Nigel J Maclachlan, PhD; MS

Professor Emeritus

  • 7504 Citations
  • 50 h-Index
1976 …2020

Research output per year

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Research Output

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A 29K envelope glycoprotein of equine arteritis virus expresses neutralization determinants recognized by murine monoclonal antibodies

Balasuriya, U. B. R., Rossitto, P. V., DeMaula, C. D. & Maclachlan, N. J., 1993, In : Journal of General Virology. 74, 11, p. 2525-2529 5 p.

Research output: Contribution to journalArticle

54 Scopus citations
47 Scopus citations

Acute encephalitis, polyarthritis, and myocarditis associated with West Nile virus infection in a dog

Cannon, A. B., Luff, J. A., Brault, A., Maclachlan, N. J., Case, J. B., Green, E. N. G. & Sykes, J. E., Sep 2006, In : Journal of Veterinary Internal Medicine. 20, 5, p. 1219-1223 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

A deterministic model to quantify risk and guide mitigation strategies to reduce bluetongue virus transmission in California dairy cattle

Mayo, C., Shelley, C., Maclachlan, N. J., Gardner, I., Hartley, D. & Barker, C., Nov 1 2016, In : PLoS One. 11, 11, e0165806.

Research output: Contribution to journalArticle

5 Scopus citations

African horse sickness caused by genome reassortment and reversion to virulence of live, attenuated vaccine viruses, South Africa, 2004–2014

Weyer, C. T., Grewar, J. D., Burger, P., Rossouw, E., Lourens, C., Joone, C., Le Grange, M., Coetzee, P., Venter, E., Martin, D. P., Maclachlan, N. J. & Guthrie, A. J., Dec 1 2016, In : Emerging Infectious Diseases. 22, 12, p. 2087-2096 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

African horse sickness in naturally infected, immunised horses

Weyer, C. T., Quan, M., Joone, C., Lourens, C. W., Maclachlan, N. J. & Guthrie, A. J., Jan 2013, In : Equine Veterinary Journal. 45, 1, p. 117-119 3 p.

Research output: Contribution to journalArticle

22 Scopus citations

Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses

Balasuriya, U. B. R., Heidner, H. W., Davis, N. L., Wagner, H. M., Hullinger, P., Hedges, J. F., Williams, J. C., Johnston, R. E., Wilson, W. D., Liu, I. & Maclachlan, N. J., Feb 22 2002, In : Vaccine. 20, 11-12, p. 1609-1617 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

Amino acid substitutions in the structural or nonstructural proteins of a vaccine strain of equine arteritis virus are associated with its attenuation

Zhang, J., Go, Y. Y., Maclachlan, N. J., Meade, B. J., Timoney, P. J. & Balasuriya, U. B. R., Sep 1 2008, In : Virology. 378, 2, p. 355-362 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
9 Scopus citations

An epizootic of endometritis in gilts.

Maclachlan, N. J. & Dial, G. D., Jan 1987, In : Veterinary Pathology. 24, 1, p. 92-94 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Anthropogenic and meteorological factors influence vector abundance and prevalence of bluetongue virus infection of dairy cattle in California

Mayo, C. E., Gardner, I., Mullens, B. A., Barker, C., Gerry, A. C., Guthrie, A. J. & Maclachlan, N. J., Mar 23 2012, In : Veterinary Microbiology. 155, 2-4, p. 158-164 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Antiviral responses of bluetongue virus-inoculated bovine fetuses and their dams.

MacLachlan, N. J., Schore, C. E. & Osburn, B. I., Jul 1984, In : American Journal of Veterinary Research. 45, 7, p. 1469-1473 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Aplasia of the epididymis and vas deferens in the dog

Copland, M. D. & Maclachlan, N. J., 1976, In : Journal of Small Animal Practice. 17, 7, p. 443-449 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

A review of potential bluetongue virus vaccine strategies

Mayo, C., Lee, J., Kopanke, J. & Maclachlan, N. J., Oct 11 2016, (Accepted/In press) In : Veterinary Microbiology.

Research output: Contribution to journalArticle

10 Scopus citations

A simplified procedure for oligonucleotide fingerprint analysis of multiple bluetongue virus genome segments utilizing small gels

Heidner, H. W., Iezzi, L. G. & Maclachlan, N. J., 1989, In : Journal of Virological Methods. 26, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A survey of feline viral upper respiratory tract infections.

Maclachlan, N. J. & Burgess, G. W., Oct 1978, In : New Zealand Veterinary Journal. 26, 10, p. 260-261 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Blauzungenkrankheit bei Schweizer schafrassen: Klinische Symptome nach experimenteller infektion mit dem BTV-Serotyp 8

Translated title of the contribution: Clinical signs observed in Swiss sheep after experimental bluetongue virus serotype 8 infectionWorwa, G., Thür, B., Griot, C., Hofmann, M., Maclachlan, N. J. & Chaignat, V., Oct 2008, In : Schweizer Archiv fur Tierheilkunde. 150, 10, p. 491-498 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Bluetongue: History, global epidemiology, and pathogenesis

Maclachlan, N. J., Nov 1 2011, In : Preventive Veterinary Medicine. 102, 2, p. 107-111 5 p.

