Niels C Pedersen, BS; DVM; PhD

Professor Emeritus

  • 14804 Citations
  • 68 h-Index
1968 …2020

Research output per year

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Research Output

2020

Antiviral treatment using the adenosine nucleoside analogue GS-441524 in cats with clinically diagnosed neurological feline infectious peritonitis

Dickinson, P. J., Bannasch, M., Thomasy, S. M., Murthy, V. D., Vernau, K. M., Liepnieks, M., Montgomery, E., Knickelbein, K. E., Murphy, B. & Pedersen, N. C., Jan 1 2020, (Accepted/In press) In : Journal of Veterinary Internal Medicine.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy

99 Lives Consortium, Jan 1 2020, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Author Correction: Applications and efficiencies of the first cat 63K DNA array (Scientific Reports, (2018), 8, 1, (7024), 10.1038/s41598-018-25438-0)

Gandolfi, B., Alhaddad, H., Abdi, M., Bach, L. H., Creighton, E. K., Davis, B. W., Decker, J. E., Dodman, N. H., Ginns, E. I., Grahn, J. C., Grahn, R. A., Haase, B., Haggstrom, J., Hamilton, M. J., Helps, C. R., Kurushima, J. D., Lohi, H., Longeri, M., Malik, R., Meurs, K. M. & 12 others, Montague, M. J., Mullikin, J. C., Murphy, W. J., Nilson, S. M., Pedersen, N. C., Peterson, C. B., Rusbridge, C., Saif, R., Shelton, G. D., Warren, W. C., Wasim, M. & Lyons, L. A., Dec 1 2019, In : Scientific Reports. 9, 1, 4664.

Research output: Contribution to journalComment/debate

Open Access

Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor

Perera, K. D., Rathnayake, A., Liu, H., Pedersen, N. C., Groutas, W. C., Chang, K. O. & Kim, Y., Oct 1 2019, In : Veterinary Microbiology. 237, 108398.

Research output: Contribution to journalArticle

3 Scopus citations

Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV)

Mustaffa-Kamal, F., Liu, H., Pedersen, N. C. & Sparger, E. E., May 22 2019, In : BMC veterinary research. 15, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis

Pedersen, N. C., Perron, M., Bannasch, M., Montgomery, E., Murakami, E., Liepnieks, M. & Liu, H., Jan 1 2019, In : Journal of Feline Medicine and Surgery.

Research output: Contribution to journalArticle

23 Scopus citations

Fifty years’ fascination with FIP culminates in a promising new antiviral

Pedersen, N. C., Apr 1 2019, In : Journal of Feline Medicine and Surgery. 21, 4, p. 269-270 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations
2018

Applications and efficiencies of the first cat 63K DNA array

Gandolfi, B., Alhaddad, H., Abdi, M., Bach, L. H., Creighton, E. K., Davis, B. W., Decker, J. E., Dodman, N. H., Grahn, J. C., Grahn, R. A., Haase, B., Haggstrom, J., Hamilton, M. J., Helps, C. R., Kurushima, J. D., Lohi, H., Longeri, M., Malik, R., Meurs, K. M., Montague, M. J. & 11 others, Mullikin, J. C., Murphy, W. J., Nilson, S. M., Pedersen, N. C., Peterson, C. B., Rusbridge, C., Saif, R., Shelton, D. G., Warren, W. C., Wasim, M. & Lyons, L. A., Jan 1 2018, In : Scientific Reports. 8, 1

Research output: Contribution to journalArticle

11 Scopus citations

Author Correction: Applications and efficiencies of the first cat 63K DNA array (Scientific Reports DOI: 10.1038/s41598-018-25438-0)

Gandolfi, B., Alhaddad, H., Abdi, M., Bach, L. H., Creighton, E. K., Davis, B. W., Decker, J. E., Dodman, N. H., Grahn, J. C., Grahn, R. A., Haase, B., Haggstrom, J., Hamilton, M. J., Helps, C. R., Kurushima, J. D., Lohi, H., Longeri, M., Malik, R., Meurs, K. M., Montague, M. J. & 11 others, Mullikin, J. C., Murphy, W. J., Nilson, S. M., Pedersen, N. C., Peterson, C. B., Rusbridge, C., Saif, R., Shelton, G. D., Warren, W. C., Wasim, M. & Lyons, L. A., Dec 1 2018, In : Scientific Reports. 8, 1, 8746.

