• 6580 Citations
  • 45 h-Index
1980 …2019
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Fingerprint Dive into the research topics where Xi Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
N-Acetylneuraminic Acid Chemical Compounds
Sialyltransferases Chemical Compounds
Polysaccharides Chemical Compounds
Oligosaccharides Chemical Compounds
Enzymes Chemical Compounds
Sialic Acids Medicine & Life Sciences
Neuraminidase Medicine & Life Sciences
Carbohydrates Chemical Compounds

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Projects 1980 2017

Heparitin Sulfate
Heparin
Oligosaccharides
Carbohydrates
Uridine Diphosphate
Prebiotics
Oligosaccharides
Human Milk
Carbohydrates
Bacteria

Research Output 1998 2019

9-Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases

Li, W., Santra, A., Yu, H., Slack, T. J., Muthana, M. M., Shi, D., Liu, Y. & Chen, X., Jun 7 2019, In : Journal of Organic Chemistry. 84, 11, p. 6697-6708 12 p.

Research output: Contribution to journalArticle

N-acetylneuraminate lyase
Neuraminidase
N-Acetylneuraminic Acid
Fluorine
Sialic Acids

A substrate tagging and two-step enzymatic reaction strategy for large-scale synthesis of 2,7-anhydro-sialic acid

Li, W., Ghosh, T., Bai, Y., Santra, A., Xiao, A. & Chen, X., Jun 1 2019, In : Carbohydrate Research. 479, p. 41-47 7 p.

Research output: Contribution to journalArticle

N-Acetylneuraminic Acid
Sialyltransferases
Purification
Substrates
Ruminococcus

Biochemical characterization of Helicobacter pylori α1–3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides

Bai, J., Wu, Z., Sugiarto, G., Gadi, M. R., Yu, H., Li, Y., Xiao, C., Ngo, A., Zhao, B., Chen, X. & Guan, W., Jul 1 2019, In : Carbohydrate Research. 480, p. 1-6 6 p.

Research output: Contribution to journalArticle

Fucosyltransferases
Human Milk
Oligosaccharides
Helicobacter pylori
Glycosyltransferases

Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy

Reuven, E. M., Leviatan Ben-Arye, S., Yu, H., Duchi, R., Perota, A., Conchon, S., Bachar Abramovitch, S., Soulillou, J. P., Galli, C., Chen, X. & Padler-Karavani, V., Mar 26 2019, In : ACS Nano. 13, 3, p. 2936-2947 12 p.

Research output: Contribution to journalArticle

vaccines
Cancer Vaccines
Vaccines
biomimetics
Biomimetics

Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography

Matthews, M. M., McArthur, J. B., Li, Y., Yu, H., Chen, X. & Fisher, A. J., Jan 1 2019, (Accepted/In press) In : Biochemistry.

Research output: Contribution to journalArticle

Cytidine Monophosphate
Cytidine
Crystallography
Neisseria meningitidis
N-Acetylneuraminic Acid