• 974 Citations
  • 19 h-Index
20072020

Research output per year

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Research Output

2020

Impaired skeletal muscle mitochondrial bioenergetics and physical performance in chronic kidney disease

Kestenbaum, B., Gamboa, J., Liu, S., Ali, A. S., Shankland, E., Jue, T., Giulivi, C., Smith, L. R., Himmelfarb, J., de Boer, I. H., Conley, K. & Roshanravan, B., Mar 12 2020, In : JCI Insight. 5, 5, e133289.

Research output: Contribution to journalArticle

Open Access

Matrix Metalloproteinase 13 from Satellite Cells is Required for Efficient Muscle Growth and Regeneration

Smith, L. R., Kok, H. J., Zhang, B., Chung, D., Spradlin, R. A., Rakoczy, K. D., Lei, H., Boesze-Battaglia, K. & Barton, E. R., Apr 11 2020, In : Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 54, 3, p. 333-353 21 p.

Research output: Contribution to journalArticle

Open Access
2019

Constricted migration modulates stem cell differentiation

Smith, L. R., Irianto, J., Xia, Y., Pfeifer, C. R. & Discher, D. E., Jul 22 2019, In : Molecular biology of the cell. 30, 16, p. 1985-1999 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Contribution of extracellular matrix components to the stiffness of skeletal muscle contractures in patients with cerebral palsy

Smith, L. R., Pichika, R., Meza, R. C., Gillies, A. R., Baliki, M. N., Chambers, H. G. & Lieber, R. L., Jan 1 2019, (Accepted/In press) In : Connective Tissue Research.

Research output: Contribution to journalArticle

1 Scopus citations

Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin

Barton, E. R., Pham, J., Brisson, B. K., Park, S. H., Smith, L. R., Liu, M., Tian, Z., Hammers, D. W., Vassilakos, G. & Sweeney, H. L., Oct 1 2019, In : Muscle and Nerve. 60, 4, p. 464-473 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle

Xia, Y., Pfeifer, C. R., Zhu, K., Irianto, J., Liu, D., Pannell, K., Chen, E. J., Dooling, L. J., Tobin, M. P., Wang, M., Ivanovska, I. L., Smith, L. R., Greenberg, R. A. & Discher, D. E., Aug 5 2019, In : The Journal of cell biology. 218, 8, p. 2545-2563 19 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Skeletal muscle explants: ex-vivo models to study cellular behavior in a complex tissue environment

Smith, L. R. & Meyer, G. A., Jan 1 2019, (Accepted/In press) In : Connective Tissue Research.

Research output: Contribution to journalArticle

2018

Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces

Ban, E., Franklin, J. M., Nam, S., Smith, L. R., Wang, H., Wells, R. G., Chaudhuri, O., Liphardt, J. T. & Shenoy, V. B., Jan 23 2018, In : Biophysical Journal. 114, 2, p. 450-461 12 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors

Xia, Y., Ivanovska, I. L., Zhu, K., Smith, L., Irianto, J., Pfeifer, C. R., Alvey, C. M., Ji, J., Liu, D., Cho, S., Bennett, R. R., Liu, A. J., Greenberg, R. A. & Discher, D. E., Nov 1 2018, In : Journal of Cell Biology. 217, 11, p. 3796-3808 13 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Regulation of fibrosis in muscular dystrophy

Smith, L. R. & Barton, E. R., Aug 2018, In : Matrix Biology. 68-69, p. 602-615 14 p.

Research output: Contribution to journalReview article

25 Scopus citations

Stem cell differentiation is regulated by extracellular matrix mechanics

Smith, L. R., Cho, S. & Discher, D. E., Jan 2018, In : Physiology. 33, 1, p. 16-25 10 p.

Research output: Contribution to journalReview article

50 Scopus citations
2017

Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer

Discher, D. E., Smith, L., Cho, S., Colasurdo, M., Garciá, A. J. & Safran, S., May 22 2017, In : Annual Review of Biophysics. 46, p. 295-315 21 p.

Research output: Contribution to journalReview article

32 Scopus citations
27 Scopus citations

SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors

Alvey, C. M., Spinler, K. R., Irianto, J., Pfeifer, C. R., Hayes, B., Xia, Y., Cho, S., Dingal, P. C. P. D., Hsu, J., Smith, L., Tewari, M. & Discher, D. E., Jul 24 2017, In : Current Biology. 27, 14, p. 2065-2077.e6

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
2016

Increased collagen cross-linking is a signature of dystrophin-deficient muscle

Smith, L. R., Hammers, D. W., Sweeney, H. L. & Barton, E. R., Jul 1 2016, In : Muscle and Nerve. 54, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2015

Masticatory muscles of mouse do not undergo atrophy in space

Philippou, A., Minozzo, F. C., Spinazzola, J. M., Smith, L. R., Lei, H., Rassier, D. E. & Barton, E. R., Jul 1 2015, In : FASEB Journal. 29, 7, p. 2769-2779 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014
49 Scopus citations