Research output: Contribution to journalComment/debate

Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq

Watanabe, R., Eckstrand, C., Liu, H. & Pedersen, N. C., Aug 7 2018, In : Veterinary Research. 49, 1, 81.

Research output: Contribution to journalArticle

4 Scopus citations

First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data

Genova, F., Longeri, M., Lyons, L. A., Bagnato, A., Gandolfi, B., Aberdein, D., Alves, P. C., Barsh, G. S., Beale, H. C., Bergström, T. F., Boyko, A. R., Brockman, J. A., Castelhano, M. G., Chan, P. P., Davis, B. W., Distl, O., Dodman, N. H., Matthew Ellinwood, N., Fogle, J. E., Forman, O. P. & 32 others, Garrick, D. J., Häggström, J., Helps, C. R., Hytönen, M. K., Ibrahim, D. M., Kaukonen, M., Kaelin, C. B., Leclerc, E., Lear, T. L., Leeb, T., Lohi, H., Lupiáñez, D. G., Magnuson, M. A., Malik, R., Montague, M. J., Munday, J. S., Murphy, W. J., Ostrander, E. A., Pedersen, N. C., Petersen-Jones, S. M., Rothschild, M. F., Shapiro, B., Stern, J. A., Swanson, W. F., Terio, K. A., Todhunter, R. J., Ueda, Y., Warren, W. C., Wilcox, E. A., Wildschutte, J. H., Ginns, E. I. & Strillacci, M. G., Dec 10 2018, In : BMC Genomics. 19, 1, 895.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies

Murphy, B. G., Perron, M., Murakami, E., Bauer, K., Park, Y., Eckstrand, C., Liepnieks, M. & Pedersen, N. C., Jun 1 2018, In : Veterinary Microbiology. 219, p. 226-233 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2017

A FAS-ligand variant associated with autoimmune lymphoproliferative syndrome in cats

Aberdein, D., Munday, J. S., Gandolfi, B., Dittmer, K. E., Malik, R., Garrick, D. J., Lyons, L. A., 99 Lives Consortium, L. C., Alves, P. C., Barsh, G. S., Beale, H. C., Boyko, A. R., Castelhano, M. G., Chan, P., Ellinwood, N. M., Helps, C. R., Kaelin, C. B., Leeb, T., Lohi, H., Longeri, M. & 8 others, Montague, M. J., Murphy, W. J., Pedersen, N. C., Rothschild, M. F., Swanson, W. F., Terio, K. A., Todhunter, R. J. & Warren, W. C., Feb 1 2017, In : Mammalian Genome. 28, 1-2, p. 47-55 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Early-Onset Progressive Retinal Atrophy Associated with an IQCB1 Variant in African Black-Footed Cats (Felis nigripes)

Oh, A., Pearce, J. W., Gandolfi, B., Creighton, E. K., Suedmeyer, W. K., Selig, M., Bosiack, A. P., Castaner, L. J., Whiting, R. E. H., Belknap, E. B., Lyons, L. A., Aderdein, D., Alves, P. C., Barsh, G. S., Beale, H. C., Boyko, A. R., Castelhano, M. G., Chan, P., Ellinwood, N. M., Garrick, D. J. & 15 others, Helps, C. R., Kaelin, C. B., Leeb, T., Lohi, H., Longeri, M., Malik, R., Montague, M. J., Munday, J. S., Murphy, W. J., Pedersen, N. C., Rothschild, M. F., Swanson, W. F., Terio, K. A., Todhunter, R. J. & Warren, W. C., Mar 21 2017, In : Scientific Reports. 7, 43918.

Research output: Contribution to journalArticle

11 Scopus citations

Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis

Pedersen, N. C., Kim, Y., Liu, H., Galasiti Kankanamalage, A. C., Eckstrand, C., Groutas, W. C., Bannasch, M., Meadows, J. M. & Chang, K. O., Sep 1 2017, (Accepted/In press) In : Journal of Feline Medicine and Surgery.

Research output: Contribution to journalArticle

26 Scopus citations

Infections caused by lentivirinae

Torten, M. & Pedersen, N. C., Jan 1 2017, Handbook of Zoonoses, Second Edition, Section B: Viral Zoonoses. CRC Press, p. 517-527 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Precision Medicine in Cats: Novel Niemann-Pick Type C1 Diagnosed by Whole-Genome Sequencing

and 99 Lives Consortium, Mar 1 2017, In : Journal of Veterinary Internal Medicine. 31, 2, p. 539-544 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016
6 Scopus citations

Polymorphisms in ERAP1 and ERAP2 are shared by Caninae and segregate within and between random- and pure-breeds of dogs

Pedersen, N. C., Dhanota, J. K. & Liu, H., Oct 15 2016, In : Veterinary Immunology and Immunopathology. 179, p. 46-57 12 p.

