Nigel J Maclachlan, PhD; MS

Professor Emeritus

  • 7475 Citations
  • 50 h-Index
1976 …2020

Research output per year

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Research Output

2020

Experimental infection of mid-gestation pregnant female and intact Male sheep with Zika virus

Schwarz, E. R., Oliveira, L. J., Bonfante, F., Pu, R., Pozor, M. A., Maclachlan, N. J., Beachboard, S., Barr, K. L. & Long, M. T., Jan 1 2020, In : Viruses. 12, 3, 291.

Research output: Contribution to journalArticle

Open Access
2019

Bluetongue and epizootic hemorrhagic disease viruses: recent developments with these globally re-emerging arboviral infections of ruminants

Maclachlan, N. J., Zientara, S., Wilson, W. C., Richt, J. A. & Savini, G., Feb 1 2019, In : Current Opinion in Virology. 34, p. 56-62 7 p.

Research output: Contribution to journalReview article

9 Scopus citations

Experimental Infection of Pregnant Female Sheep with Zika Virus During Early Gestation

Schwarz, E. R., Pozor, M. A., Pu, R., Barr, K. L., Beachboard, S. E., Maclachlan, N. J., Prakoso, D. & Long, M. T., Aug 29 2019, In : Viruses. 11, 9

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2017

Dynamics of African horse sickness virus nucleic acid and antibody in horses following immunization with a commercial polyvalent live attenuated vaccine

Weyer, C. T., Grewar, J. D., Burger, P., Joone, C., Lourens, C., Maclachlan, N. J. & Guthrie, A. J., Apr 25 2017, In : Vaccine. 35, 18, p. 2504-2510 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
7 Scopus citations
2016

A deterministic model to quantify risk and guide mitigation strategies to reduce bluetongue virus transmission in California dairy cattle

Mayo, C., Shelley, C., Maclachlan, N. J., Gardner, I., Hartley, D. & Barker, C., Nov 1 2016, In : PLoS One. 11, 11, e0165806.

Research output: Contribution to journalArticle

5 Scopus citations

African horse sickness caused by genome reassortment and reversion to virulence of live, attenuated vaccine viruses, South Africa, 2004–2014

Weyer, C. T., Grewar, J. D., Burger, P., Rossouw, E., Lourens, C., Joone, C., Le Grange, M., Coetzee, P., Venter, E., Martin, D. P., Maclachlan, N. J. & Guthrie, A. J., Dec 1 2016, In : Emerging Infectious Diseases. 22, 12, p. 2087-2096 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

A review of potential bluetongue virus vaccine strategies

Mayo, C., Lee, J., Kopanke, J. & Maclachlan, N. J., Oct 11 2016, (Accepted/In press) In : Veterinary Microbiology.

Research output: Contribution to journalArticle

10 Scopus citations

Detection of equine arteritis virus by two chromogenic RNA in situ hybridization assays (conventional and RNAscope®) and assessment of their performance in tissues from aborted equine fetuses

Carossino, M., Loynachan, A. T., Maclachlan, N. J., Drew, C., Shuck, K. M., Timoney, P. J., Del Piero, F. & Balasuriya, U. B. R., Nov 1 2016, In : Archives of Virology. 161, 11, p. 3125-3136 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fenner's veterinary virology: Fifth edition

Maclachlan, N. J., Dubovi, E. J., Barthold, S. W., Swayne, D. E. & Winton, J. R., Nov 21 2016, Elsevier Inc. 581 p.

Research output: Book/ReportBook

OIEBTLABNET: La rete basata sul web dei Laboratori di Referenza dell’OIE per la Bluetongue

Translated title of the contribution: OIEBTLABNET: The web-based network of the OIE bluetongue reference laboratoriesConte, A., Daniels, P., Goffredo, M., Ostlund, E. N., Di Lorenzo, A., Savini, L., Tora, S., Lubisi, B. A., Calistri, P., Cerella, A., Bruno, R., Di Sabatino, D., Ippoliti, C., Monaco, F., Mertens, P. P. C., Lorusso, A., Capobianco, A., Ripani, A., Maclachlan, N. J. & Savini, G., Jul 1 2016, In : Veterinaria italiana. 52, 3-4, p. 187-193 7 p.

Research output: Contribution to journalArticle

Svernamento del virus della Bluetongue in zone temperate

Translated title of the contribution: Overwintering of bluetongue virus in temperate zonesMayo, C. E., Mullens, B. A., Gibbs, E. P. J. & Maclachlan, N. J., Jul 1 2016, In : Veterinaria italiana. 52, 3-4, p. 243-246 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Bluetongue

Maclachlan, N. J., Mayo, C. E., Daniels, P. W., Savini, G., Zientara, S. & Gibbs, E. P. J., Aug 1 2015, In : OIE Revue Scientifique et Technique. 34, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Bluetongue virus infection creates light averse Culicoides vectors and serious errors in transmission risk estimates

McDermott, E. G., Mayo, C. E., Gerry, A. C., Laudier, D., Maclachlan, N. J. & Mullens, B. A., Sep 17 2015, In : Parasites and Vectors. 8, 1, 460.

