Michael A Rogawski, MD; PhD

Professor

  • 17161 Citations
  • 72 h-Index
1973 …2020

Research output per year

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Research Output

2012

Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine

Zolkowska, D., Banks, C. N., Dhir, A., Inceoglu, B., Sanborn, J. R., McCoy, M. R., Bruun, D. A., Hammock, B. D., Lein, P. J. & Rogawski, M. A., May 1 2012, In : Journal of Pharmacology and Experimental Therapeutics. 341, 2, p. 435-446 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Clustered burst firing in FMR1 premutation hippocampal neurons: Amelioration with allopregnanolone

Cao, Z., Hulsizer, S., Tassone, F., Tang, H. T., Hagerman, R. J., Rogawski, M. A., Hagerman, P. J. & Pessah, I. N., Jul 2012, In : Human Molecular Genetics. 21, 13, p. 2923-2935 13 p., dds118.

Research output: Contribution to journalArticle

57 Scopus citations

Compromised function in the Nav1.2 Dravet syndrome mutation R1312T

Lossin, C., Shi, X., Rogawski, M. A. & Hirose, S., Sep 2012, In : Neurobiology of Disease. 47, 3, p. 378-384 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

How theories evolved concerning the mechanism of action of barbiturates.

Löscher, W. & Rogawski, M. A., Dec 2012, In : Epilepsia. 53 Suppl 8, p. 12-25 14 p.

Research output: Contribution to journalArticle

89 Scopus citations

Mechanisms of action of antiseizure drugs

Porter, R. J., Dhir, A., Macdonald, R. L. & Rogawski, M. A., 2012, In : Handbook of Clinical Neurology. 108, p. 664-681 18 p.

Research output: Contribution to journalArticle

38 Scopus citations

Mechanisms of action of antiseizure drugs.

Porter, R. J., Dhir, A., Macdonald, R. L. & Rogawski, M. A., 2012, In : Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn. 108, p. 663-681 19 p.

Research output: Contribution to journalArticle

Propofol hemisuccinate suppresses cortical spreading depression

Dhir, A., Lossin, C. & Rogawski, M. A., Apr 11 2012, In : Neuroscience Letters. 514, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Role of neurosteroids in the anticonvulsant activity of midazolam

Dhir, A. & Rogawski, M. A., Apr 2012, In : British Journal of Pharmacology. 165, 8, p. 2684-2691 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
31 Scopus citations
2011

11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis

Kaminski, R. M. & Rogawski, M. A., Jul 2011, In : Neuropharmacology. 61, 1-2, p. 133-137 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

A new policy for disclosure of competing interests

Rogawski, M. A., Jan 2011, In : Epilepsy Currents. 11, 1, p. 7-8 2 p.

Research output: Contribution to journalArticle

Disclosure of clinical trial results when product development is abandoned

Rogawski, M. A. & Federo, H. J., Sep 28 2011, In : Science Translational Medicine. 3, 102, 102cm29.

Research output: Contribution to journalArticle

7 Scopus citations

Revisiting AMPA receptors as an antiepileptic drug target

Rogawski, M. A., Mar 2011, In : Epilepsy Currents. 11, 2, p. 56-63 8 p.

Research output: Contribution to journalArticle

216 Scopus citations

Seizure protection by intrapulmonary delivery of propofol hemisuccinate

Dhir, A., Zolkowska, D., Murphy, R. B. & Rogawski, M. A., Jan 2011, In : Journal of Pharmacology and Experimental Therapeutics. 336, 1, p. 215-222 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Treatment of infantile spasms: Emerging insights from clinical and basic science perspectives

Stafstrom, C. E., Arnason, B. G. W., Baram, T. Z., Catania, A., Cortez, M. A., Glauser, T. A., Pranzatelli, M. R., Riikonen, R., Rogawski, M. A., Shinnar, S. & Swann, J. W., Nov 2011, In : Journal of Child Neurology. 26, 11, p. 1411-1421 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
2010

Anticonvulsant and proconvulsant actions of 2-deoxy-d-glucose

Gasior, M., Yankura, J., Hartman, A. L., French, A. & Rogawski, M. A., 2010, In : Epilepsia. 51, 8, p. 1385-1394 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model

Reddy, D. S. & Rogawski, M. A., May 2010, In : Epilepsy Research. 89, 2-3, p. 254-260 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

"Jasper's basic mechanisms of the epilepsies" workshop

Noebels, J. L., Avoli, M., Rogawski, M. A., Olsen, R. & Delgado-Escueta, A. V., Dec 2010, In : Epilepsia. 51, SUPPL. 5, p. 1-5 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Migraine and epilepsy: Shared mechanisms?