Research output: Contribution to journalArticle

109 Scopus citations

Bluetongue

Maclachlan, N. J., Mayo, C. E., Daniels, P. W., Savini, G., Zientara, S. & Gibbs, E. P. J., Aug 1 2015, In : OIE Revue Scientifique et Technique. 34, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Bluetongue and equine viral arteritis viruses as models of virus-induced fetal injury and abortion

Maclachlan, N. J., Conley, A. J. & Kennedy, P. C., Jul 2 2000, In : Animal Reproduction Science. 60-61, p. 643-651 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

Bluetongue disease and the molecular epidemiology of viruses from the western United States

Osburn, B., De Mattos, C. A., De Mattos, C. C. & Maclachlan, N. J., Jun 1996, In : Comparative Immunology, Microbiology and Infectious Diseases. 19, 3, p. 181-190 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bluetongue disease in dogs associated with contaminated vaccine [1]

Akita, G. Y., Ianconescu, M., Maclachlan, N. J., Osburn, B. & Greene, R. T., 1994, In : Veterinary Record. 134, 11, p. 283-284 2 p.

Research output: Contribution to journalArticle

46 Scopus citations

Bluetongue vaccination in Europe

Zientara, S., Maclachlan, N. J., Calistri, P., Sanchez-Vizcaino, J. M. & Savini, G., Sep 2010, In : Expert Review of Vaccines. 9, 9, p. 989-991 3 p.

Research output: Contribution to journalArticle

56 Scopus citations

Bluetongue virus: Virology, pathogenesis and immunity

Schwartz-Cornil, I., Mertens, P. P. C., Contreras, V., Hemati, B., Pascale, F., Bréard, E., Mellor, P. S., Maclachlan, N. J. & Zientara, S., Sep 2008, In : Veterinary Research. 39, 5, 46.

Research output: Contribution to journalArticle

207 Scopus citations

Bluetongue virus genome remains stable throughout prolonged infection of cattle.

Heidner, H. W., Maclachlan, N. J., Fuller, F. J., Richards, R. G. & Whetter, L. E., Oct 1988, In : Journal of General Virology. 69

Research output: Contribution to journalArticle

20 Scopus citations

Bluetongue virus-induced activation of primary bovine lung microvascular endothelial cells

DeMaula, C. D., Leutenegger, C. M., Jutila, M. A. & Maclachlan, N. J., 2002, In : Veterinary Immunology and Immunopathology. 86, 3-4, p. 147-157 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bluetongue virus-induced encephalopathy in fetal cattle.

MacLachlan, N. J., Osburn, B. I., Ghalib, H. W. & Stott, J. L., Jul 1985, In : Veterinary Pathology. 22, 4, p. 415-417 3 p.

Research output: Contribution to journalArticle

37 Scopus citations

Bluetongue virus-induced hydranencephaly in cattle.

Maclachlan, N. J. & Osburn, B., Sep 1983, In : Veterinary Pathology. 20, 5, p. 563-573 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Bluetongue virus-induced interferon in cattle.

Maclachlan, N. J. & Thompson, J., Jun 1985, In : American Journal of Veterinary Research. 46, 6, p. 1238-1241 4 p.

Research output: Contribution to journalArticle

41 Scopus citations
23 Scopus citations

Bluetongue virus infection alters the impedance of monolayers of bovine endothelial cells as a result of cell death

Drew, C. P., Gardner, I., Mayo, C. E., Matsuo, E., Roy, P. & Maclachlan, N. J., Jul 2010, In : Veterinary Immunology and Immunopathology. 136, 1-2, p. 108-115 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Bluetongue virus infection creates light averse Culicoides vectors and serious errors in transmission risk estimates

McDermott, E. G., Mayo, C. E., Gerry, A. C., Laudier, D., Maclachlan, N. J. & Mullens, B. A., Sep 17 2015, In : Parasites and Vectors. 8, 1, 460.

Research output: Contribution to journalArticle

14 Scopus citations

Bluetongue virus infection of bovine monocytes

Whetter, L. E., Maclachlan, N. J., Gebhard, D. H., Heidner, H. W. & Moore, P. F., 1989, In : Journal of General Virology. 70, 7, p. 1663-1676 14 p.

Research output: Contribution to journalArticle

52 Scopus citations

Canine pericardial mesothelioma.

