Deduction of Ca2+ current amplitude by the Conus peptide ω-conotoxin-MVIID (ω-CTx-MVIID) was measured in voltage-clamped, goldfish retinal ganglion cells. Effects of depolarizing shifts in holding potential, and sequential applications of ω-CTx-MVIID, ω-CTx-GVIA, and BAY-K-8644, together with effects of Ni2+ and ω-Aga-IIIA, indicate that ω-CTx-MVIID may target Ca2+ channels differing from those termed T, L, N, P, Q and R.
- Retinal ganglion cell
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience
- Drug Discovery