1,3-Dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1,3-butadienes: Synthesis of 3-(4,5-dihydroisoxazol-5-yl)pyrroles

Sung Hee Hwang, Mark J. Kurth

Research output: Contribution to journalArticle

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Abstract

Novel heterocyclic compounds containing the 3-(4,5-dihydroisoxazol-5-yl)pyrrole ring system were synthesized in good yields (66-78%) by regioselective 1,3-dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1,3-dienes followed by Barton-Zard pyrrole annulation.

Original languageEnglish (US)
Pages (from-to)53-56
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number1
DOIs
StatePublished - Jan 1 2002

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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