3D gadolinium-enhanced MR angiography of the carotid arteries

Harry J. Cloft, Kieran J. Murphy, Martin R. Prince, James A Brunberg

Research output: Contribution to journalArticlepeer-review

86 Scopus citations


Purpose: To compare gadolinium-enhanced magnetic resonance angiography (MRA) of the carotid bifurcation with 2D time-of-flight (TOF) MR angiography with regard to image quality and duration of examination. Materials and Methods: Gadolinium contrast was administered intravenously during 3D MR imaging at 1.5 Tesla in 46 patients presenting with suspected carotid occlusive disease. 2D time-of-flight MR angiography of the carotid bifurcation had been performed in each patient prior to gadolinium-enhanced MR angiography. Results: Gadolinium MRA eliminated slice misregistration and in-plane saturation artifacts that occasionally degrades 2D TOF MR angiography. Gadolinium MRA required less than 4 min to image from the aortic arch to the skull base compared to 11 min for 2D TOF with comparable signal- to-noise ratio (SNR). Postprocessing was required to eliminate overlapping venous enhancement. Both techniques had susceptibility related artifactual loss of signal at the skull base and both demonstrated a linear artifact paralleling the long axis of arteries. Conclusion: Gadolinium-enhanced MR angiography is a promising technique for the evaluation of patients with carotid occlusive disease because it rapidly images the carotid arteries from the aortic arch to the skull base and eliminates some of the artifacts that degrade 2D TOF MR angiography.

Original languageEnglish (US)
Pages (from-to)593-600
Number of pages8
JournalMagnetic Resonance Imaging
Issue number6
StatePublished - 1996
Externally publishedYes


  • Arteries, MR
  • Carotid arteries, stenosis or obstruction
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), flow artifact
  • Magnetic resonance (MR), vascular studies

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics


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