OCULAR HYPERTENSION TREATMENT STUDY (OHTS)

Project: Research project

Description

DESCRIPTION "This is an application from the Department of Ophthalmology at the
University of California, Davis to become a participating Clinical Center
in the Ocular Hypertension Treatment Study (OHTS). The principal and
co-investigators, along with other members of the UC Davis Department of
Ophthalmology, have an established track record participating as clinical
centers in large, multi-center studies. UC Davis participated successfully
as a clinical center in the Cryo-ROP study and has been selected as the
Visual Field Reading Center for both the Optic Neuritis Treatment Trial
(ONTT) and for the Ocular Hypertension Treatment Study (OHTS). During the past several years, the principal and co-investigator have been
involved in several collaborative studies of perimetry and clinical
psychophysics in glaucoma (EY-03424-13). In ongoing and active cooperation
with practitioners in private practice, at the local Veterans
Administration Outpatient Clinic and at a large multi-clinic HMO (Kaiser
Permanente Medical Group), large numbers of ocular hypertensive patients
have been successfully recruited and retained for longitudinal
psychophysical studies. From January 1, 1992 through December 31, 1992, we
have recruited and retained 249 patients for these studies. These patients
were recruited using selection criteria similar to those for the OHTS;
using the somewhat stricter entry criteria established for OHTS, we
estimate that we would have been able to recruit 101 eligible patients
during the same twelve month period. This proposal provides complete documentation of the ability of the
Department of Ophthalmology at the University of California, Davis to
screen large numbers of ocular hypertensive patients and to enroll at least
50 eligible patients over a 24-month period. Documentation is provided of the capabilities of the proposed investigators
and their staff for the performance of the study in accord with the details
of the OHTS Manual of Procedures, the nature and extent of their commitment
to the Ocular Hypertension Treatment Study at the University of California,
Davis, and a list of organizations and practitioners in the area who will
refer or follow patients screened for enrollment and randomization to
treatment in the OHTS clinical trial."
StatusFinished
Effective start/end date1/1/9412/31/09

Funding

  • National Institutes of Health: $178,785.00
  • National Institutes of Health
  • National Institutes of Health: $294,545.00
  • National Institutes of Health
  • National Institutes of Health: $233,081.00
  • National Institutes of Health
  • National Institutes of Health: $184,376.00
  • National Institutes of Health: $272,199.00
  • National Institutes of Health: $179,524.00
  • National Institutes of Health: $190,271.00
  • National Institutes of Health
  • National Institutes of Health: $228,707.00
  • National Institutes of Health: $140,100.00
  • National Institutes of Health
  • National Institutes of Health

Fingerprint

Ocular Hypertension
Ophthalmology
Therapeutics
Research Personnel
Documentation
Optic Neuritis
Visual Field Tests
Psychophysics
Health Maintenance Organizations
Private Practice
United States Department of Veterans Affairs
Random Allocation
Aptitude
Ambulatory Care Facilities
Glaucoma
Patient Selection
Reading
Visual Fields
Longitudinal Studies
Clinical Trials

ASJC

  • Medicine(all)