• 2857 Citations
  • 33 h-Index
1979 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2857 Citations
  • 33 h-Index
  • 75 Article
  • 3 Chapter
  • 2 Editorial
Filter
Article
2018

Exacerbated brain edema in a rat streptozotocin model of hyperglycemic ischemic stroke: Evidence for involvement of blood–brain barrier Na–K–Cl cotransport and Na/H exchange

Yuen, N. Y., Chechneva, O. V., Chen, Y-J., Tsai, Y. C., Little, L. K., Dang, J., Tancredi, D. J., Conston, J., Anderson, S. E. & O'Donnell, M. E., Jan 1 2018, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Histological and cognitive alterations in adult diabetic rats following an episode of juvenile diabetic ketoacidosis: Evidence of permanent cerebral injury

Glaser, N., Sasaki- Russell, J., Cohen, M., Little, C., O'Donnell, M. E. & Sall, J., May 22 2017, In : Neuroscience Letters. 650, p. 161-167 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016
14 Scopus citations

Treatment with the KCa3.1 inhibitor TRAM-34 during diabetic ketoacidosis reduces inflammatory changes in the brain

Glaser, N., Little, C., Lo, W., Cohen, M., Tancredi, D. J., Wulff, H. & O'Donnell, M. E., 2016, (Accepted/In press) In : Pediatric Diabetes.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Blood-brain barrier KCa3.1 Channels: Evidence for a role in brain na uptake and edema in ischemic stroke

Chen, Y-J., Wallace, B. K., Yuen, N., Jenkins, D. P., Wulff, H. & O'Donnell, M. E., Jan 3 2015, In : Stroke. 46, 1, p. 237-244 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Levels of S100B in brain and blood of rats with diabetic ketoacidosis

Glaser, N., Lo, W., Tancredi, D. J., Orgain, M., Puvenna, V., Janigro, D. & O'Donnell, M. E., 2015, In : Brain Research. 1624, p. 536-544 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Blood-brain barrier Na transporters in ischemic stroke

O'Donnell, M. E., 2014, In : Advances in Pharmacology. 71, p. 113-146 34 p.

Research output: Contribution to journalArticle

26 Scopus citations

Brain cell swelling during hypocapnia increases with hyperglycemia or ketosis

Glaser, N., Bundros, A., Anderson, S., Tancredi, D. J., Lo, W., Orgain, M. & O'Donnell, M. E., Nov 1 2014, In : Pediatric Diabetes. 15, 7, p. 484-493 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
23 Scopus citations
2013
40 Scopus citations
2012

Cognitive dysfunction associated with diabetic ketoacidosis in rats

Glaser, N., Anderson, S., Leong, W., Tancredi, D. J. & O'Donnell, M. E., Feb 29 2012, In : Neuroscience Letters. 510, 2, p. 110-114 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effects of hyperglycemia and effects of ketosis on cerebral perfusion, cerebral water distribution, and cerebral metabolism

Glaser, N., Ngo, C., Anderson, S., Yuen, N., Trifu, A. & O'Donnell, M. E., Jul 2012, In : Diabetes. 61, 7, p. 1831-1837 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
24 Scopus citations
2011

Effects of estradiol on ischemic factor-induced astrocyte swelling and AQP4 protein abundance

Rutkowsky, J. M., Wallace, B. K., Wise, P. M. & O'Donnell, M. E., Jul 2011, In : American Journal of Physiology - Cell Physiology. 301, 1

Research output: Contribution to journalArticle

38 Scopus citations

Engaging neuroscience to advance translational research in brain barrier biology

Neuwelt, E. A., Bauer, B., Fahlke, C., Fricker, G., Iadecola, C., Janigro, D., Leybaert, L., Molnár, Z., O'Donnell, M. E., Povlishock, J. T., Saunders, N. R., Sharp, F. R., Stanimirovic, D., Watts, R. J. & Drewes, L. R., Mar 2011, In : Nature Reviews Neuroscience. 12, 3, p. 169-182 14 p.

Research output: Contribution to journalArticle

337 Scopus citations
24 Scopus citations
64 Scopus citations
2010
34 Scopus citations
2009
55 Scopus citations
2008

Cerebral blood flow and cerebral edema in rats with diabetic ketoacidosis

Yuen, N., Anderson, S. E., Glaser, N., Tancredi, D. J. & O'Donnell, M. E., Oct 2008, In : Diabetes. 57, 10, p. 2588-2594 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Hypoxia effects on cell volume and ion uptake of cerebral microvascular endothelial cells

Brillault, J., Lam, T. I., Rutkowsky, J. M., Foroutan, S. & O'Donnell, M. E., Jan 2008, In : American Journal of Physiology - Cell Physiology. 294, 1

Research output: Contribution to journalArticle

42 Scopus citations
19 Scopus citations
2006

Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion

O'Donnell, M. E., Lam, T. I., Tran, L. Q., Foroutan, S. & Anderson, S. E., Oct 18 2006, In : Journal of Cerebral Blood Flow and Metabolism. 26, 10, p. 1234-1249 16 p.

Research output: Contribution to journalArticle

80 Scopus citations
127 Scopus citations
2005
55 Scopus citations

Bumetanide reduces cerebral edema formation in rats with diabetic ketoacidosis

Lam, T. I., Anderson, S. E., Glaser, N. & O'Donnell, M. E., Feb 2005, In : Diabetes. 54, 2, p. 510-516 7 p.

Research output: Contribution to journalArticle

49 Scopus citations
61 Scopus citations

The role of the blood-brain barrier Na-K-2Cl cotransporter in stroke

O'Donnell, M. E., Lam, T. I., Tran, L. & Anderson, S. E., 2005, In : Advances in Experimental Medicine and Biology. 559, p. 67-75 9 p.

Research output: Contribution to journalArticle

24 Scopus citations
2004

Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke

O'Donnell, M. E., Tran, L., Lam, T. I., Liu, X. B. & Anderson, S. E., Sep 2004, In : Journal of Cerebral Blood Flow and Metabolism. 24, 9, p. 1046-1056 11 p.

Research output: Contribution to journalArticle

167 Scopus citations
2001

Expression of aquaporin-1 in human trabecular meshwork cells: Role in resting cell volume

Stamer, W. D., Peppel, K., O'Donnell, M. E., Roberts, B. C., Wu, F. & Epstein, D. L., 2001, In : Investigative Ophthalmology and Visual Science. 42, 8, p. 1803-1811 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Flow-induced expression of endothelial Na-K-Cl cotransport: Dependence on K+ and Cl- channels

Suvatne, J., Barakat, A. I. & O'Donnell, M. E., 2001, In : American Journal of Physiology - Cell Physiology. 280, 1 49-1

Research output: Contribution to journalArticle

30 Scopus citations

Quantitation of Na+-K+-2Cl- cotransport splice variants in human tissues using kinetic polymerase chain reaction

Vibat, C. R. T., Holland, M. J., Kang, J. J., Putney, L. K. & O'Donnell, M. E., Dec 15 2001, In : Analytical Biochemistry. 298, 2, p. 218-230 13 p.

Research output: Contribution to journalArticle

32 Scopus citations
1999

Effects of Na-K-2Cl cotransport regulators on outflow facility in calf and human eyes in vitro

Al-Aswad, L. A., Gong, H., David, L., O'Donnell, M. E., Brandt, J. D., Ryan, W. J., Schroeder, A. & Erickson, K. A., 1999, In : Investigative Ophthalmology and Visual Science. 40, 8, p. 1695-1701 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

How does the trabecular meshwork regulate outflow? Clues from the vascular endothelium

Brandt, J. D. & O'Donnell, M. E., 1999, In : Journal of Glaucoma. 8, 5, p. 328-339 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Intracellular Cl regulates Na-K-Cl cotransport activity in human trabecular meshwork cells

Putney, L. K., Vibat, C. R. T. & O'Donnell, M. E., 1999, In : American Journal of Physiology - Cell Physiology. 277, 3 46-3

Research output: Contribution to journalArticle

21 Scopus citations

Na-K-Cl cotransport in normal and glaucomatous human trabecular meshwork cells

Putney, L. K., Brandt, J. D. & O'Donnell, M. E., Feb 1999, In : Investigative Ophthalmology and Visual Science. 40, 2, p. 425-434 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
1998

Quantitative analysis of Na -K'-2Cl cotransporter rna splice variant transcripts from human tissue

Vibat, C. R. T., Kang, J. J., Holland, M. J. & O'Donnell, M. E., 1998, In : FASEB Journal. 12, 8

Research output: Contribution to journalArticle

Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation

Cai, S., Pestic-Dragovich, L., O'Donnell, M. E., Wang, N., Ingber, D., Elson, E. & De Lanerolle, P., 1998, In : American Journal of Physiology - Cell Physiology. 275, 5 44-5

Research output: Contribution to journalArticle

88 Scopus citations
1997

Effect of cell shrinkage on permeability of cultured bovine aortic endothelia and frog mesenteric capillaries

Kajimura, M., O'Donnell, M. E. & Curry, F. E., Sep 1 1997, In : Journal of Physiology. 503, 2, p. 413-425 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
25 Scopus citations
47 Scopus citations

Molecular characterization of the Na-K-Cl cotransporter of bovine aortic endothelial cells

Yerby, T. R., Vibat, C. R. T., Sun, D., Payne, J. A. & O'Donnell, M. E., Jul 1997, In : American Journal of Physiology - Cell Physiology. 273, 1 42-1

Research output: Contribution to journalArticle

41 Scopus citations
1996
18 Scopus citations
5 Scopus citations

Cloning and characterization of the bovine aortic endothel1al NA-K-CL cotransporter

Yerby, T. R., Pavne, J. A. & O'Donnell, M. E., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

Cloning and characterization of the endothelial cell Na-K-Cl cotransporter

O'Donnell, M. E., Yerby, T. R., Gonsalves, L., Brandt, J. D. & Payne, J. A., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

1 Scopus citations

Dexamethasone increases Na-K-Cl cotransport activity in trabecular meshwork cells

Gonsalves, L., Brandt, J. D. & O'Donnell, M. E., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

1 Scopus citations
1995
55 Scopus citations
64 Scopus citations