• 4917 Citations
  • 37 h-Index
19952020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 4917 Citations
  • 37 h-Index
  • 77 Article
  • 3 Chapter
  • 2 Comment/debate
  • 2 Review article
2020

Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling

Chen, K. Y., Bush, K., Klein, R. H., Cervantes, V., Lewis, N., Naqvi, A., Carcaboso, A. M., Lechpammer, M. & Knoepfler, P. S., Dec 1 2020, In : Communications Biology. 3, 1, 363.

Research output: Contribution to journalArticle

Open Access
2019

Rapid change of a cohort of 570 unproven stem cell clinics in the USA over 3 years

Knoepfler, P. S., Jan 1 2019, In : Regenerative Medicine. 14, 8, p. 735-740 6 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells

Somanath, P., Bush, K. M. & Knoepfler, P. S., Jan 1 2018, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

4 Scopus citations

Gene editing: sloppy definitions mislead

Knoepfler, P., Dec 1 2018, In : Nature. 564, 7736, 1 p.

Research output: Contribution to journalComment/debate

Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer

Klein, R. H., Tung, P. Y., Somanath, P., Fehling, H. J. & Knoepfler, P. S., Aug 1 2018, In : Stem Cell Research. 31, p. 83-94 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mapping and driving the stem cell ecosystem

Knoepfler, P. S., Oct 1 2018, In : Regenerative Medicine. 13, 7

Research output: Contribution to journalReview article

5 Scopus citations

Reviewing post-publication peer review

Knoepfler, P. S., Jul 23 2018, Getting to Good: Research Integrity in the Biomedical Sciences. Springer International Publishing, p. 380-384 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The FDA and the US direct-to-consumer marketplace for stem cell interventions: A temporal analysis

Knoepfler, P. S. & Turner, L. G., Jan 1 2018, In : Regenerative Medicine. 13, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Too Much Carrot and Not Enough Stick in New Stem Cell Oversight Trends

Knoepfler, P. S., Jan 1 2018, (Accepted/In press) In : Cell Stem Cell.

Research output: Contribution to journalArticle

7 Scopus citations
2017

Behavior of xeno-Transplanted undifferentiated human induced pluripotent stem cells is impacted by microenvironment without evidence of tumors

Martínez-Cerdeño, V., Barrilleaux, B. L., McDonough, A., Ariza, J., Yuen, B. T. K., Somanath, P., Le, C. T., Steward, C., Horton-Sparks, K. & Knoepfler, P. S., Oct 1 2017, In : Stem Cells and Development. 26, 19, p. 1409-1423 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells

Somanath, P., Herndon Klein, R. & Knoepfler, P. S., Oct 1 2017, In : PLoS One. 12, 10, e0185627.

Research output: Contribution to journalArticle

5 Scopus citations

The stem cell hard sell: Report from a clinic’s patient recruitment seminar

Knoepfler, P. S., Jan 1 2017, In : Stem cells translational medicine. 6, 1, p. 14-16 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Selling Stem Cells in the USA: Assessing the Direct-to-Consumer Industry

Turner, L. & Knoepfler, P. S., 2016, (Accepted/In press) In : Cell Stem Cell.

Research output: Contribution to journalArticle

182 Scopus citations

To CRISPR and beyond: The evolution of genome editing in stem cells

Chen, K. Y. & Knoepfler, P. S., Dec 1 2016, In : Regenerative Medicine. 11, 8, p. 801-816 16 p.

Research output: Contribution to journalReview article

6 Scopus citations

When patients reach out, scientists should reach back carefully

Knoepfler, P. S., Mar 3 2016, In : Nature Medicine. 22, 3, p. 230 1 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2015

Epigenetic mechanisms of tumorigenicity manifesting in stem cells

Tung, P. Y. & Knoepfler, P. S., Apr 30 2015, In : Oncogene. 34, 18, p. 2288-2296 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

From bench to FDA to bedside: US regulatory trends for new stem cell therapies

Knoepfler, P. S., Mar 1 2015, In : Advanced Drug Delivery Reviews. 82, p. 192-196 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Reviewing post-publication peer review

Knoepfler, P. S., May 1 2015, In : Trends in Genetics. 31, 5, p. 221-223 3 p.

