• 6532 Citations
  • 41 h-Index
1989 …2021
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  • 10 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Microglia Medicine & Life Sciences
Brain Medicine & Life Sciences
Neurons Medicine & Life Sciences
Amyloid beta-Peptides Medicine & Life Sciences
Pyrones Medicine & Life Sciences

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Projects 1991 2021

UC DAVIS ALZHEIMERS DISEASE CENTER CORE

DeCarli, C., Mathis, C., Biegon, A., Eberling, J. L., Jagust, W. J., Lindeman, D., Weiler, P., Hinton, W. L., Mungas, D. M., Beckett, L. A., Carter, C. S., Haan, M. N., Ellis, W., Olichney, J. M. & Jin, L.

National Institutes of Health

9/30/916/30/21

Project: Research projectCenter Core Grants

Alzheimer Disease
Neuroimaging
Research
Antibody-Dependent Cell Cytotoxicity
Autopsy

The Microglial Kv1.3 Channel in Alzheimer's Disease

Wulff, H. & Jin, L.

National Institutes of Health

8/1/116/30/13

Project: Research projectExploratory/Developmental Grants

Microglia
Alzheimer Disease
Amyloid
Kv1.3 Potassium Channel
Voltage-Gated Potassium Channels

The role of astrocytes in Rett syndrome

Jin, L.

National Institutes of Health

1/1/1112/31/15

Project: Research projectResearch Project

Rett Syndrome
Astrocytes
Methyl-CpG-Binding Protein 2
Serine
Protein Deficiency

Identify Abeta Oligomer Inhibitors By Combinatorial Chemistry

Jin, L.

National Institutes of Health

9/1/088/31/11

Project: Research projectExploratory/Developmental Grants

Amyloid beta-Peptides
Alzheimer Disease
Ligands
Poisons
Dementia

Research Output 1989 2018

  • 6532 Citations
  • 41 h-Index
  • 116 Article
  • 2 Chapter
  • 1 Comment/debate
  • 1 Letter

A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta

Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.

Research output: Contribution to journalArticle

Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
1 Citations

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
4 Citations

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity

Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.

Research output: Contribution to journalArticle

Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation
4 Citations

K v 1.3 inhibition as a potential microglia-Targeted therapy for Alzheimer's disease: Preclinical proof of concept

Maezawa, I., Nguyen, H. M., Di Lucente, J., Jenkins, D. P., Singh, V., Hilt, S., Kim, K., Rangaraju, S., Levey, A. I., Wulff, H. & Jin, L-W., Feb 1 2018, In : Brain. 141, 2, p. 596-612 17 p.

Research output: Contribution to journalArticle

Microglia
Amyloid
Alzheimer Disease
Therapeutics
Transgenic Mice
2 Citations

Sex-specific genetic predictors of Alzheimer’s disease biomarkers

Alzheimer’S Disease Neuroimaging Initiative (Adni) & The Alzheimer Disease Genetics Consortium (Adgc), Jul 2 2018, (Accepted/In press) In : Acta Neuropathologica. p. 1-16 16 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Genome-Wide Association Study
Amyloid
Endophenotypes