Rogawski, M. A., Dec 2010, In : Epilepsia. 51, SUPPL. 5, p. 80 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Neurosteroid replacement therapy for catamenial epilepsy

Reddy, D. S. & Rogawski, M. A., Jan 1 2010, Epilepsy: Mechanisms, Models, and Translational Perspectives. CRC Press, p. 501-513 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurosteroids as endogenous regulators of seizure susceptibility and use in the treatment of epilepsy

Reddy, D. S. & Rogawski, M. A., Dec 2010, In : Epilepsia. 51, SUPPL. 5, p. 84 1 p.

Research output: Contribution to journalArticle

6 Scopus citations

Neurotherapeutics to publish primary research papers

Faden, A. I., Bakshi, R. & Rogawski, M. A., Jul 2010, In : Neurotherapeutics. 7, 3, p. 229 1 p.

Research output: Contribution to journalArticle

Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466

Fritsch, B., Stott, J. J., Joelle Donofrio, J. & Rogawski, M. A., 2010, In : Epilepsia. 51, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

42 Scopus citations
2009

17β-Nitro-5α-androstan-3α-ol and its 3β-methyl derivative: Neurosteroid analogs with potent anticonvulsant and anxiolytic activities

Runyon, S. P., Orr, M., Navarro, H. A., Kepler, J. A., Rogawski, M. A., Kaminski, R. M. & Cook, C. E., Sep 1 2009, In : European Journal of Pharmacology. 617, 1-3, p. 68-73 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Advances in the application of technology to epilepsy: The CIMIT/NIO epilepsy innovation summit

Schachter, S. C., Guttag, J., Schiff, S. J., Schomer, D. L., Akhtari, M., Bailey, E. M., Baptiste, S. L., Barkley, G. L., Beggs, J. M., Béland, R., Besio, W., Binder, D. K., Bonato, P., Bromfield, E., Brunner, P., Carlson, C., Cash, S. S., Cole, A. J., Commowick, O., Devinsky, O. & 55 others, Doyle, W. K., Dunseath, R., Engel, J. J., Eskandar, E., Fregni, F., Frei, M. G., French, J., Gale, K., Gallagher, A., Graves, N., Gross, R. E., Guttag, J., Halgren, E., Hochberg, L., Hsu, D., Hsu, M., Iasemidis, L. D., Irazoqui, P., Koka, K., Kuzniecky, R., Lassonde, M., Lepore, F., Ludvig, N., Madsen, J., Mancinelli, C., McGlone, F., Medveczky, G., Medvedev, A. V., Morrell, M., Nguyen, D. K., Osorio, I., Pang, T., Patel, S., Patritti, B., Potter, S. M., Rickus, J., Ritaccio, A. L., Rogawski, M. A., Rolston, J. D., Rotenberg, A., Rothman, S. M., Sackellares, J. C., Schachter, S. C., Schalk, G., Schiff, S. J., Shoeb, A. H., Schomer, D. L., Strangman, G. E., Tang, H. M., Terry, R. S., Thesen, T., Truccolo, W., Ulbert, I., Warfield, S. & Zhang, Q., Sep 2009, In : Epilepsy and Behavior. 16, 1, p. 3-46 44 p.

Research output: Contribution to journalArticle

27 Scopus citations

Convection-Enhanced Delivery in the Treatment of Epilepsy

Rogawski, M. A., Apr 2009, In : Neurotherapeutics. 6, 2, p. 344-351 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Neurosteroid Replacement Therapy for Catamenial Epilepsy

Reddy, D. S. & Rogawski, M. A., Apr 2009, In : Neurotherapeutics. 6, 2, p. 392-401 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Neurosteroids and epileptogenesis in the pilocarpine model: Evidence for a relationship between P450scc induction and length of the latent period

Biagini, G., Longo, D., Baldelli, E., Zoli, M., Rogawski, M. A., Bertazzoni, G. & Avoli, M., Jan 2009, In : Epilepsia. 50, SUPPL. 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Nontraditional Epilepsy Treatment Approaches

Rogawski, M. A. & Holmes, G. L., Apr 2009, In : Neurotherapeutics. 6, 2, p. 213-217 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis

Fritsch, B., Qashu, F., Figueiredo, T. H., Aroniadou-Anderjaska, V., Rogawski, M. A. & Braga, M. F. M., Sep 29 2009, In : Neuroscience. 163, 1, p. 415-429 15 p.

