• 8892 Citations
  • 50 h-Index
1991 …2021
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Neoplasms Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Tumors Chemical Compounds
RNA Stability Medicine & Life Sciences
p53 Genes Medicine & Life Sciences
Cell Cycle Checkpoints Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1997 2021

The role of the p63-RBM38 loop in tumor suppression

Chen, X.

National Institutes of Health

4/1/163/31/21

Project: Research projectResearch Project

Premature Aging
Protein Isoforms
Neoplasms
RNA-Binding Proteins
Oncogene Proteins

CANCER CENTER SUPPORT GRANT-P30

DeGregorio, M., Matthews, D., Felton, J. S., deVere White, R. W., Radke, K., Lloyd, K. K., Gandara, D. R., Beckett, L. A., Gregg, J., Luciw, P. A., Kung, H., Gumerlock, P. H., Mack, P., Evans, C. P., Lara, P. N., Lam, K., Chen, X., Kelly, K., Cherry, S. R., Shacklett, B., Lloyd, K. C. K. & Chen, M. S.

National Institutes of Health

7/1/026/30/21

Project: Research projectCenter Core Grants

Neoplasms
Organized Financing
Research
Research Personnel
Clinical Trials
DNA Damage
Xeroderma Pigmentosum
Cell Survival
Rad30 protein
p53 Genes

Molecular Oncogenic Properties of Mutant p53

Chen, X.

National Institutes of Health

4/1/065/31/17

Project: Research projectResearch Project

Neoplasms
Mutation
p53 Genes
Arsenic
DNA Damage

Research Output 1991 2018

  • 8892 Citations
  • 50 h-Index
  • 154 Article
  • 1 Comment/debate
  • 1 Review article
1 Citations

Genetic ablation of Rbm38 promotes lymphomagenesis in the context of mutant p53 by downregulating PTEN

Zhang, J., Xu, E., Ren, C., Yang, H. J., Zhang, Y., Sun, W., Kong, X., Zhang, W., Chen, M., Huang, E. C. & Chen, X., Mar 15 2018, In : Cancer Research. 78, 6, p. 1511-1521 11 p.

Research output: Contribution to journalArticle

Down-Regulation
T-Lymphocytes
Neoplasms
RNA-Binding Proteins
AU Rich Elements
2 Citations

p53 tumor suppressor and iron homeostasis

Zhang, J. & Chen, X., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Tumors
Homeostasis
Iron
Neoplasms
Biochemical Phenomena

Rbm24, a target of p53, is necessary for proper expression of p53 and heart development

Zhang, M., Zhang, Y., Xu, E., Mohibi, S., de Anda, D. M., Jiang, Y., Zhang, J. & Chen, X., Jan 22 2018, (Accepted/In press) In : Cell Death and Differentiation. p. 1-13 13 p.

Research output: Contribution to journalArticle

Apoptosis
Endocardial Cushion Defects
Heart Failure
Peptide Initiation Factors
Messenger RNA

The Rbm38-p63 feedback loop is critical for tumor suppression and longevity

Jiang, Y., Xu, E., Zhang, J., Chen, M., Flores, E. & Chen, X., Mar 9 2018, (Accepted/In press) In : Oncogene. p. 1-10 10 p.

Research output: Contribution to journalArticle

Neoplasms
RNA-Binding Proteins
Cell Aging
RNA Stability
Fatty Liver
3 Citations

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

Zhang, Y., Qian, Y., Zhang, J., Yan, W., Jung, Y. S., Chen, M., Huang, E. C., Lloyd, K. C. K., Duan, Y., Wang, J., Liu, G. & Chen, X., Jun 15 2017, In : Genes and Development. 31, 12, p. 1243-1256 14 p.

Research output: Contribution to journalArticle

Iron Regulatory Protein 2
Ferredoxins
Oxidoreductases
Neoplasms
Iron