Research output: Contribution to journalArticle

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

Kim, Y., Liu, H., Galasiti Kankanamalage, A. C., Weerasekara, S., Hua, D. H., Groutas, W. C., Chang, K. O. & Pedersen, N. C., Mar 1 2016, In : PLoS Pathogens. 12, 3, e1005531.

Research output: Contribution to journalArticle

40 Scopus citations
5 Scopus citations
2015

Bartonella infection among cats adopted from a San Francisco shelter, revisited

Fleischman, D. A., Chomel, B. B., Kasten, R. W., Stuckey, M. J., Scarlet, J., Liu, H., Boulouis, H. J., Haddad, N. & Pedersen, N. C., 2015, In : Applied and Environmental Microbiology. 81, 18, p. 6446-6450 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
27 Scopus citations

Understanding genetics: why should vets care?

Jones, B. R., Little, S., Lyons, L. A., Malik, R., Nicholas, F., O’Brien, D. P. & Pedersen, N. C., Mar 25 2015, In : Journal of Feline Medicine and Surgery. 17, 3, p. 201-202 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations
2014

An update on feline infectious peritonitis: Diagnostics and therapeutics

Pedersen, N. C., 2014, In : Veterinary Journal. 201, 2, p. 133-141 9 p.

Research output: Contribution to journalReview article

51 Scopus citations

An update on feline infectious peritonitis: Virology and immunopathogenesis

Pedersen, N. C., 2014, In : Veterinary Journal. 201, 2, p. 123-132 10 p.

Research output: Contribution to journalReview article

65 Scopus citations

Genome-wide association and linkage analyses localize a progressive retinal atrophy locus in Persian cats

Alhaddad, H., Gandolfi, B., Grahn, R. A., Rah, H. C., Peterson, C. B., Maggs, D. J., Koehler, K. G., Pedersen, N. C. & Lyons, L. A., 2014, In : Mammalian Genome. 25, 7-8, p. 354-362 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

The influence of age and genetics on natural resistance to experimentally induced feline infectious peritonitis

Pedersen, N. C., Liu, H., Gandolfi, B. & Lyons, L. A., Nov 15 2014, In : Veterinary Immunology and Immunopathology. 162, 1-2, p. 33-40 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV

Wadford, D. A., Kauffman, R. C., Deere, J. D., Aoki, S. T., Stanton, R. A., Higgins, J., Van Rompay, K. K. A., Villalobos, A., Nettles, J. H., Schinazi, R. F., Pedersen, N. C. & North, T. W., Jan 31 2014, In : PLoS One. 9, 1, e86997.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Genetic susceptibility to feline infectious peritonitis in Birman cats

Golovko, L., Lyons, L. A., Liu, H., Sørensen, A., Wehnert, S. & Pedersen, N. C., Jul 2013, In : Virus Research. 175, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

MHC class II association study in eight breeds of dog with hypoadrenocorticism

Massey, J., Boag, A., Short, A. D., Scholey, R. A., Henthorn, P. S., Littman, M. P., Husebye, E., Catchpole, B., Pedersen, N. C., Mellersh, C. S., Ollier, W. E. R. & Kennedy, L. J., Apr 2013, In : Immunogenetics. 65, 4, p. 291-297 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Simple recessive mutation in ENAM is associated with amelogenesis imperfecta in Italian Greyhounds

Gandolfi, B., Liu, H., Griffioen, L. & Pedersen, N. C., Aug 2013, In : Animal Genetics. 44, 5, p. 569-578 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
21 Scopus citations
55 Scopus citations
2012

Feline infectious peritonitis: Role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats

Pedersen, N. C., Liu, H., Scarlett, J., Leutenegger, C. M., Golovko, L., Kennedy, H. & Kamal, F. M., Apr 2012, In : Virus Research. 165, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

57 Scopus citations

Genetic characterization of healthy and sebaceous adenitis affected Standard Poodles from the United States and the United Kingdom

Pedersen, N. C., Liu, H., Mclaughlin, B. & Sacks, B., Jul 2012, In : Tissue Antigens. 80, 1, p. 46-57 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
13 Scopus citations
2011
3 Scopus citations