Research output: Contribution to journalArticle

14 Scopus citations

Complete genome sequences of four African horse sickness virus strains from a commercial tetravalent live attenuated vaccine

Guthrie, A. J., Coetzee, P., Martin, D. P., Lourens, C. W., Venter, E. H., Weyer, C. T., Joone, C., Grange, M. L., Harper, C. K., Howell, P. G. & Maclachlan, N. J., 2015, In : Genome Announcements. 3, 6, e0137515.

Research output: Contribution to journalArticle

2 Scopus citations

Complete genome sequences of the three African horse sickness virus strains from a commercial trivalent live attenuated vaccine

Guthrie, A. J., Coetzee, P., Martin, D. P., Lourens, C. W., Venter, E. H., Weyer, C. T., Joone, C., Grange, M. L., Harper, C. K., Howell, P. G. & Maclachlan, N. J., 2015, In : Genome Announcements. 3, 4, e00814-15.

Research output: Contribution to journalArticle

6 Scopus citations

Development of three triplex real-time reverse transcription PCR assays for the qualitative molecular typing of the nine serotypes of African horse sickness virus

Weyer, C. T., Joone, C., Lourens, C. W., Monyai, M. S., Koekemoer, O., Grewar, J. D., van Schalkwyk, A., Majiwa, P. O. A., Maclachlan, N. J. & Guthrie, A. J., Oct 1 2015, In : Journal of Virological Methods. 223, p. 69-74 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Epizootic haemorrhagic disease

Maclachlan, N. J., Zientara, S., Savini, G. & Daniels, P. W., Aug 1 2015, In : OIE Revue Scientifique et Technique. 34, 2, p. 341-351 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Evoluzione della Bluetongue: Storia dalle origini

Translated title of the contribution: The changing global face of bluetongue: From the beginningMaclachlan, N. J., Oct 1 2015, In : Veterinaria italiana. 51, 4, p. 249-251 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Lack of evidence for laboratory and natural vertical transmission of bluetongue virus in culicoides sonorensis (Diptera: Ceratopogonidae)

Osborne, C. J., Mayo, C. E., Mullens, B. A., McDermott, E. G., Gerry, A. C., Reisen, W. & Maclachlan, N. J., Mar 1 2015, In : Journal of Medical Entomology. 52, 2, p. 274-277 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Orbiviruses: A North American Perspective

McVey, D. S., Drolet, B. S., Ruder, M. G., Wilson, W. C., Nayduch, D., Pfannenstiel, R., Cohnstaedt, L. W., Maclachlan, N. J. & Gay, C. G., Jun 1 2015, In : Vector-Borne and Zoonotic Diseases. 15, 6, p. 335-338 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
18 Scopus citations
2014

Estimating Culicoides sonorensis biting midge abundance using digital image analysis

Osborne, C. J., Mayo, C. E., Mullens, B. A. & Maclachlan, N. J., Dec 1 2014, In : Medical and Veterinary Entomology. 28, 4, p. 461-464 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Experiences with infectious cDNA clones of equine arteritis virus: Lessons learned and insights gained

Balasuriya, U. B. R., Zhang, J., Go, Y. Y. & Maclachlan, N. J., 2014, In : Virology. 462-463, 1, p. 388-403 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
22 Scopus citations
19 Scopus citations

Serological response of foals to polyvalent and monovalent live-attenuated African horse sickness virus vaccines

Crafford, J. E., Lourens, C. W., Smit, T. K., Gardner, I., Maclachlan, N. J. & Guthrie, A. J., Jun 17 2014, In : Vaccine. 32, 29, p. 3611-3616 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

The immune response of ruminant livestock to bluetongue virus: From type I interferon to antibody

Maclachlan, N. J., Henderson, C., Schwartz-Cornil, I. & Zientara, S., Mar 28 2014, In : Virus Research. 182, p. 71-77 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Whole genome sequencing and phylogenetic analysis of Bluetongue virus serotype 2 strains isolated in the Americas including a novel strain from the western United States

Gaudreault, N. N., Mayo, C. E., Jasperson, D. C., Crossley, B., Breitmeyer, R. E., Johnson, D. J., Ostlund, E. N., Maclachlan, N. J. & Wilson, W. C., 2014, In : Journal of Veterinary Diagnostic Investigation. 26, 4, p. 553-557 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

African horse sickness in naturally infected, immunised horses

Weyer, C. T., Quan, M., Joone, C., Lourens, C. W., Maclachlan, N. J. & Guthrie, A. J., Jan 2013, In : Equine Veterinary Journal. 45, 1, p. 117-119 3 p.

