• 4941 Citations
  • 38 h-Index
19952020

Research output per year

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Research Output

  • 4941 Citations
  • 38 h-Index
  • 77 Article
  • 3 Chapter
  • 2 Comment/debate
  • 2 Review article
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Article
2007

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Ota, S., Zhou, Z. Q., Keene, D. R., Knoepfler, P. S. & Hurlin, P. J., Apr 2007, In : Development. 134, 8, p. 1583-1592 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Myc goes global: New tricks for an old oncogene

Knoepfler, P. S., Jun 1 2007, In : Cancer Research. 67, 11, p. 5061-5063 3 p.

Research output: Contribution to journalArticle

97 Scopus citations

Myc stimulates B lymphocyte differentiation and amplifies calcium signaling

Habib, T., Park, H., Tsang, M., De Alborán, I. M., Nicks, A., Wilson, L., Knoepfler, P. S., Andrews, S., Rawlings, D. J., Eisenman, R. N. & Iritani, B. M., Nov 19 2007, In : Journal of Cell Biology. 179, 4, p. 717-731 15 p.

Research output: Contribution to journalArticle

66 Scopus citations
2006

Myc influences global chromatin structure

Knoepfler, P. S., Zhang, X. Y., Cheng, P. F., Gafken, P. R., McMahon, S. B. & Eisenman, R. N., Jun 21 2006, In : EMBO Journal. 25, 12, p. 2723-2734 12 p.

Research output: Contribution to journalArticle

295 Scopus citations

Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes

Knoepfler, P. S. & Kenney, A. M., Jan 1 2006, In : Cell Cycle. 5, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

74 Scopus citations

N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development

Zindy, F., Knoepfler, P. S., Xie, S., Sherr, C. J., Eisenman, R. N. & Roussel, M. F., Aug 1 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 31, p. 11579-11583 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

N-myc is an essential downstream effector of shh signaling during both normal and neoplastic cerebellar growth

Hatton, B. A., Knoepfler, P. S., Kenney, A. M., Rowitch, D. H., Moreno De Alborán, I., Olson, J. M. & Eisenman, R. N., Sep 1 2006, In : Cancer Research. 66, 17, p. 8655-8661 7 p.

Research output: Contribution to journalArticle

116 Scopus citations
2005

Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors

Orian, A., Grewal, S. S., Knoepfler, P. S., Edgar, B. A., Parkhurst, S. M. & Eisenman, R. N., 2005, In : Cold Spring Harbor Symposia on Quantitative Biology. 70, p. 299-307 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Okubo, T., Knoepfler, P. S., Eisenman, R. N. & Hogan, B. L. M., Mar 2005, In : Development. 132, 6, p. 1363-1374 12 p.

Research output: Contribution to journalArticle

174 Scopus citations
2004

HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations

Swanson, K. A., Knoepfler, P. S., Huang, K., Kang, R. S., Cowley, S. M., Laherty, C. D., Eisenman, R. N. & Radhakrishnan, I., Aug 2004, In : Nature Structural and Molecular Biology. 11, 8, p. 738-746 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential

Berkes, C. A., Bergstrom, D. A., Penn, B., Seaver, K. J., Knoepfler, P. S. & Tapscott, S. J., May 21 2004, In : Molecular Cell. 14, 4, p. 465-477 13 p.

Research output: Contribution to journalArticle

247 Scopus citations
2002

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

Knoepfler, P. S., Cheng, P. F. & Eisenman, R. N., Oct 15 2002, In : Genes and Development. 16, 20, p. 2699-2712 14 p.

Research output: Contribution to journalArticle

361 Scopus citations
2001

HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

Knoepfler, P. S., Sykes, D. B., Pasillas, M. & Kamps, M. P., Sep 6 2001, In : Oncogene. 20, 39, p. 5440-5448 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
76 Scopus citations

The Smad transcriptional corepressor TGIF recruits mSin3

Wotton, D., Knoepfler, P. S., Laherty, C. D., Eisenman, R. N. & Massagué, J., 2001, In : Cell Growth and Differentiation. 12, 9, p. 457-463 7 p.

Research output: Contribution to journalArticle

106 Scopus citations
2000

Direct interaction of two homeoproteins, Homothorax and Extradenticle, is essential for EXD nuclear localization and function

Jaw, T. J., You, L. R., Knoepfler, P. S., Yao, L. C., Pai, C. Y., Tang, C. Y., Chang, L. P., Berthelsen, J., Blasi, F., Kamps, M. P. & Sun, Y. H., Mar 1 2000, In : Mechanisms of Development. 91, 1-2, p. 279-291 13 p.

Research output: Contribution to journalArticle

74 Scopus citations
1999

A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with Pbx-Meis1/Prep1

Knoepfler, P. S., Bergstrom, D. A., Uetsuki, T., Dac-Korytko, L., Sun, Y. H., Wright, W. E., Tapscott, S. J. & Kamps, M. P., Sep 15 1999, In : Nucleic Acids Research. 27, 18, p. 3752-3761 10 p.

Research output: Contribution to journalArticle

88 Scopus citations

An inhibitory switch derepressed by Pbx, Hox, and Meis/Prep1 partners regulates DNA-binding by Pbx1 and E2a-Pbx1 and is dispensable for myeloid immortalization by E2a-Pbx1

Calvo, K. R., Knoepfler, P. S., McGrath, S. & Kamps, M. P., Dec 23 1999, In : Oncogene. 18, 56, p. 8033-8043 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Sin meets NuRD and other tails of repression

Knoepfler, P. S. & Eisenman, R. N., Nov 24 1999, In : Cell. 99, 5, p. 447-450 4 p.

Research output: Contribution to journalArticle

289 Scopus citations
1997

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

Knoepfler, P. S., Calvo, K. R., Chen, H., Antonarakis, S. E. & Kamps, M. P., Dec 23 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 26, p. 14553-14558 6 p.

Research output: Contribution to journalArticle

159 Scopus citations
34 Scopus citations
1996
60 Scopus citations
1995

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes

Lu, Q., Knoepfler, P. S., Scheele, J., Wright, D. D. & Kamps, M. P., 1995, In : Molecular and Cellular Biology. 15, 7, p. 3786-3795 10 p.

Research output: Contribution to journalArticle

131 Scopus citations
26 Scopus citations
140 Scopus citations

Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion

Knoepfler, P. S., Bloor, C. M. & Carroll, S. M., Jun 1995, In : Journal of Molecular and Cellular Cardiology. 27, 6, p. 1317-1324 8 p.

Research output: Contribution to journalArticle

21 Scopus citations