Research output: Contribution to journalArticle

37 Scopus citations
2014

Histone H3.3 regulates dynamic chromatin states during spermatogenesis

Yuen, B. T. K., Bush, K. M., Barrilleaux, B. L., Cotterman, R. & Knoepfler, P. S., 2014, In : Development (Cambridge). 141, 18, p. 3483-3494 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Miz-1 activates gene expression via a novel consensus DNA binding motif

Barrilleaux, B. L., Burow, D., Lockwood, S. H., Yu, A., Segal, D. & Knoepfler, P. S., Jul 1 2014, In : PLoS One. 9, 7, e101151.

Research output: Contribution to journalArticle

14 Scopus citations
2013
10 Scopus citations

Chromatin immunoprecipitation assays for Myc and N-Myc

Barrilleaux, B. L., Cotterman, R. & Knoepfler, P. S., 2013, Methods in Molecular Biology. Vol. 1012. p. 117-133 17 p. (Methods in Molecular Biology; vol. 1012).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chromatin immunoprecipitation assays for Myc and N-Myc

Barrilleaux, B. L., Cotterman, R. & Knoepfler, P. S., 2013, Methods in Molecular Biology. Humana Press Inc., Vol. 1012. p. 117-133 17 p. (Methods in Molecular Biology; vol. 1012).

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

Bush, K. M., Yuen, B. T. K., Barrilleaux, B. L., Riggs, J. W., O'Geen, H., Cotterman, R. F. & Knoepfler, P. S., 2013, In : Epigenetics and Chromatin. 6, 1, 7.

Research output: Contribution to journalArticle

50 Scopus citations

Histone H3.3 Mutations: A Variant Path to Cancer

Yuen, B. T. K. & Knoepfler, P. S., Nov 11 2013, In : Cancer Cell. 24, 5, p. 567-574 8 p.

Research output: Contribution to journalArticle

73 Scopus citations

Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes

Tung, P. Y., Varlakhanova, N. V. & Knoepfler, P. S., 2013, In : Stem Cells. 31, 11, p. 2330-2342 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Induced pluripotency and oncogenic transformation are related processes

Riggs, J. W., Barrilleaux, B. L., Varlakhanova, N., Bush, K. M., Chan, V. & Knoepfler, P. S., Jan 1 2013, In : Stem Cells and Development. 22, 1, p. 37-50 14 p.

Research output: Contribution to journalArticle

63 Scopus citations

Key action items for the stem cell field: Looking ahead to 2014

Knoepfler, P. S., Dec 1 2013, In : Stem Cells and Development. 22, SUPPL.1, p. 10-12 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain

Laskowski, A. I. & Knoepfler, P. S., Jun 14 2013, In : Biochemical and Biophysical Research Communications. 435, 4, p. 551-556 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Scientists: You really need to get out of the lab more

Knoepfler, P. S., Sep 2013, In : Nature Medicine. 19, 9, p. 1086 1 p.

Research output: Contribution to journalArticle

2012

Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc

Pshenichnaya, I., Schouwey, K., Armaro, M., Larue, L., Knoepfler, P. S., Eisenman, R. N., Trumpp, A., Delmas, V. & Beermann, F., May 2012, In : Pigment Cell and Melanoma Research. 25, 3, p. 312-325 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Induced Pluripotent Stem Cells Show Metabolomic Differences to Embryonic Stem Cells in Polyunsaturated Phosphatidylcholines and Primary Metabolism

Meissen, J. K., Yuen, B. T. K., Kind, T., Riggs, J. W., Barupal, D. K., Knoepfler, P. S. & Fiehn, O., Oct 15 2012, In : PLoS One. 7, 10, e46770.