Influencing the secretion of myogenic factors from mesenchymal stem cells

Smith, L. R., Aug 13 2014, In : Stem Cell Research and Therapy. 5, 4, 96.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

SMASH - semi-automatic muscle analysis using segmentation of histology: A MATLAB application

Smith, L. R. & Barton, E. R., Nov 27 2014, In : Skeletal Muscle. 4, 1, 21.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Targeting latent TGFβ release in muscular dystrophy

Ceco, E., Bogdanovich, S., Gardner, B., Miller, T., DeJesus, A., Earley, J. U., Hadhazy, M., Smith, L. R., Barton, E. R., Molkentin, J. D. & McNally, E. M., Oct 22 2014, In : Science Translational Medicine. 6, 259, p. 259ra144

Research output: Contribution to journalArticle

20 Scopus citations
2013

Matrix metalloproteinase 13 is a new contributor to skeletal muscle regeneration and critical for myoblast migration

Lei, H., Leong, D., Smith, L. R. & Barton, E. R., Sep 1 2013, In : American Journal of Physiology - Cell Physiology. 305, 5, p. C529-C538

Research output: Contribution to journalArticle

29 Scopus citations

Reduced satellite cell population may lead to contractures in children with cerebral palsy

Smith, L. R., Chambers, H. G. & Lieber, R. L., Jan 1 2013, In : Developmental Medicine and Child Neurology. 55, 3, p. 264-270 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Skeletal muscle changes due to cerebral palsy

Lieber, R. L. & Smith, L. R., Sep 1 2013, Cerebral Palsy in Infancy: Targeted Activity to Optimize Early Growth and Development. Elsevier Ltd., p. 135-155 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Systems analysis of biological networks in skeletal muscle function

Smith, L. R., Meyer, G. & Lieber, R. L., Jan 1 2013, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 5, 1, p. 55-71 17 p.

Research output: Contribution to journalReview article

34 Scopus citations
2012

Corrigendum to "Muscle extracellular matrix applies a transverse stress on fibers with axial strain" [J. Biomech. 44 (2011) 1618-1620]

Smith, L. R., Fowler-Gerace, L. H. & Lieber, R. L., Jan 3 2012, In : Journal of Biomechanics. 45, 1, 1 p.

Research output: Contribution to journalComment/debate

Response to Letter to the Editor: 'Poisson's ratios in anisotropic materials at finite strains; comment on short communication by Smith et al. (2011)'

Smith, L. R., Fowler-Gerace, L. & Lieber, R. L., Jun 26 2012, In : Journal of Biomechanics. 45, 10, p. 1859-1860 2 p.

Research output: Contribution to journalLetter

Transcriptional abnormalities of hamstring muscle contractures in children with cerebral palsy

Smith, L. R., Chambers, H. G., Subramaniam, S. & Lieber, R. L., Aug 16 2012, In : PloS one. 7, 8, e40686.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations
2011

Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length

Smith, L. R., Lee, K. S., Ward, S. R., Chambers, H. G. & Lieber, R. L., May 1 2011, In : Journal of Physiology. 589, 10, p. 2625-2639 15 p.

Research output: Contribution to journalArticle

212 Scopus citations

Method for decellularizing skeletal muscle without detergents or proteolytic enzymes

Gillies, A. R., Smith, L. R., Lieber, R. L. & Varghese, S., Apr 1 2011, In : Tissue Engineering - Part C: Methods. 17, 4, p. 383-389 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Muscle extracellular matrix applies a transverse stress on fibers with axial strain

Smith, L. R., Gerace-Fowler, L. & Lieber, R. L., May 17 2011, In : Journal of Biomechanics. 44, 8, p. 1618-1620 3 p.

Research output: Contribution to journalArticle

24 Scopus citations
2009

Cooperative cross-bridge activation of thin filaments contributes to the Frank-Starling mechanism in cardiac muscle

Smith, L., Tainter, C., Regnier, M. & Martyn, D. A., Jan 1 2009, In : Biophysical Journal. 96, 9, p. 3692-3702 11 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Novel transcriptional profile in wrist muscles from cerebral palsy patients

Smith, L. R., Pontén, E., Hedström, Y., Ward, S. R., Chambers, H. G., Subramaniam, S. & Lieber, R. L., Aug 27 2009, In : BMC Medical Genomics. 2, 44.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations
2007

The effects of force inhibition by sodium vanadate on cross-bridge binding, force redevelopment, and Ca2+ activation in cardiac muscle

Martyn, D. A., Smith, L., Kreutziger, K. L., Xu, S., Yu, L. C. & Regnier, M., Jun 2007, In : Biophysical Journal. 92, 12, p. 4379-4390 12 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations