Luke Anthony Wittenburg, BS; DVM; PhD

Assistant Professor

  • 283 Citations
  • 8 h-Index
20102019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 283 Citations
  • 8 h-Index
  • 29 Article
  • 1 Review article
Filter
Article
2010

Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer

Wittenburg, L. A., Gustafson, D. L. & Thamm, D. H., Oct 1 2010, In : Clinical Cancer Research. 16, 19, p. 4832-4842 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin

Wittenburg, L. A., Bisson, L., Rose, B. J., Korch, C. & Thamm, D. H., Jan 2011, In : Cancer Chemotherapy and Pharmacology. 67, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2012

A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcoma

Wittenburg, L. A., Ptitsyn, A. A. & Thamm, D. H., Mar 2012, In : Journal of Cellular Biochemistry. 113, 3, p. 773-783 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013
6 Scopus citations

Equine Endometrial Tissue Concentration of Fluconazole Following Oral Administration

Scofield, D. B., Wittenburg, L. A., Ferris, R. A., Gustafson, D. L. & McCue, P. M., Jan 2013, In : Journal of Equine Veterinary Science. 33, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2014

Development of a limited-sampling model for prediction of doxorubicin exposure in dogs

Wittenburg, L. A., Thamm, D. H. & Gustafson, D. L., 2014, In : Veterinary and Comparative Oncology. 12, 2, p. 114-119 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effect of topical naltrexone 0.3% on corneal sensitivity and tear parameters in normal brachycephalic dogs

Arnold, T. S., Wittenburg, L. A. & Powell, C. C., Sep 1 2014, In : Veterinary Ophthalmology. 17, 5, p. 328-333 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Endometrial tissue and blood plasma concentration of ceftiofur and metabolites following intramuscular administration of ceftiofur crystalline free acid to mares

Scofield, D., Black, J., Wittenburg, L. A., Gustafson, D., Ferris, R., Hatzel, J., Traub-Dargatz, J. & Mccue, P., 2014, In : Equine Veterinary Journal. 46, 5, p. 606-610 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

Barnard, R. A., Wittenburg, L. A., Amaravadi, R. K., Gustafson, D. L., Thorburn, A. & Thamm, D. H., 2014, In : Autophagy. 10, 8, p. 1415-1425 11 p.

Research output: Contribution to journalArticle

97 Scopus citations
2015

Pharmacokinetics and bioavailability of orbifloxacin oral suspension in New Zealand white rabbits (oryctolagus cuniculus)

Watson, M. K., Wittenburg, L. A., Bui, C. T., Jarosz, K. A., Gustafson, D. L. & Johnston, M. S., Nov 1 2015, In : American Journal of Veterinary Research. 76, 11, p. 946-951 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban after oral and intravenous administration to cats

Myers, J. A., Wittenburg, L. A., Olver, C. S., Martinez, C. M. & Bright, J. M., 2015, In : American Journal of Veterinary Research. 76, 8, p. 732-738 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Docetaxel accumulates in lymphatic circulation following subcutaneous delivery compared to intravenous delivery in rats

Worley, D. R., Hansen, R. J., Wittenburg, L. A., Chubb, L. S. & Gustafson, D. L., Oct 1 2016, In : Anticancer Research. 36, 10, p. 5071-5078 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Limited sampling pharmacokinetics of subcutaneous ondansetron in healthy geriatric cats, cats with chronic kidney disease, and cats with liver disease

Fitzpatrick, R. L., Wittenburg, L. A., Hansen, R. J., Gustafson, D. L. & Quimby, J. M., Aug 1 2016, In : Journal of Veterinary Pharmacology and Therapeutics. 39, 4, p. 350-355 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse

Colbath, A. C., Wittenburg, L. A., Gold, J. R., McIlwraith, C. W. & Moorman, V. J., Aug 1 2016, In : Veterinary Surgery. 45, 6, p. 798-803 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Anti-inflammatory drugs decrease infection of brain endothelial cells with EHV-1 in vitro

Goehring, L. S., Brandes, K., Ashton, L. V., Wittenburg, L. A., Olea-Popelka, F. J., Lunn, D. P. & Soboll Hussey, G., 2017, (Accepted/In press) In : Equine Veterinary Journal.