Research output: Contribution to journalArticle

22 Scopus citations

Diagnostic accuracy of a duplex real-time reverse transcription quantitative PCR assay for detection of African horse sickness virus

Guthrie, A. J., Maclachlan, N. J., Joone, C., Lourens, C. W., Weyer, C. T., Quan, M., Monyai, M. S. & Gardner, I., Apr 2013, In : Journal of Virological Methods. 189, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Equine arteritis virus

Balasuriya, U. B. R., Go, Y. Y. & Maclachlan, N. J., Nov 29 2013, In : Veterinary Microbiology. 167, 1-2, p. 93-122 30 p.

Research output: Contribution to journalArticle

47 Scopus citations

Equine Viral Arteritis

Balasuriya, U. B. R. & MacLachlan, N. J., Oct 2013, Equine Infectious Diseases: Second Edition. Elsevier Inc.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Novel serotype of bluetongue virus, Western North America

Maclachlan, N. J., Wilson, W. C., Crossley, B., Mayo, C. E., Jasperson, D. C., Breitmeyer, R. E. & Whiteford, A. M., Apr 2013, In : Emerging Infectious Diseases. 19, 4, p. 665-666 2 p.

Research output: Contribution to journalArticle

23 Scopus citations

Passive transfer and rate of decay of maternal antibody against African horse sickness virus in South African Thoroughbred foals

Crafford, J. E., Lourens, C. W., Gardner, I., Maclachlan, N. J. & Guthrie, A. J., Sep 2013, In : Equine Veterinary Journal. 45, 5, p. 604-607 4 p.

Research output: Contribution to journalArticle

10 Scopus citations
71 Scopus citations
2012

Anthropogenic and meteorological factors influence vector abundance and prevalence of bluetongue virus infection of dairy cattle in California

Mayo, C. E., Gardner, I., Mullens, B. A., Barker, C., Gerry, A. C., Guthrie, A. J. & Maclachlan, N. J., Mar 23 2012, In : Veterinary Microbiology. 155, 2-4, p. 158-164 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Comparison of two trapping methods for Culicoides biting midges and determination of African horse sickness virus prevalence in midge populations at Onderstepoort, South Africa

Scheffer, E. G., Venter, G. J., Labuschagne, K., Page, P. C., Mullens, B. A., Maclachlan, N. J., Osterrieder, N. & Guthrie, A. J., Apr 30 2012, In : Veterinary Parasitology. 185, 2-4, p. 265-273 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

The combination of abundance and infection rates of Culicoides sonorensis estimates risk of subsequent bluetongue virus infection of sentinel cattle on California dairy farms

Mayo, C. E., Mullens, B. A., Gerry, A. C., Barker, C., Mertens, P. P. C., Maan, S., Maan, N., Gardner, I., Guthrie, A. J. & Maclachlan, N. J., Jun 8 2012, In : Veterinary Parasitology. 187, 1-2, p. 295-301 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Bluetongue: History, global epidemiology, and pathogenesis

Maclachlan, N. J., Nov 1 2011, In : Preventive Veterinary Medicine. 102, 2, p. 107-111 5 p.

Research output: Contribution to journalArticle

108 Scopus citations

Equid gammaherpesviruses: Persistent bystanders or true pathogens?

Brault, S. A. & Maclachlan, N. J., Jan 2011, In : Veterinary Journal. 187, 1, p. 14-15 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic heterogeneity and variation in viral load during equid herpesvirus-2 infection of foals

Brault, S. A., Bird, B. H., Balasuriya, U. B. R. & Maclachlan, N. J., Jan 27 2011, In : Veterinary Microbiology. 147, 3-4, p. 253-261 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2010

Bluetongue vaccination in Europe

Zientara, S., Maclachlan, N. J., Calistri, P., Sanchez-Vizcaino, J. M. & Savini, G., Sep 2010, In : Expert Review of Vaccines. 9, 9, p. 989-991 3 p.

Research output: Contribution to journalArticle

56 Scopus citations
22 Scopus citations

Bluetongue virus infection alters the impedance of monolayers of bovine endothelial cells as a result of cell death

Drew, C. P., Gardner, I., Mayo, C. E., Matsuo, E., Roy, P. & Maclachlan, N. J., Jul 2010, In : Veterinary Immunology and Immunopathology. 136, 1-2, p. 108-115 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Colostral transmission of bluetongue virus nucleic acid among newborn dairy calves in California

Mayo, C. E., Crossley, B., Hietala, S. K., Gardner, I., Breitmeyer, R. E. & Maclachlan, N. J., Aug 2010, In : Transboundary and Emerging Diseases. 57, 4, p. 277-281 5 p.

Research output: Contribution to journalArticle

29 Scopus citations
26 Scopus citations

Fatal bluetongue virus infection in an alpaca (Vicugna pacos) in California

Ortega, J., Crossley, B., Dechant, J. E., Drew, C. P. & Maclachlan, N. J., Jan 1 2010, In : Journal of Veterinary Diagnostic Investigation. 22, 1, p. 134-136 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Fenner's Veterinary Virology: Fourth Edition

Maclachlan, N. J. & Dubovi, E. J., Nov 2010, Elsevier Inc. 507 p.

Research output: Book/ReportBook

2 Scopus citations
53 Scopus citations