3D PET using a conventional multislice tomograph without septa

Simon R Cherry, M. Dahlbom, E. J. Hoffman

Research output: Contribution to journalArticlepeer-review

132 Scopus citations

Abstract

A conventional multislice positron emission tomography scanner was modified to operate without interplane septa to evaluate its performance in collecting and reconstructing data in a three-dimensional (3D) format, thereby significantly increasing system sensitivity. A 3D filtered backprojection algorithm was implemented and tested, using both computer simulations and phantom measurements. No artifacts were apparent in the test images, although the algorithm was shown to lead to a 11% degradation in transaxial resolution in the outer planes. Following septa removal, sensitivity was found to increase by a factor of 7 with an increase in scatter fraction from 16 to 41%. Axial resolution degraded from 6.9 to 7.7 mm full width at half maximum at the center of the field of view. The maximum count rate without septa was 2.4 x 105 cps, at a concentration of 0.4 μCi/ml, compared with 1.3 x 105 cps at 1.5 μCi/ml with septa. Brain studies were performed with volunteers using 18F-fluorodeoxyglucose, 18F-fluorodopa, and H2 15O to compare noise-equivalent count rates and qualitatively assess image quality over a wide range of imaging conditions.

Original languageEnglish (US)
Pages (from-to)655-668
Number of pages14
JournalJournal of Computer Assisted Tomography
Volume15
Issue number4
StatePublished - 1991

Keywords

  • Emission computed tomography
  • Emission computed tomography, techniques
  • Emission computed tomography, three-dimensional

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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