P., Feb 1 2019, In : Wound management & prevention. 65, 2, p. 14-19 6 p.

Research output: Contribution to journalArticle

Pressure Ulcer
Wounds and Injuries
Electronic Health Records
Length of Stay

Adherence to human epidermal growth factor receptor-2 testing and adjuvant trastuzumab treatment guidelines in Ontario

Marshall, D. A., Ferrusi, I. L., Trudeau, M., Leighl, N. B., Hoch, J. S., Grazziotin, L. R., Khong, H., Pullenayegum, E. & Earle, C. C., Jan 1 2019, In : Journal of Oncology Pharmacy Practice.

Research output: Contribution to journalArticle

Ontario
Guidelines
Immunohistochemistry
Hormones
Fluorescence In Situ Hybridization

A distinct structural mechanism underlies TRPV1 activation by piperine

Dong, Y., Yin, Y., Vu, S., Yang, F., Yarov-Yarovoy, V., Tian, Y. & Zheng, J., Jan 1 2019, In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

piperine
Chemical activation
S 6
Capsaicin
Piper nigrum