• 2276 Citations
  • 29 h-Index
1981 …2020

Research output per year

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Research Output

  • 2276 Citations
  • 29 h-Index
  • 83 Article
  • 1 Chapter
2020
Open Access
2019

Completion of the Vimentin Rod Domain Structure Using Experimental Restraints: A New Tool for Exploring Intermediate Filament Assembly and Mutations

Gae, D. D., Budamagunta, M. S., Hess, J. F., McCarrick, R. M., Lorigan, G. A., FitzGerald, P. G. & Voss, J. C., Oct 1 2019, In : Structure. 27, 10, p. 1547-1560.e4

Research output: Contribution to journalArticle

1 Scopus citations

Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1 +/- ) in mice

Kim, S., Thomasy, S. M., Raghunathan, V. K., Teixeira, L. B. C., Moshiri, A., FitzGerald, P. G. & Murphy, C. J., Jan 1 2019, In : Molecular vision. 25, p. 129-142 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins

Gerhart, J., Behling, K., Paessler, M., Milton, L. B., Bramblett, G., Garcia, D., Pitts, M., Hurtt, R., Crawford, M., Lackman, R., Nguyen, D., Infanti, J., FitzGerald, P. G. & George-Weinsteinid, M., Apr 1 2019, In : PloS one. 14, 4, e0214758.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Deletion of GLUT1 in mouse lens epithelium leads to cataract formation

Swarup, A., Bell, B. A., Du, J., Han, J. Y. S., Soto, J., Abel, E. D., Bravo-Nuevo, A., FitzGerald, P. G., Peachey, N. S. & Philp, N. J., Jul 1 2018, In : Experimental Eye Research. 172, p. 45-53 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Myo/Nog cells are present in the ciliary processes, on the zonule of Zinn and posterior capsule of the lens following cataract surgery

Gerhart, J., Withers, C., Gerhart, C., Werner, L., Mamalis, N., Bravo-Nuevo, A., Scheinfeld, V., FitzGerald, P. G., Getts, R. & George-Weinstein, M., Jun 1 2018, In : Experimental Eye Research. 171, p. 101-105 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Production of recombinant human tektin 1, 2, and 4 and in vitro assembly of human tektin 1

Budamagunta, M. S., Guo, F., Sun, N., Shibata, B., FitzGerald, P. G., Voss, J. C. & Hess, J. F., Jan 1 2018, In : Cytoskeleton. 75, 1, p. 3-11 9 p.

Research output: Contribution to journalArticle

2016

Expression of the type vi intermediate filament proteins CP49 and filensin in the mouse lens epithelium

FitzGerald, P. G., Sun, N., Shibata, B. & Hess, J. F., 2016, In : Molecular Vision. 22, p. 970-989 20 p.

Research output: Contribution to journalArticle

3 Scopus citations

Probing the Local Secondary Structure of Human Vimentin with Electron Spin Echo Envelope Modulation (ESEEM) Spectroscopy

Liu, L., Hess, J., Sahu, I. D., FitzGerald, P. G., McCarrick, R. M. & Lorigan, G. A., Dec 8 2016, In : Journal of Physical Chemistry B. 120, 48, p. 12321-12326 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tropomodulin 1 regulation of actin is required for the formation of large paddle protrusions between mature lens fiber cells

Cheng, C., Nowak, R. B., Biswas, S. K., Lo, W. K., FitzGerald, P. G. & Fowler, V. M., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4084-4099 16 p., 16.

