Xiaosong Jiang, MD; PhD

Associate Adjunct Professor

  • 1170 Citations
  • 18 h-Index
20062020

Research output per year

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Research Output

  • 1170 Citations
  • 18 h-Index
  • 22 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article
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Article

Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice

Jiang, X., Chen, X., Fukada, H., Serizawa, N., Devaraj, S. & Torok, N. J., Oct 2013, In : Hepatology. 58, 4, p. 1339-1348 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways

Jiang, X., Mikami, K., Venugopal, S., Li, Y. & Torok, N. J., Jul 2009, In : Journal of Hepatology. 51, 1, p. 139-148 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Digoxin improves steatohepatitis with differential involvement of liver cell subsets in mice through inhibition of PKM2 transactivation

Zhao, P., Han, S. N., Arumugam, S., Yousaf, M. N., Qin, Y., Jiang, J. X., Torok, N. J., Chen, Y., Mankash, M. S., Liu, J., Li, J., Iwakiri, Y. & Ouyang, X., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G387-G397

Research output: Contribution to journalArticle

1 Scopus citations

Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation

Jung, C. J., Iyengar, S., Blahnik, K. R., Ajuha, T. P., Jiang, X., Farnham, P. J. & Zern, M. A., Nov 28 2011, In : PLoS One. 6, 11, e27740.

Research output: Contribution to journalArticle

52 Scopus citations

Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo

Jiang, X., Chen, X., Hsu, D. K., Baghy, K., Serizawa, N., Scott, F., Takada, Y., Takada, Y., Fukada, H., Chen, J., Devaraj, S., Adamson, R., Liu, F-T. & Torok, N. J., Feb 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 4, p. 439-446 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation

Serizawa, N., Tian, J., Fukada, H., Baghy, K., Scott, F., Chen, X., Kiss, Z., Olson, K. A., Hsu, D., Liu, F-T., Torok, N. J., Zhao, B. & Jiang, X., Oct 1 2015, In : Laboratory Investigation. 95, 10, p. 1145-1156 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Galectin-3 regulates inflammasome activation in cholestatic liver injury

Tian, J., Yang, G., Chen, H. Y., Hsu, D. K., Tomilov, A., Olson, K. A., Dehnad, A., Fish, S. R., Cortopassi, G. A., Zhao, B., Liu, F-T., Gershwin, M. E., Torok, N. J. & Jiang, X., Dec 1 2016, In : FASEB Journal. 30, 12, p. 4202-4213 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Hepatocyte nicotinamide adenine dinucleotide phosphate reduced oxidase 4 regulates stress signaling, fibrosis, and insulin sensitivity during development of steatohepatitis in mice

Bettaieb, A., Jiang, X., Sasaki, Y., Chao, T. I., Kiss, Z., Chen, X., Tian, J., Katsuyama, M., Yabe-Nishimura, C., Xi, Y., Szyndralewiez, C., Schröder, K., Shah, A., Brandes, R. P., Haj, F. & Torok, N. J., Aug 1 2015, In : Gastroenterology. 149, 2, p. 468-480.e10

Research output: Contribution to journalArticle

63 Scopus citations

Human ESC self-renewal promoting microRNAs induce epithelial - Mesenchymal transition in hepatocytes by controlling the PTEN and TGFβ tumor suppressor signaling pathways

Jung, C. J., Iyengar, S., Blahnik, K. R., Jiang, X., Tahimic, C., Torok, N. J., deVere White, R. W., Farnham, P. J. & Zern, M. A., Jul 2012, In : Molecular Cancer Research. 10, 7, p. 979-991 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease

Medici, V., Ali, M. R., Seo, S., Aoki, C. A., Rossaro, L., Kim, K., Fuller, W. D., Vidovszky, T. J., Smith, W., Jiang, X., Maganti, K., Havel, P. J., Kamboj, A., Ramsamooj, R. & Torok, N. J., Dec 2010, In : Obesity. 18, 12, p. 2268-2273 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a rho guanosine triphosphatase-dependent mechanism

Jiang, X., Mikami, K., Shah, V. H. & Torok, N. J., Nov 2008, In : Hepatology. 48, 5, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

Jiang, X., Chen, X., Serizawa, N., Szyndralewiez, C., Page, P., Schröder, K., Brandes, R. P., Devaraj, S. & Torok, N. J., Jul 15 2012, In : Free Radical Biology and Medicine. 53, 2, p. 289-296 8 p.

Research output: Contribution to journalArticle

146 Scopus citations
165 Scopus citations

MLK3 as a regulator of disease progression in non-alcoholic steatohepatitis

Jiang, X. & Torok, N. J., 2014, In : Liver International. 34, 8, p. 1131-1132 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neutrophil–Hepatic Stellate Cell Interactions Promote Fibrosis in Experimental Steatohepatitis

Zhou, Z., Xu, M. J., Cai, Y., Wang, W., Jiang, X., Varga, Z. V., Feng, D., Pacher, P., Kunos, G., Torok, N. J. & Gao, B., Mar 1 2018, In : CMGH. 5, 3, p. 399-413 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Nonalcoholic steatohepatitis and the metabolic syndrome

Jiang, X. & Torok, N. J., Mar 1 2008, In : Metabolic Syndrome and Related Disorders. 6, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease

Sasaki, Y., Dehnad, A., Fish, S., Sato, A., Jiang, X., Tian, J., Schröder, K., Brandes, R. & Torok, N. J., Apr 6 2017, In : Scientific Reports. 7, 46144.

Research output: Contribution to journalArticle

6 Scopus citations

Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo

Zhan, S. S., Jiang, X., Wu, J., Halsted, C., Friedman, S. L., Zern, M. A. & Torok, N. J., Mar 2006, In : Hepatology. 43, 3, p. 435-443 9 p.

Research output: Contribution to journalArticle

173 Scopus citations

Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in Vivo

Jiang, X., Venugopal, S., Serizawa, N., Chen, X., Scott, F., Li, Y., Adamson, R., Devaraj, S., Shah, V., Gershwin, M. E., Friedman, S. L. & Torok, N. J., Oct 2010, In : Gastroenterology. 139, 4

Research output: Contribution to journalArticle

82 Scopus citations

The Aryl Hydrocarbon Receptor: A Key Bridging Molecule of External and Internal Chemical Signals

Tian, J., Feng, Y., Fu, H., Xie, H. Q., Jiang, X. & Zhao, B., Jun 16 2015, In : Environmental Science and Technology. 49, 16, p. 9518-9531 14 p.

Research output: Contribution to journalArticle

50 Scopus citations

The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease

Matsumoto, M., Zhang, J., Zhang, X., Liu, J., Jiang, X., Yamaguchi, K., Taruno, A., Katsuyama, M., Iwata, K., Ibi, M., Cui, W., Matsuno, K., Marunaka, Y., Itoh, Y., Torok, N. J. & Yabe-Nishimura, C., Feb 1 2018, In : Free Radical Biology and Medicine. 115, p. 412-420 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Wilson's disease: Changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease

Medici, V., Shibata, N. M., Kharbanda, K. K., LaSalle, J. M., Woods, R., Liu, S., Engelberg, J. A., Devaraj, S., Torok, N. J., Jiang, X., Havel, P. J., Lönnerdal, B., Kim, K. & Halsted, C. H., Feb 2013, In : Hepatology. 57, 2, p. 555-565 11 p.

Research output: Contribution to journalArticle

47 Scopus citations