• 2811 Citations
  • 29 h-Index
1976 …2020

Research output per year

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Research Output

  • 2811 Citations
  • 29 h-Index
  • 90 Article
  • 3 Chapter
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Article
2020

A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

Mouse Metabolic Phenotyping Center Energy Balance Working Group, May 2020, In : eLife. 9, p. 1-34 34 p., e53560.

Research output: Contribution to journalArticle

Open Access

Sex differences in response to short-term high fat diet in mice

Huang, K. P., Ronveaux, C. C., Knotts, T. A., Rutkowsky, J. R., Ramsey, J. J. & Raybould, H. E., Jul 1 2020, In : Physiology and Behavior. 221, 112894.

Research output: Contribution to journalArticle

1 Scopus citations

Sex-specific alterations in whole body energetics and voluntary activity in heterozygous R163C malignant hyperthermia-susceptible mice

Rutkowsky, J. M., Knotts, T. A., Allen, P. D., Pessah, I. N. & Ramsey, J. J., Jan 1 2020, (Accepted/In press) In : FASEB Journal.

Research output: Contribution to journalArticle

Open Access
2019

The Impact of Aging, Calorie Restriction and Dietary Fat on Autophagy Markers and Mitochondrial Ultrastructure and Dynamics in Mouse Skeletal Muscle

Gutiérrez-Casado, E., Khraiwesh, H., López-Domínguez, J. A., Montero-Guisado, J., López-Lluch, G., Navas, P., de Cabo, R., Ramsey, J. J., González-Reyes, J. A. & Villalba, J. M., May 16 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 6, p. 760-769 10 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A. A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., Imai, D. M., Griffey, S. M., Kim, K., Hagopian, K., McMackin, M. Z., Haj, F. G., Baar, K., Cortopassi, G. A., Ramsey, J. J. & Lopez-Dominguez, J. A., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

7 Scopus citations

Estimated heat production, blood parameters and mitochondrial DNA copy number of Nellore bulls (Bos indicus) with high and low residual feed intake

Baldassini, W. A., Ramsey, J. J., Branco, R. H., Bonilha, S. F. M., Chiaratti, M. R., Chaves, A. S. & Lanna, D. P. D., Nov 1 2018, In : Livestock Science. 217, p. 140-147 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome

Vogel Ciernia, A., Yasui, D. H., Pride, M. C., Durbin-Johnson, B., Noronha, A. B., Chang, A., Knotts, T. A., Rutkowsky, J. R., Ramsey, J. J., Crawley, J. & LaSalle, J. M., Dec 1 2018, In : Human Molecular Genetics. 27, 23, p. 4077-4093 17 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., Imai, D., Griffey, S. M., Kim, K., Hagopian, K., Haj, F., Baar, K., Cortopassi, G. A., Ramsey, J. J. & Lopez-Dominguez, J. A., Sep 5 2017, In : Cell Metabolism. 26, 3, p. 539-546.e5

Research output: Contribution to journalArticle

89 Scopus citations

Effects of obesity, energy restriction and neutering on the faecal microbiota of cats

Fischer, M. M., Kessler, A. M., Kieffer, D. A., Knotts, T. A., Kim, K., Wei, A., Ramsey, J. J. & Fascetti, A. J., Sep 29 2017, (Accepted/In press) In : British Journal of Nutrition. p. 1-12 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2 Scopus citations

The influence of Shc proteins and high-fat diet on energy metabolism of mice

Baldassini, W. A., Ramsey, J. J., Hagopian, K. & Lanna, D. P. D., Dec 1 2017, In : Cell Biochemistry and Function. 35, 8, p. 527-537 11 p.

Research output: Contribution to journalArticle

2016

Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice

Calvo-Rubio, M., Burón, M. I., López-Lluch, G., Navas, P., de Cabo, R., Ramsey, J. J., Villalba, J. M. & González-Reyes, J. A., Jun 1 2016, In : Aging Cell. 15, 3, p. 477-487 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lack of glucuronidation products of trans-resveratrol in plasma and urine of cats

Burnett, K., Puschner, B., Ramsey, J. J., Lin, Y., Wei, A. & Fascetti, A. J., 2016, (Accepted/In press) In : Journal of Animal Physiology and Animal Nutrition.