Research output: Contribution to journalArticle

8 Scopus citations
2015

An alternative means of retaining ocular structure and improving immunoreactivity for light microscopy studies

Sun, N., Shibata, B., Hess, J. F. & FitzGerald, P. G., Apr 16 2015, In : Molecular Vision. 21, p. 428-442 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Characterization of an early-onset, autosomal recessive, progressive retinal degeneration in bengal cats

Ofri, R., Reilly, C. M., Maggs, D. J., FitzGerald, P. G., Shilo-Benjamini, Y., Koehler, K. G., Grahn, R. A., Splawski, D. D. & Lyons, L. A., 2015, In : Investigative Ophthalmology and Visual Science. 56, 9, p. 5299-5308 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Role of Aquaporin 0 in lens biomechanics

Sindhu Kumari, S., Gupta, N., Shiels, A., FitzGerald, P. G., Menon, A. G., Mathias, R. T. & Varadaraj, K., Apr 19 2015, In : Biochemical and Biophysical Research Communications. 462, 4, p. 339-345 7 p., 33884.

Research output: Contribution to journalArticle

22 Scopus citations
2014

Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development

Manthey, A. L., Lachke, S. A., FitzGerald, P. G., Mason, R. W., Scheiblin, D. A., McDonald, J. H. & Duncan, M. K., Feb 2014, In : Mechanisms of Development. 131, 1, p. 86-110 25 p.

Research output: Contribution to journalArticle

31 Scopus citations

Myo/Nog cells: targets for preventing the accumulation of skeletal muscle-like cells in the human lens

Gerhart, J., Greenbaum, M., Scheinfeld, V., FitzGerald, P. G., Crawford, M., Bravo-Nuevo, A., Pitts, M. & George-Weinstein, M., 2014, In : PLoS One. 9, 4, p. e95262

Research output: Contribution to journalArticle

8 Scopus citations

Myo/Nog Cells: Targets for Preventing the Accumulation of Skeletal Muscle-Like Cells in the Human Lens

Gerhart, J., Greenbaum, M., Scheinfeld, V., FitzGerald, P. G., Crawford, M., Bravo-Nuevo, A., Pitts, M. & George-Weinstein, M., Apr 15 2014, In : PLoS One. 9, 4, e95262.

Research output: Contribution to journalArticle

7 Scopus citations

Rapid light-induced activation of retinal microglia in mice lacking Arrestin-1

Levine, E. S., Zam, A., Zhang, P., Pechko, A., Wang, X., FitzGerald, P. G., Pugh Jr, E. N., Zawadzki, R. & Burns, M. E., 2014, In : Vision Research. 102, p. 71-79 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2013

Carbon turnover in the water-soluble protein of the adult human lens

Stewart, D. N., Lango, J., Nambiar, K. P., Falso, M. J. S., FitzGerald, P. G., Rocke, D. M., Hammock, B. D. & Buchholz, B. A., Feb 25 2013, In : Molecular Vision. 19, p. 463-475 13 p.

Research output: Contribution to journalArticle

22 Scopus citations
17 Scopus citations
2012

A role for γs-crystallin in the organization of actin and fiber cell maturation in the mouse lens

Fan, J., Dong, L., Mishra, S., Chen, Y., FitzGerald, P. G. & Wistow, G., Aug 2012, In : FEBS Journal. 279, 16, p. 2892-2904 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34 + cells in NOD-SCID mice with acute ischemia-reperfusion injury

Park, S. S., Caballero, S., Bauer, G., Shibata, B., Roth, A., Fitzgerald, P. G., Forward, K. I., Zhou, P., McGee, J., Telander, D. G., Grant, M. B. & Nolta, J. A., Feb 2012, In : Investigative Ophthalmology and Visual Science. 53, 2, p. 986-994 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Natural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets

Weikel, K. A., FitzGerald, P. G., Shang, F., Andrea Caceres, M., Bian, Q., Handa, J. T., Stitt, A. W. & Taylor, A., Feb 2012, In : Investigative Ophthalmology and Visual Science. 53, 2, p. 622-632 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography

Aziz, A., Hess, J. F., Budamagunta, M. S., Voss, J. C., Kuzin, A. P., Huang, Y. J., Xiao, R., Montelione, G. T., FitzGerald, P. G. & Hunt, J. F., Aug 17 2012, In : Journal of Biological Chemistry. 287, 34, p. 28349-28361 13 p.

