• 5874 Citations
  • 42 h-Index
1980 …2019
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N-Acetylneuraminic Acid Chemical Compounds
Sialyltransferases Chemical Compounds
Polysaccharides Chemical Compounds
Oligosaccharides Chemical Compounds
Enzymes Chemical Compounds
Sialic Acids Medicine & Life Sciences
Neuraminidase Medicine & Life Sciences
Pasteurella multocida Medicine & Life Sciences

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Projects 1980 2017

Heparitin Sulfate
Heparin
Oligosaccharides
Carbohydrates
Uridine Diphosphate

Oligosaccharides as antimicrobials and prebiotics

Chen, X.

National Institutes of Health

7/15/105/31/15

Project: Research projectResearch Project

Prebiotics
Oligosaccharides
Human Milk
Carbohydrates
Bacteria

Chemical Glycobiology Symposium

Chen, X.

National Institutes of Health

9/11/068/31/07

Project: Research projectConference

Carbohydrates
Biochemistry
Pharmaceutical Preparations
Glycomics
Students

Research Output 1998 2019

Facile chemoenzymatic synthesis of Lewis a (Lea) antigen in gram-scale and sialyl Lewis a (sLea) antigens containing diverse sialic acid forms

Tasnima, N., Yu, H., Yan, X., Li, W., Xiao, A. & Chen, X., Jan 15 2019, In : Carbohydrate Research. 472, p. 115-121 7 p.

Research output: Contribution to journalArticle

N-Acetylneuraminic Acid
Sialyltransferases
Pasteurella multocida
N-acetylneuraminate lyase
Antigens

Strategies for chemoenzymatic synthesis of carbohydrates

Li, W., McArthur, J. B. & Chen, X., Jan 15 2019, In : Carbohydrate Research. 472, p. 86-97 12 p.

Research output: Contribution to journalArticle

Carbohydrates
Enzymes
Glycosylation
Glycosyltransferases
Glycoconjugates

Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry

Yuen, P. K., Green, S. A., Ashby, J., Lay, K. T., Santra, A., Chen, X., Horvath, M. P. & David, S. S., Jan 18 2019, In : ACS chemical biology. 14, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Click Chemistry
DNA Glycosylases
DNA Repair
Libraries
Repair
1 Citations

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen

Amon, R., Grant, O. C., Leviatan Ben-Arye, S., Makeneni, S., Nivedha, A. K., Marshanski, T., Norn, C., Yu, H., Glushka, J. N., Fleishman, S. J., Chen, X., Woods, R. J. & Padler-Karavani, V., Dec 1 2018, In : Scientific Reports. 8, 1, 10786.

Research output: Contribution to journalArticle

Tumor-Associated Carbohydrate Antigens
Polysaccharides
Antibodies
Screening
Monoclonal Antibodies
5 Citations

A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di-N-acetyllegionaminic Acid-Containing Glycosides

Santra, A., Xiao, A., Yu, H., Li, W., Li, Y., Ngo, L., McArthur, J. B. & Chen, X., Mar 5 2018, In : Angewandte Chemie - International Edition. 57, 11, p. 2929-2933 5 p.

Research output: Contribution to journalArticle

Glycosides
Mannose
N-acetylneuraminate lyase
Acids
Carbohydrates