Philip Mack, PhD

Adjunct Professor

  • 4471 Citations
  • 38 h-Index
1995 …2021
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Projects 2002 2021

CANCER CENTER SUPPORT GRANT-P30

DeGregorio, M., Matthews, D., Felton, J. S., deVere White, R. W., Radke, K., Lloyd, K. K., Gandara, D. R., Beckett, L. A., Gregg, J., Luciw, P. A., Kung, H., Gumerlock, P. H., Mack, P., Evans, C. P., Lara, P. N., Lam, K., Chen, X., Kelly, K., Cherry, S. R., Shacklett, B., Lloyd, K. C. K. & Chen, M.

National Institutes of Health

7/1/026/30/21

Project: Research project

Neoplasms
Organized Financing
Research
Research Personnel
Clinical Trials
Tumor Biomarkers
Lung Neoplasms
Proteins
Osteopontin
Plasminogen Activator Inhibitor 1

Research Output 1995 2019

Novel Synergistic Combination of Mitotic Arrest and Promotion of Apoptosis for Treatment of Pancreatic Adenocarcinoma

Duan, Z., Chinn, D., Tu, M. J., Zhang, Q. Y., Huynh, J., Chen, J., Mack, P., Yu, A. & Kim, E., Apr 1 2019, In : Translational Oncology. 12, 4, p. 683-692 10 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Aurora Kinase A
Adenocarcinoma
Apoptosis
Organoids
1 Citation (Scopus)
Open Access
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Neoplasms
Mutation
13 Citations (Scopus)

Antitumor activity of osimertinib, an irreversible mutant-selective EGFR tyrosine kinase inhibitor, in NSCLC harboring EGFR exon 20 insertions

Floc'h, N., Martin, M. J., Riess, J., Orme, J. P., Staniszewska, A. D., Menard, L., Cuomo, M. E., O'Neill, D. J., Ward, R. A., Finlay, R. M. V., McKerrecher, D., Cheng, M., Vang, D. P., Burich, R. A., Keck, J. G., Gandara, D. R., Mack, P. & Cross, D. A. E., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 885-896 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Exons
Heterografts
Insertional Mutagenesis
2 Citations (Scopus)

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, A. B., O'Donnell, R. T., Semrad, T., Mack, P., Blanchard, S., Bahary, N., Jiang, Y., Yen, Y., Wright, J., Chen, H., Lenz, H. J. & Gandara, D. R., Mar 8 2018, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Toxicity
Hepatocellular Carcinoma
Somatomedins
Liver Neoplasms
Peritonitis

Bone turnover biomarkers identify unique prognostic risk groups in men with castration resistant prostate cancer and skeletal metastases: Results from SWOG S0421

Lara, P. N., Plets, M., Tangen, C., Gertz, E., Vogelzang, N. J., Hussain, M., Twardowski, P. W., Garzotto, M. G., Monk, J. P., Carducci, M., Goldkorn, A., Mack, P., Thompson, I., Van Loan, M. & Quinn, D. I., Jan 1 2018, In : Cancer Treatment and Research Communications. 16, p. 18-23 6 p.

Research output: Contribution to journalArticle

bis(2,3,3,3-tetrachloropropyl) ether
Bone Remodeling
Castration
Prostatic Neoplasms
Biomarkers