• 5660 Citations
  • 41 h-Index
1980 …2018
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  • 2 Similar Profiles
N-Acetylneuraminic Acid Chemical Compounds
Sialyltransferases Chemical Compounds
Polysaccharides Medicine & Life Sciences
Oligosaccharides Chemical Compounds
Enzymes Chemical Compounds
Sialic Acids Medicine & Life Sciences
Neuraminidase Medicine & Life Sciences
Substrate Specificity Medicine & Life Sciences

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Projects 1980 2017

Heparitin Sulfate
Heparin
Oligosaccharides
Carbohydrates
Uridine Diphosphate

Oligosaccharides as antimicrobials and prebiotics

Chen, X.

National Institutes of Health

7/15/105/31/15

Project: Research projectResearch Project

Prebiotics
Oligosaccharides
Human Milk
Carbohydrates
Bacteria

Chemical Glycobiology Symposium

Chen, X.

National Institutes of Health

9/11/068/31/07

Project: Research projectConference

Carbohydrates
Biochemistry
Pharmaceutical Preparations
Glycomics
Students

Research Output 1998 2018

1 Citations

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen

Amon, R., Grant, O. C., Leviatan Ben-Arye, S., Makeneni, S., Nivedha, A. K., Marshanski, T., Norn, C., Yu, H., Glushka, J. N., Fleishman, S. J., Chen, X., Woods, R. J. & Padler-Karavani, V., Dec 1 2018, In : Scientific Reports. 8, 1, 10786.

Research output: Contribution to journalArticle

Tumor-Associated Carbohydrate Antigens
Polysaccharides
Antibodies
Screening
Monoclonal Antibodies
3 Citations

A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di-N-acetyllegionaminic Acid-Containing Glycosides

Santra, A., Xiao, A., Yu, H., Li, W., Li, Y., Ngo, L., McArthur, J. B. & Chen, X., Mar 5 2018, In : Angewandte Chemie - International Edition. 57, 11, p. 2929-2933 5 p.

Research output: Contribution to journalArticle

Glycosides
Mannose
N-acetylneuraminate lyase
Acids
Carbohydrates

Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera

Alisson-Silva, F., Liu, J. Z., Diaz, S. L., Deng, L., Gareau, M., Marchelletta, R., Chen, X., Nizet, V., Varki, N., Barrett, K. E. & Varki, A., Jun 1 2018, In : PLoS Pathogens. 14, 6, e1007133.

Research output: Contribution to journalArticle

Cholera
Vibrio cholerae
N-Acetylneuraminic Acid
Virulence Factors
Small Intestine
4 Citations

Interaction of Neisseria meningitidis Group X N-acetylglucosamine-1-phosphotransferase with its donor substrate

Ming, S. A., Cottman-Thomas, E., Black, N. C., Chen, Y., Veeramachineni, V., Peterson, D. C., Chen, X., Tedaldi, L. M., Wagner, G. K., Cai, C., Linhardt, R. J. & Vann, W. F., Feb 1 2018, In : Glycobiology. 28, 2, p. 100-107 8 p.

Research output: Contribution to journalArticle

Neisseria meningitidis
Uracil
Acetylglucosamine
Uridine Diphosphate
Hydroxyl Radical
1 Citations

Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk

Samraj, A. N., Bertrand, K. A., Luben, R., Khedri, Z., Yu, H., Nguyen, D., Gregg, C. J., Diaz, S. L., Sawyer, S., Chen, X., Eliassen, H., Padler-Karavani, V., Wu, K., Khaw, K. T., Willett, W. & Varki, A., Jun 1 2018, In : PloS one. 13, 6, e0197464.

Research output: Contribution to journalArticle

Bearings (structural)
red meat
sialic acids
Meats
N-Acetylneuraminic Acid