Research output: Contribution to journalArticle

1 Scopus citations
2 Scopus citations
1 Scopus citations

Omega-3 fatty acids partially revert the metabolic gene expression profile induced by long-term calorie restriction

López-Domínguez, J. A., Cánovas, Á., Medrano, J. F., Islas-Trejo, A., Kim, K., Taylor, S. L., Villalba, J. M., López-Lluch, G., Navas, P. & Ramsey, J. J., May 1 2016, In : Experimental Gerontology. 77, p. 29-37 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

p46Shc inhibits thiolase and lipid oxidation in mitochondria

Tomilov, A., Tomilova, N., Shan, Y., Hagopian, K., Bettaieb, A., Kim, K., Pelicci, P. G., Haj, F., Ramsey, J. J. & Cortopassi, G. A., Jun 10 2016, In : Journal of Biological Chemistry. 291, 24, p. 12575-12585 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice

López-Domínguez, J. A., Khraiwesh, H., González-Reyes, J. A., López-Lluch, G., Navas, P., Ramsey, J. J., De Cabo, R., Burón, M. I. & Villalba, J. M., Apr 1 2015, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 4, p. 399-409 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
8 Scopus citations

The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice

Villalba, J. M., López-Domínguez, J. A., Chen, Y., Khraiwesh, H., González-Reyes, J. A., del Río, L. F., Gutiérrez-Casado, E., del Río, M., Calvo-Rubio, M., Ariza, J., de Cabo, R., López-Lluch, G., Navas, P., Hagopian, K., Burón, M. I. & Ramsey, J. J., Oct 31 2015, In : Biogerontology. 16, 5, p. 655-670 16 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Early effects of neutering on energy expenditure in adult male cats

Wei, A., Fascetti, A. J., Kim, K., Lee, A., Graham, J. L., Havel, P. J. & Ramsey, J. J., Feb 26 2014, In : PLoS One. 9, 2, e89557.

Research output: Contribution to journalArticle

12 Scopus citations
6 Scopus citations

Mitochondria in health and disease

Magalhães, J., Venditti, P., Adhihetty, P. J., Ramsey, J. J. & Ascensão, A., 2014, In : Oxidative Medicine and Cellular Longevity. 2014, 814042.

Research output: Contribution to journalArticle

7 Scopus citations

Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats

Khraiwesh, H., López-Domínguez, J. A., Fernández del Río, L., Gutierrez-Casado, E., López-Lluch, G., Navas, P., de Cabo, R., Ramsey, J. J., Burón, M. I., Villalba, J. M. & González-Reyes, J. A., 2014, In : Experimental Gerontology. 56, p. 77-88 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Shc depletion stimulates brown fat activity in vivo and in vitro

Tomilov, A., Bettaieb, A., Kim, K., Sahdeo, S., Tomilova, N., Lam, A., Hagopian, K., Connell, M., Fong, J., Rowland, D., Griffey, S. M., Ramsey, J. J., Haj, F. & Cortopassi, G. A., Dec 1 2014, In : Aging Cell. 13, 6, p. 1049-1058 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice

López-Domínguez, J. A., Ramsey, J. J., Tran, D., Imai, D., Koehne, A., Laing, S. T., Griffey, S. M., Kim, K., Taylor, S. L., Hagopian, K., Villalba, J. M., López-Lluch, G., Navas, P. & McDonald, R. B., Nov 19 2014, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 10, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction

Chen, Y., Hagopian, K., Bibus, D., Villalba, J. M., López-Lluch, G., Navas, P., Kim, K. & Ramsey, J. J., 2014, In : Physiological Research. 63, 1, p. 57-71 15 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats

Khraiwesh, H., López-Domínguez, J. A., López-Lluch, G., Navas, P., De Cabo, R., Ramsey, J. J., Villalba, J. M. & González-Reyes, J. A., Sep 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 9, p. 1023-1034 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations

Hagopian, K., Soo Hoo, R., López-Domínguez, J. A. & Ramsey, J. J., Dec 5 2013, In : Life Sciences. 93, 24, p. 941-948 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorierestricted mice

López-Domínguez, J. A., Khraiwesh, H., González-Reyes, J. A., López-Lluch, G., Navas, P., Ramsey, J. J., De Cabo, R., Burón, M. I. & Villalba, J. M., Dec 2013, In : Age. 35, 6, p. 2027-2044 18 p.

