Mel Campbell

Associate Adjunct Professor

  • 545 Citations
  • 15 h-Index
1994 …2020

Research output per year

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Research Output

  • 545 Citations
  • 15 h-Index
  • 26 Article
  • 1 Review article
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Article
2020

HIV-1 tat interacts with a Kaposi's sarcoma-associated herpesvirus reactivation-upregulated antiangiogenic long noncoding RNA, LINC00313, and antagonizes its function

Yang, W. S., Lin, T. Y., Chang, L., Yeh, W. W., Huang, S. C., Chen, T. Y., Hsieh, Y. T., Chen, S. T., Li, W. C., Pan, C. C., Campbell, M., Yen, C. H., Chen, Y. M. A. & Chang, P. C., Feb 1 2020, In : Journal of Virology. 94, 3, e01280-19.

Research output: Contribution to journalArticle

Open Access
2018

HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer

Chang, Y. T., Lin, T. P., Tang, J. T., Campbell, M., Luo, Y. L., Lu, S. Y., Yang, C. P., Cheng, T. Y., Chang, C. H., Liu, T. T., Lin, C. H., Kung, H. J., Pan, C. C. & Chang, P. C., Oct 1 2018, In : Cancer Letters. 433, p. 43-52 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

In vitro SUMOylation assay to study SUMO E3 ligase activity

Yang, W. S., Campbell, M., Kung, H. J. & Chang, P. C., Jan 29 2018, In : Journal of Visualized Experiments. 2018, 131, e56629.

Research output: Contribution to journalArticle

1 Scopus citations

KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation

Campbell, M., Watanabe, T., Nakano, K., Davis, R. R., Lyu, Y., Tepper, C. G., Durbin-Johnson, B., Fujimuro, M. & Izumiya, Y., Dec 1 2018, In : Nature Communications. 9, 1, 02089.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Kaposi's sarcoma-associated herpesvirus hijacks RNA polymerase II to create a viral transcriptional factory

Chen, C. P., Lyu, Y., Chuang, F., Nakano, K., Izumiya, C., Jin, D., Campbell, M. & Izumiya, Y., Jun 1 2017, In : Journal of Virology. 91, 11, e02491-16.

Research output: Contribution to journalArticle

11 Scopus citations

MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells

Lin, Y. C., Chang, Y. T., Campbell, M., Lin, T. P., Pan, C. C., Lee, H. C., Shih, J. C. & Chang, P. C., Apr 12 2017, In : Scientific reports. 7, 46338.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma

Zhou, F., Shimoda, M., Olney, L., Lyu, Y., Tran, K., Jiang, G., Nakano, K., Davis, R. R., Tepper, C. G., Maverakis, E., Campbell, M., Li, Y., Dandekar, S. & Izumiya, Y., Nov 1 2017, In : Molecular Cancer Therapeutics. 16, 11, p. 2627-2638 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer

Chang, Y. T., Lin, T. P., Campbell, M., Pan, C. C., Lee, S. H., Lee, H. C., Yang, M. H., Kung, H. J. & Chang, P. C., Mar 3 2017, In : Scientific Reports. 7, 42795.

Research output: Contribution to journalArticle

15 Scopus citations

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication

Yang, W. S., Campbell, M. & Chang, P. C., Feb 2017, In : PLoS pathogens. 13, 2, e1006216.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

ZIC2 is essential for maintenance of latency and is a target of an immediate early protein during Kaposi's sarcoma-associated herpesvirus lytic reactivation

Lyu, Y., Nakano, K., Davis, R. R., Tepper, C. G., Campbell, M. & Izumiya, Y., Nov 1 2017, In : Journal of Virology. 91, 21, e00980-17.

Research output: Contribution to journalArticle

4 Scopus citations
2016

KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis

Wang, L. Y., Hung, C. L., Chen, Y. R., Yang, J. C., Wang, J., Campbell, M., Izumiya, Y., Chen, H. W., Wang, W. C., Ann, D. K. & Kung, H. J., Sep 13 2016, In : Cell Reports. 16, 11, p. 3016-3027 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Lin, T. P., Chang, Y. T., Lee, S. Y., Campbell, M., Wang, T. C., Shen, S. H., Chung, H. J., Chang, Y. H., Chiu, A. W., Pan, C. C., Lin, C. H., Chu, C. Y., Kung, H. J., Cheng, C. Y. & Chang, P. C., May 1 2016, In : Oncotarget. 7, 18, p. 26137-26151 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
2015