Research output: Contribution to journalArticle

32 Scopus citations
2011

Further analysis of the lens phenotype in Lim2-deficient mice

Shi, Y., De Maria, A. B., Wang, H., Mathias, R. T., FitzGerald, P. G. & Bassnett, S., Sep 2011, In : Investigative Ophthalmology and Visual Science. 52, 10, p. 7332-7339 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Intermediate filaments regulate tissue size and stiffness in the murine lens

Fudge, D. S., McCuaig, J. V., van Stralen, S., Hess, J. F., Wang, H., Mathias, R. T. & FitzGerald, P. G., May 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3860-3867 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane

Castorino, J. J., Gallagher-Colombo, S. M., Levin, A. V., FitzGerald, P. G., Polishook, J., Kloeckener-Gruissem, B., Ostertag, E. & Philp, N. J., Aug 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 6774-6784 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2010

Site-directed spin labeling and electron paramagnetic resonance determination of vimentin head domain structure

Aziz, A., Hess, J. F., Budamagunta, M. S., Voss, J. C. & FitzGerald, P. G., May 14 2010, In : Journal of Biological Chemistry. 285, 20, p. 15278-15285 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2009

Distribution and structure of efferent synapses in the chicken retina

Lindstrom, S. H., Nacsa, N., Blankenship, T., FitzGerald, P. G., Weller, C., Vaney, D. I. & Wilson, M., Mar 2009, In : Visual Neuroscience. 26, 2, p. 215-226 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
16 Scopus citations

Lens intermediate filaments

FitzGerald, P. G., Feb 2 2009, In : Experimental Eye Research. 88, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Periplakin interactions with lens intermediate and beaded filaments

Yoon, K. H. & FitzGerald, P. G., Mar 2009, In : Investigative Ophthalmology and Visual Science. 50, 3, p. 1283-1289 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance

Pittenger, J. T., Hess, J. F., Budamagunta, M. S., Voss, J. C. & FitzGerald, P. G., Oct 14 2008, In : Biochemistry. 47, 41, p. 10863-10870 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Resisting the effects of aging: A function for the fiber cell beaded filament

Yoon, K. H., Blankenship, T., Shibata, B. & FitzGerald, P. G., Mar 2008, In : Investigative Ophthalmology and Visual Science. 49, 3, p. 1030-1036 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2007

Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains

Budamagunta, M. S., Hess, J. F., FitzGerald, P. G. & Voss, J. C., May 2007, In : Cell Biochemistry and Biophysics. 48, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identifying the role of specific motifs in the lens fiber cell-specific intermediate filament phakosin

Pittenger, J. T., Hess, J. F. & FitzGerald, P. G., Nov 2007, In : Investigative Ophthalmology and Visual Science. 48, 11, p. 5132-5141 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mapping the structural transition in an amyloidogenic apolipoprotein A-I

Lagerstedt, J. O., Cavigiolio, G., Roberts, L. M., Hong, H. S., Jin, L-W., FitzGerald, P. G., Oda, M. N. & Voss, J. C., Aug 28 2007, In : Biochemistry. 46, 34, p. 9693-9699 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Structural specializations emerging late in mouse lens fiber cell differentiation

Blankenship, T., Bradshaw, L., Shibata, B. & FitzGerald, P. G., Jul 2007, In : Investigative Ophthalmology and Visual Science. 48, 7, p. 3269-3276 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Treatment of keratin intermediate filaments with sulfur mustard analogs

Hess, J. F. & FitzGerald, P. G., Aug 3 2007, In : Biochemical and Biophysical Research Communications. 359, 3, p. 616-621 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
2006

Characterization of the linker 2 region in human vimentin using site-directed spin labeling and electron paramagnetic resonance

Hess, J. F., Budamagunta, M. S., Shipman, R. L., FitzGerald, P. G. & Voss, J. C., Oct 3 2006, In : Biochemistry. 45, 39, p. 11737-11743 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