Expanded dog leukocyte antigen (DLA) single nucleotide polymorphism (SNP) genotyping reveals spurious class II associations

Safra, N., Pedersen, N. C., Wolf, Z., Johnson, E. G., Liu, H. W., Hughes, A. M., Young, A. & Bannasch, D. L., Aug 2011, In : Veterinary Journal. 189, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Phylogenetic distinctiveness of Middle Eastern and Southeast Asian village dog Y chromosomes illuminates dog origins

Brown, S. K., Pedersen, N. C., Jafarishorijeh, S., Bannasch, D. L., Ahrens, K. D., Wu, J. T., Okon, M. & Sacks, B., Dec 14 2011, In : PLoS One. 6, 12, e28496.

Research output: Contribution to journalArticle

46 Scopus citations
2010

Localization of canine brachycephaly using an across breed mapping approach

Bannasch, D. L., Young, A., Myers, J., Truvé, K., Dickinson, P. J., Gregg, J., Davis, R., Bongcam-Rudloff, E., Webster, M. T., Lindblad-Toh, K. & Pedersen, N. C., Mar 10 2010, In : PLoS One. 5, 3, e9632.

Research output: Contribution to journalArticle

65 Scopus citations

Necrotizing meningoencephalitis of Pug Dogs associates with dog leukocyte antigen class II and resembles acute variant forms of multiple sclerosis

Greer, K. A., Wong, A. K., Liu, H., Famula, T. R., Pedersen, N. C., Ruhe, A., Wallace, M. & Neff, M. W., Aug 2010, In : Tissue Antigens. 76, 2, p. 110-118 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
2009

A review of feline infectious peritonitis virus infection: 1963-2008

Pedersen, N. C., Apr 2009, In : Journal of Feline Medicine and Surgery. 11, 4, p. 225-258 34 p.

Research output: Contribution to journalReview article

227 Scopus citations

Significance of coronavirus mutants in feces and diseased tissues of cats suffering from feline infectious peritonitis

Pedersen, N. C., Liu, H., Dodd, K. A. & Pesavento, P., Aug 26 2009, In : Viruses. 1, 2, p. 166-184 19 p.

Research output: Contribution to journalArticle

71 Scopus citations
2008

Pathogenesis of feline enteric coronavirus infection

Pedersen, N. C., Allen, C. E. & Lyons, L. A., Dec 2008, In : Journal of Feline Medicine and Surgery. 10, 6, p. 529-541 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

The ascent of cat breeds: Genetic evaluations of breeds and worldwide random-bred populations

Lipinski, M. J., Froenicke, L., Baysac, K. C., Billings, N. C., Leutenegger, C. M., Levy, A. M., Longeri, M., Niini, T., Ozpinar, H., Slater, M. R., Pedersen, N. C. & Lyons, L. A., Jan 2008, In : Genomics. 91, 1, p. 12-21 10 p.

Research output: Contribution to journalArticle

95 Scopus citations
2007

A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens

Shen, X., Leutenegger, C. M., Cole, K. S., Pedersen, N. C. & Sparger, E. E., Oct 2007, In : Journal of General Virology. 88, 10, p. 2793-2799 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

An international parentage and identification panel for the domestic cat (Felis catus)

Lipinski, M. J., Amigues, Y., Blasi, M., Broad, T. E., Cherbonnel, C., Cho, G. J., Corley, S., Daftari, P., Delattre, D. R., Dileanis, S., Flynn, J. M., Grattapaglia, D., Guthrie, A., Harper, C., Karttunen, P. L., Kimura, H., Lewis, G. M., Longeri, M., Meriaux, J. C., Morita, M. & 11 others, Morrin-O'Donnell, R. C., Niini, T., Pedersen, N. C., Perrotta, G., Polli, M., Rittler, S., Schubbert, R., Strillacci, M. G., Van Haeringen, H., Van Haeringen, W. & Lyons, L. A., Aug 2007, In : Animal Genetics. 38, 4, p. 371-377 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) mutations associated with the domestic cat AB blood group

Bighignoli, B., Niini, T., Grahn, R. A., Pedersen, N. C., Millon, L. V., Polli, M., Longeri, M. & Lyons, L. A., Jun 6 2007, In : BMC Genetics. 8, 27.

Research output: Contribution to journalArticle

47 Scopus citations