McDonough, S. P., Maclachlan, N. J. & Tobias, A. H., May 1992, In : Veterinary Pathology. 29, 3, p. 256-260 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Changes in the outer capsid proteins of bluetongue virus serotype ten that abrogate neutralization by monoclonal antibodies

Demaula, C. D., Bonneau, K. R. & Maclachlan, N. J., Mar 2000, In : Virus Research. 67, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Characterization of equine E-selectin

Hedges, J. F., Demaula, C. D., Moore, B. D., Mclaughlin, B. E., Simon, S. I. & Maclachlan, N. J., 2001, In : Immunology. 103, 4, p. 498-504 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Characterization of the neutralization determinants of equine arteritis virus using recombinant chimeric viruses and site-specific mutagenesis of an infectious cDNA clone

Balasuriya, U. B. R., Dobbe, J. C., Heidner, H. W., Smalley, V. L., Navarrette, A., Snijder, E. J. & Maclachlan, N. J., Apr 10 2004, In : Virology. 321, 2, p. 235-246 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Colostral transmission of bluetongue virus nucleic acid among newborn dairy calves in California

Mayo, C. E., Crossley, B., Hietala, S. K., Gardner, I., Breitmeyer, R. E. & Maclachlan, N. J., Aug 2010, In : Transboundary and Emerging Diseases. 57, 4, p. 277-281 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Communicable diseases and equine viral diseases

MacLachlan, J., Sep 2005, In : Journal of Equine Veterinary Science. 25, 9, p. 402-403 2 p.

Research output: Contribution to journalArticle

Comparison of tissue reactions produced by Haemophilus pleuropneumoniae vaccines made with six different adjuvants in swine

Straw, B. E., Maclachlan, N. J., Corbett, W. T., Carter, P. B. & Schey, H. M., 1985, In : Canadian Journal of Comparative Medicine. 49, 2, p. 149-151 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

Comparison of two trapping methods for Culicoides biting midges and determination of African horse sickness virus prevalence in midge populations at Onderstepoort, South Africa

Scheffer, E. G., Venter, G. J., Labuschagne, K., Page, P. C., Mullens, B. A., Maclachlan, N. J., Osterrieder, N. & Guthrie, A. J., Apr 30 2012, In : Veterinary Parasitology. 185, 2-4, p. 265-273 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Comparison of virologic and serologic responses of lambs and calves infected with bluetongue virus Serotype 10

Richards, R. G., Maclachlan, N. J., Heidner, H. W. & Fuller, F. J., 1988, In : Veterinary Microbiology. 18, 3-4, p. 233-242 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Complete genome sequences of four African horse sickness virus strains from a commercial tetravalent live attenuated vaccine

Guthrie, A. J., Coetzee, P., Martin, D. P., Lourens, C. W., Venter, E. H., Weyer, C. T., Joone, C., Grange, M. L., Harper, C. K., Howell, P. G. & Maclachlan, N. J., 2015, In : Genome Announcements. 3, 6, e0137515.

Research output: Contribution to journalArticle

2 Scopus citations

Complete genome sequences of the three African horse sickness virus strains from a commercial trivalent live attenuated vaccine

Guthrie, A. J., Coetzee, P., Martin, D. P., Lourens, C. W., Venter, E. H., Weyer, C. T., Joone, C., Grange, M. L., Harper, C. K., Howell, P. G. & Maclachlan, N. J., 2015, In : Genome Announcements. 3, 4, e00814-15.

Research output: Contribution to journalArticle

6 Scopus citations

Complete genome sequences of virus strains isolated from bottle A of the South African live attenuated bluetongue virus vaccine

Coetzee, P., Guthrie, A. J., Ebersohn, K., Maclachlan, J. N., Ismail, A., van Schalkwyk, A. & Venter, E. H., May 28 2020, In : Microbiology Resource Announcements. 9, 22, e00310-20.

Research output: Contribution to journalArticle

Open Access

Congenital bluetongue virus infection.

Maclachlan, N. J. & Osburn, B., 1988, In : Progress in Clinical and Biological Research. 281, p. 33-47 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Congenital encephalopathy in a calf.

Brown, C. C. & Maclachlan, N. J., Nov 1983, In : Veterinary Pathology. 20, 6, p. 770-773 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Detection of antibodies to equine arteritis virus by enzyme linked immunosorbant assays utilizing G(L), M and N proteins expressed from recombinant baculoviruses

Hedges, J. F., Balasuriya, U. B. R., Ahmad, S., Timoney, P. J., McCollum, W. H., Yilma, T. & Maclachlan, N. J., Dec 1 1998, In : Journal of Virological Methods. 76, 1-2, p. 127-137 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Detection of antibodies to West Nile virus in equine sera using microsphere immunoassay

Balasuriya, U. B. R., Shi, P. Y., Wong, S. J., Demarest, V. L., Gardner, I., Hullinger, P., Ferraro, G. L., Boone, J. D., De Cino, C. L., Glaser, A. L., Renshaw, R. W., Ledizet, M., Koski, R. A. & Maclachlan, N. J., Jul 2006, In : Journal of Veterinary Diagnostic Investigation. 18, 4, p. 392-395 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Detection of bluetongue virus in the blood of inoculated calves: comparison of virus isolation, PCR assay, and in vitro feeding of Culicoides variipennis

Maclachlan, N. J., Nunamaker, R. A., Katz, J. B., Sawyer, M. M., Akita, G. Y., Osburn, B. & Tabachnick, W. J., Mar 1994, In : Archives of Virology. 136, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

116 Scopus citations