Research output: Contribution to journalArticle

47 Scopus citations

Key anticipated regulatory issues for clinical use of human induced pluripotent stem cells

Knoepfler, P. S., Sep 2012, In : Regenerative Medicine. 7, 5, p. 713-720 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells

Martinez-Cerdeno, V., Lemen, J. M., Chan, V., Wey, A., Lin, W., Dent, S. R. & Knoepfler, P. S., Jun 26 2012, In : PLoS One. 7, 6, e39456.

Research output: Contribution to journalArticle

30 Scopus citations

Utf1: Goldilocks for ESC bivalency

Laskowski, A. I. & Knoepfler, P. S., Dec 7 2012, In : Cell Stem Cell. 11, 6, p. 732-734 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Inducing iPSCs to Escape the dish

Barrilleaux, B. & Knoepfler, P. S., Aug 5 2011, In : Cell Stem Cell. 9, 2, p. 103-111 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells

Varlakhanova, N., Cotterman, R., Bradnam, K., Korf, I. F. & Knoepfler, P. S., 2011, In : Epigenetics and Chromatin. 4, 1, 20.

Research output: Contribution to journalArticle

21 Scopus citations

My year as a stem-cell blogger

Knoepfler, P. S., Jul 28 2011, In : Nature. 475, 7357, p. 425 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

N-myc controls proliferation, morphogenesis, and patterning of the inner ear

Frutos, E. D., Hernández, I. L., Vendrell, V., Neves, J., Gallozzi, M., Gutsche, K., Quintana, L., Sharpe, J., Knoepfler, P. S., Eisenman, R. N., Trumpp, A., Giráldez, F. & Schimmang, T., May 11 2011, In : Journal of Neuroscience. 31, 19, p. 7178-7189 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Transduction of human cells with polymer-complexed ecotropic lentivirus for enhanced biosafety

Barrilleaux, B. & Knoepfler, P. S., Jul 2011, In : Journal of Visualized Experiments. 53, e2822.

Research output: Contribution to journalArticle

5 Scopus citations
2010

Arrestin' the hedgehog: Shh limits its own signaling via β-Arrestin1

Knoepfler, P. S., Nov 1 2010, In : Cell Cycle. 9, 21, p. 4260-4261 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
28 Scopus citations

C-myc and N-myc in the developing brain

Wey, A. & Knoepfler, P. S., May 2010, In : Aging. 2, 5, p. 261-262 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.

Wey, A. & Knoepfler, P. S., Jun 2010, In : Oncotarget. 1, 2, p. 120-130 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Myc maintains embryonic stem cell pluripotency and self-renewal

Varlakhanova, N. V., Cotterman, R. F., deVries, W. N., Morgan, J., Donahue, L. R., Murray, S., Knowles, B. B. & Knoepfler, P. S., Jul 2010, In : Differentiation. 80, 1, p. 9-19 11 p.

Research output: Contribution to journalArticle

120 Scopus citations

The death of MyMouseHouse: Lessons for systems for the efficient management of mouse colonies

Knoepfler, P. S. & Bush, K. M., Jan 2010, In : DMM Disease Models and Mechanisms. 3, 1-2, p. 9-10 2 p.

Research output: Contribution to journalArticle

Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex

Kuwahara, A., Hirabayashi, Y., Knoepfler, P. S., Taketo, M. M., Sakai, J., Kodama, T. & Gotoh, Y., Apr 1 2010, In : Development. 137, 7, p. 1035-1044 10 p.

Research output: Contribution to journalArticle

58 Scopus citations
2009

Acting locally and globally: Myc's ever-expanding roles on chromatin

Varlakhanova, N. V. & Knoepfler, P. S., Oct 1 2009, In : Cancer Research. 69, 19, p. 7487-7490 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Deconstructing stem cell tumorigenicity: A roadmap to safe regenerative medicine

Knoepfler, P. S., May 2009, In : Stem Cells. 27, 5, p. 1050-1056 7 p.

Research output: Contribution to journalArticle

310 Scopus citations

Division and apoptosis of E2f-deficient retinal progenitors

Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G. & Bremner, R., Dec 17 2009, In : Nature. 462, 7275, p. 925-929 5 p.

Research output: Contribution to journalArticle

106 Scopus citations