In Vitro Techniques

Harris, J. R., Almouzni, G., Kirschner, D., Dimitrova, D., Nickerson, J. A., Underwood, J., Wagner, S., Korbei, B., Foisner, R., Walther, T. C., Hetzer, M., Peters, R., Walev, I., de Kroon, A. I. P. M., Staffhorst, R. W. H. M., de Kruijff, B., Burger, K. N. J., Netto, L. E. S., Bertrand, E., Alimonti, J. B. & 49 others, Greenberg, A. H., Xiao, J., Pradhan, A., Liu, Y., Paiement, J., Young, R., Goñi, F. M., Villar, A. V., Contreras, F. X., Alonso, A., Peter, B. J., Mills, I. G., Higgins, M. K., Brown, W. J., Chambers, K., Doody, A., Cheng, C. Y., Mruk, D. D., Yang, C., Kirchhoff, H., Haase, W., Boggasch, S., Paulsen, H., Benesova, J., Liffers, S. T., Rögner, M., Gao, Y. S., Sztul, E., Thiemann, M., Fahimi, H. D., Gniadecki, R., Gajkowska, B., Bane, S. L., Hess, J. F., Voss, J. C., FitzGerald, P. G., Hisanaga, S. I., Sasaki, T., Uéda, K., Town, T., Tan, J., Milton, N. G. N., Chi, R., Keller, T. C. S., Kriajevska, M., Bronstein, I., Lukanidin, E., Holmes, D. F. & Kadler, K. E., Jul 3 2006, Cell Biology Protocols. wiley, p. 201-378 178 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2005
13 Scopus citations
2004

Characterization of a mutation in the lens-specific CP49 in the 129 strain of mouse

Alizadeh, A., Clark, J., Seeberger, T., Hess, J., Blankenship, T. & FitzGerald, P. G., Mar 2004, In : Investigative Ophthalmology and Visual Science. 45, 3, p. 884-891 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Digital image capture and quantification of subtle lens opacities in rodents

Seeberger, T. M., Matsumoto, Y., Alizadeh, A., FitzGerald, P. G. & Clark, J. I., Jan 2004, In : Journal of Biomedical Optics. 9, 1, p. 116-120 5 p.

Research output: Contribution to journalArticle

12 Scopus citations
38 Scopus citations
2003

Analysis of non-crystallin lens fiber cell gene expression in c-Maf -/- mice

DePianto, D. J., Blankenship, T. N., Hess, J. F. & FitzGerald, P. G., 2003, In : Molecular Vision. 9, p. 288-294 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Isolation and characterization of the human CP49 gene promoter

DePianto, D. J., Hess, J. F., Blankenship, T. N. & FitzGerald, P. G., Jan 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 1, p. 235-243 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Targeted Deletion of the Lens Fiber Cell-Specific Intermediate Filament Protein Filensin

Alizadeh, A., Clark, J., Seeberger, T., Hess, J., Blankenship, T. & FitzGerald, P. G., Dec 2003, In : Investigative Ophthalmology and Visual Science. 44, 12, p. 5252-5258 7 p.

Research output: Contribution to journalArticle

57 Scopus citations
2002

Evolution of the tapetum

Schwab, I. R., Yuen, C. K., Buyukmihci, N. C., Blankenship, T. N., FitzGerald, P. G., Eagle, R. C., Sadun, A. A. & Ernest, T. J., 2002, In : Transactions of the American Ophthalmological Society. 100, p. 187-200 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Real-time observation of coiled-coil domains and subunit assembly in intermediate filaments

Hess, J. F., Voss, J. C. & FitzGerald, P. G., Sep 20 2002, In : Journal of Biological Chemistry. 277, 38, p. 35516-35522 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Targeted genomic deletion of the lens-specific intermediate filament protein CP49

Alizadeh, A., Clark, J. I., Seeberger, T., Hess, J., Blankenship, T., Spicer, A. & FitzGerald, P. G., Dec 1 2002, In : Investigative Ophthalmology and Visual Science. 43, 12, p. 3722-3727 6 p.

Research output: Contribution to journalArticle

62 Scopus citations