Research output: Contribution to journalArticle

1 Scopus citations

Assessment of absorption of transdermal ondansetron in normal research cats

Zajic, L. B., Herndon, A. K., Sieberg, L. G., Caress, A. L., Morgan, P. K., Hansen, R. J., Wittenburg, L. A., Gustafson, D. L. & Quimby, J. M., Dec 1 2017, In : Journal of Feline Medicine and Surgery. 19, 12, p. 1245-1248 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Drug exposure and clinical effect of transdermal mirtazapine in healthy young cats: a pilot study

Benson, K. K., Zajic, L. B., Morgan, P. K., Brown, S. R., Hansen, R. J., Lunghofer, P. J., Wittenburg, L. A., Gustafson, D. L. & Quimby, J. M., Oct 1 2017, In : Journal of Feline Medicine and Surgery. 19, 10, p. 998-1006 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pharmacokinetics of Intrauterine Ciprofloxacin in the Mare and Establishment of Minimum Inhibitory Concentrations for Equine Uterine Bacterial Isolates

Trundell, D. A., Ferris, R. A., Hennet, M. R., Wittenburg, L. A., Gustafson, D. L., Borlee, B. R. & McCue, P. M., Jul 1 2017, In : Journal of Equine Veterinary Science. 54, p. 54-59 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Plasma, subcutaneous tissue and bone concentrations of ceftiofur sodium after regional limb perfusion in horses

Cox, K. S., Nelson, B. B., Wittenburg, L. A. & Gold, J. R., May 1 2017, In : Equine Veterinary Journal. 49, 3, p. 341-344 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Preliminary pharmacokinetics of intravenous and subcutaneous dolasetron and pharmacodynamics of subcutaneous dolasetron in healthy cats

Herndon, A. K., Quimby, J. M., Sieberg, L. G., Davis, L., Caress, A. L., Ligas, S., Hansen, R. J., Wittenburg, L. A. & Gustafson, D. L., Sep 1 2017, (Accepted/In press) In : Journal of Feline Medicine and Surgery.

Research output: Contribution to journalArticle

2018

A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma

Alegre, F., Ormonde, A. R., Snider, K. M., Woolard, K. D., Yu, A. & Wittenburg, L. A., Dec 1 2018, In : PloS one. 13, 12, e0209941.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

In vitro and in vivo activity of liposome-encapsulated curcumin for naturally occurring canine cancers

Withers, S. S., York, D., Johnson, E., Al-Nadaf, S., Skorupski, K. A., Rodriguez, C. O., Burton, J. H., Guerrero, T., Sein, K., Wittenburg, L. & Rebhun, R. B., Jan 1 2018, (Accepted/In press) In : Veterinary and Comparative Oncology.

Research output: Contribution to journalArticle

2 Scopus citations

In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease

Fitzpatrick, R. L., Quimby, J. M., Benson, K. K., Ramirez, D., Sieberg, L. G., Wittenburg, L. A. & Gustafson, D. L., Jan 1 2018, (Accepted/In press) In : Journal of Veterinary Internal Medicine.

Research output: Contribution to journalArticle

1 Scopus citations

Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs

Bartner, L. R., McGrath, S., Rao, S., Hyatt, L. K. & Wittenburg, L. A., Jul 1 2018, In : Canadian Journal of Veterinary Research. 82, 3, p. 178-183 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

PHARMACOKINETICS OF SINGLE-DOSE BUPRENORPHINE, BUTORPHANOL, AND HYDROMORPHONE IN THE DOMESTIC FERRET (MUSTELA PUTORIUS FURO)

Katzenbach, J. E., Wittenburg, L. A., Allweiler, S. I., Gustafson, D. L. & Johnston, M. S., Jan 1 2018, (Accepted/In press) In : Journal of Exotic Pet Medicine.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers

Wittenburg, L. A., Weishaar, K., Ramirez, D. & Gustafson, D. L., Jan 1 2019, In : Veterinary and Comparative Oncology.

Research output: Contribution to journalArticle

2 Scopus citations

Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors

Kirsch, M., Weisse, C., Berent, A., Clifford, C., Leibman, N., Wittenburg, L. A., Solomon, S. B. & Lamb, K., Jul 1 2019, In : Canadian Journal of Veterinary Research. 83, 3, p. 187-196 10 p.

Research output: Contribution to journalArticle

Simultaneous absolute quantitation of ATP-binding cassette transporters in normal dog tissues by signature peptide analysis using a LC/MS/MS method

Wittenburg, L. A., Ramirez, D., Conger, H. & Gustafson, D. L., Feb 1 2019, In : Research in Veterinary Science. 122, p. 93-101 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma

Alegre, F., Ormonde, A. R., Godinez, D. R., Illendula, A., Bushweller, J. H. & Wittenburg, L. A., Jan 1 2019, (Accepted/In press) In : Veterinary and Comparative Oncology.

Research output: Contribution to journalArticle

1 Scopus citations