K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation

Yang, W. S., Hsu, H. W., Campbell, M., Cheng, C. Y. & Chang, P. C., Jul 1 2015, In : PLoS pathogens. 11, 7, e1005051.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

PRMT4-mediated arginine methylation negatively regulates retinoblastoma tumor suppressor protein and promotes E2F-1 dissociation

Kim, K. Y., Wang, D. H., Campbell, M., Huerta, S. B., Shevchenko, B., Izumiya, C. & Izumiyaa, Y., Jan 1 2015, In : Molecular and Cellular Biology. 35, 1, p. 238-248 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2014

A lytic viral long noncoding RNA modulates the function of a latent protein

Campbell, M., Kim, K. Y., Chang, P. C., Huerta, S., Shevchenko, B., Wang, D. H., Izumiya, C., Kung, H. J. & Izumiya, Y., Feb 2014, In : Journal of Virology. 88, 3, p. 1843-1848 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Long non-coding RNA and epigenetic gene regulation of KSHV

Campbell, M., Kung, H. J. & Izumiya, Y., Nov 4 2014, In : Viruses. 6, 11, p. 4165-4177 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Kaposi's sarcoma-Associated herpesvirus (KSHV) latency-Associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A

Kim, K. Y., Huerta, S. B., Izumiya, C., Wang, D. H., Martinez, A., Shevchenko, B., Kung, H. J., Campbell, M. & Izumiya, Y., Jun 2013, In : Journal of Virology. 87, 12, p. 6782-6793 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Kaposi's Sarcoma-Associated Herpesvirus K-Rta Exhibits SUMO-Targeting Ubiquitin Ligase (STUbL) Like Activity and Is Essential for Viral Reactivation

Izumiya, Y., Kobayashi, K., Kim, K. Y., Pochampalli, M., Izumiya, C., Shevchenko, B., Wang, D. H., Huerta, S. B., Martinez, A., Campbell, M. & Kung, H. J., Aug 2013, In : PLoS Pathogens. 9, 8, e1003506.

Research output: Contribution to journalArticle

37 Scopus citations

The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi's sarcoma associated herpesvirus reactivation

Chang, P. C., Cheng, C. Y., Campbell, M., Yang, Y. C., Hsu, H. W., Chang, T. Y., Chu, C. H., Lee, Y. W., Hung, C. L., Lai, S. M., Tepper, C. G., Hsieh, W. P., Wang, H. W., Tang, C. Y., Wang, W. C. & Kung, H. J., Nov 23 2013, In : BMC Genomics. 14, 1, 824.

Research output: Contribution to journalArticle

20 Scopus citations
2012
23 Scopus citations

Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen

Campbell, M., Chang, P. C., Huerta, S., Izumiya, C., Davis, R., Tepper, C. G., Kim, K. Y., Shevchenko, B., Wang, D. H., Jung, J. U., Luciw, P. A., Kung, H. J. & Izumiya, Y., Feb 17 2012, In : Journal of Biological Chemistry. 287, 8, p. 5806-5818 13 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor

Chang, P. C., Fitzgerald, L. D., Hsia, D. A., Izumiya, Y., Wu, C. Y., Hsieh, W. P., Lin, S. F., Campbell, M., Lam, K. S., Luciw, P. A., Tepper, C. G. & Kung, H. J., Apr 2011, In : Journal of Virology. 85, 7, p. 3283-3293 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2010

Kaposi's Sarcoma-associated Herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific

Chang, P. C., Izumiya, Y., Wu, C. Y., Fitzgerald, L. D., Campbell, M., Ellison, T. J., Lam, K. S., Luciw, P. A. & Kung, H. J., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5266-5273 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Multiplex analysis of Src family kinase signaling by microbead suspension arrays

Campbell, M., Lie, W. R., Zhao, J., Hayes, D., Mistry, J., Kung, H. J., Luciw, P. A. & Khan, I. H., Aug 1 2010, In : Assay and Drug Development Technologies. 8, 4, p. 488-496 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
1996
15 Scopus citations
1994

Characterization of the internal promoter of simian foamy viruses

Campbell, M., Renshaw-Gegg, L., Renne, R. & Luciw, P. A., Aug 1994, In : Journal of Virology. 68, 8, p. 4811-4820 10 p.

Research output: Contribution to journalArticle

39 Scopus citations