Research output: Contribution to journalArticle

39 Scopus citations
45 Scopus citations
2008

Brivaracetam: A rational drug discovery success story

Rogawski, M. A., Aug 26 2008, In : British Journal of Pharmacology. 154, 8, p. 1555-1557 3 p.

Research output: Contribution to journalArticle

43 Scopus citations

Common mechanisms in migraine and epilepsy: A comment - Reply

Rogawski, M. A., Nov 2008, In : Archives of Neurology. 65, 11, p. 1546-1547 2 p.

Research output: Contribution to journalArticle

Common pathophysiologic mechanisms in migraine and epilepsy

Rogawski, M. A., Jun 2008, In : Archives of Neurology. 65, 6, p. 709-714 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

Efficacy of the ketogenic diet in the 6-Hz seizure test

Hartman, A. L., Lyle, M., Rogawski, M. A. & Gasior, M., Feb 2008, In : Epilepsia. 49, 2, p. 334-339 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

Shaltiel, G., Maeng, S., Malkesman, O., Pearson, B., Schloesser, R. J., Tragon, T., Rogawski, M. A., Gasior, M., Luckenbaugh, D., Chen, G. & Manji, H. K., Sep 2008, In : Molecular Psychiatry. 13, 9, p. 858-872 15 p.

Research output: Contribution to journalArticle

121 Scopus citations

New molecular targets for antiepileptic drugs: α2 δ, SV2A, and Kv7/KCNQ/M potassium channels

Rogawski, M. A. & Bazil, C. W., 2008, In : Current Neurology and Neuroscience Reports. 8, 4, p. 345-352 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

The anticonvulsant activity of acetone does not depend upon its metabolites

Gasior, M., Hartman, A. L. & Rogawski, M. A., May 2008, In : Epilepsia. 49, 5, p. 936-937 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
2007

Molecular Targets for Antiepileptic Drug Development

Meldrum, B. S. & Rogawski, M. A., Jan 2007, In : Neurotherapeutics. 4, 1, p. 18-61 44 p.

Research output: Contribution to journalArticle

361 Scopus citations
29 Scopus citations

The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid

Gasior, M., French, A., Joy, M. T., Tang, R. S., Hartman, A. L. & Rogawski, M. A., Apr 2007, In : Epilepsia. 48, 4, p. 793-800 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

The Neuropharmacology of the Ketogenic Diet

Hartman, A. L., Gasior, M., Vining, E. P. G. & Rogawski, M. A., May 2007, In : Pediatric Neurology. 36, 5, p. 281-292 12 p.

Research output: Contribution to journalArticle

186 Scopus citations
2006

Alcohol Withdrawal Seizures

N'Gouemo, P. & Rogawski, M. A., 2006, Models of Seizures and Epilepsy. Elsevier Inc., p. 161-177 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Diverse mechanisms of antiepileptic drugs in the development pipeline

Rogawski, M. A., Jun 2006, In : Epilepsy Research. 69, 3, p. 273-294 22 p.

Research output: Contribution to journalArticle

274 Scopus citations

Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy

Biagini, G., Baldelli, E., Longo, D., Pradelli, L., Zini, I., Rogawski, M. A. & Avoli, M., Oct 2006, In : Experimental Neurology. 201, 2, p. 519-524 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Molecular targets versus models for new antiepileptic drug discovery

Rogawski, M. A., Jan 2006, In : Epilepsy Research. 68, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

115 Scopus citations

Neuroprotective and disease-modifying effects of the ketogenic diet

Gasior, M., Rogawski, M. A. & Hartman, A. L., Sep 2006, In : Behavioural Pharmacology. 17, 5-6, p. 431-439 9 p.

Research output: Contribution to journalArticle

242 Scopus citations

Support for the NIH public access policy [3]

Rogawski, M. A. & Suber, P., Sep 15 2006, In : Science. 313, 5793, p. 1572 1 p.

Research output: Contribution to journalArticle

Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models

Motamedi, G. K., Salazar, P., Smith, E. L., Lesser, R. P., Webber, W. R. S., Ortinski, P. I., Vicini, S. & Rogawski, M. A., Aug 2006, In : Epilepsy Research. 70, 2-3, p. 200-210 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

The pheromone androstenol (5α-androst-16-en-3α-ol) is a neurosteroid positive modulator of GABAa receptors

Kaminski, R. M., Marini, H., Ortinski, P. I., Vicini, S. & Rogawski, M. A., May 2006, In : Journal of Pharmacology and Experimental Therapeutics. 317, 2, p. 694-703 10 p.

Research output: Contribution to journalArticle

26 Scopus citations