Research output: Contribution to journalArticle

15 Scopus citations

The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction

Chen, Y., Hagopian, K., Bibus, D., Villalba, J. M., Opez-Lluch, G. L., Navas, P., Kim, K., McDonald, R. B. & Ramsey, J. J., Feb 2013, In : Bioscience Reports. 33, 1, p. 83-95 13 p., A9.

Research output: Contribution to journalArticle

23 Scopus citations
2012

Hepatic Src homology phosphatase 2 regulates energy balance in mice

Nagata, N., Matsuo, K., Bettaieb, A., Bakke, J., Matsuo, I., Graham, J., Xi, Y., Liu, S., Tomilov, A., Tomilova, N., Gray, S., Jung, D. Y., Ramsey, J. J., Kim, J. K., Cortopassi, G. A., Havel, P. J. & Haj, F., Jul 2012, In : Endocrinology. 153, 7, p. 3158-3169 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis

Hagopian, K., Tomilov, A., Tomilova, N., Kim, K., Taylor, S. L., Lam, A. K., Cortopassi, G. A., McDonald, R. B. & Ramsey, J. J., Dec 2012, In : Metabolism: Clinical and Experimental. 61, 12, p. 1703-1713 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The influence of acute, late-life calorie restriction on whole body energy metabolism in p66Shc(-/-) mice

Stern, J. H., Kim, K. & Ramsey, J. J., Jun 2012, In : Mechanisms of Ageing and Development. 133, 6, p. 414-420 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction

Chen, Y., Hagopian, K., McDonald, R. B., Bibus, D., López-Lluch, G., Villalba, J. M., Navas, P. & Ramsey, J. J., Nov 2012, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 67, 11, p. 1121-1131 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

The Influence of Shc Proteins and Aging on Whole Body Energy Expenditure and Substrate Utilization in Mice

Stern, J. H., Kim, K. & Ramsey, J. J., Nov 7 2012, In : PLoS One. 7, 11, e48790.

Research output: Contribution to journalArticle

4 Scopus citations

The p66 Shc knocked out mice are short lived under natural condition

Giorgio, M., Berry, A., Berniakovich, I., Poletaeva, I., Trinei, M., Stendardo, M., Hagopian, K., Ramsey, J. J., Cortopassi, G. A., Migliaccio, E., Nötzli, S., Amrein, I., Lipp, H. P., Cirulli, F. & Pelicci, P. G., Feb 2012, In : Aging Cell. 11, 1, p. 162-168 7 p.

Research output: Contribution to journalArticle

55 Scopus citations
2011

Caloric restriction influences hydrogen peroxide generation in mitochondrial sub-populations from mouse liver

Hagopian, K., Chen, Y., Simmons Domer, K., Soo Hoo, R., Bentley, T., McDonald, R. B. & Ramsey, J. J., 2011, In : Journal of Bioenergetics and Biomembranes. 43, 3, p. 227-236 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues

Parrado-Fernández, C., López-Lluch, G., Rodríguez-Bies, E., Santa-Cruz, S., Navas, P., Ramsey, J. J. & Villalba, J. M., Jun 15 2011, In : Free Radical Biology and Medicine. 50, 12, p. 1728-1736 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Effect of water content in a canned food on voluntary food intake and body weight in cats

Wei, A., Fascetti, A. J., Villaverde, C., Wong, R. K. & Ramsey, J. J., Jul 2011, In : American Journal of Veterinary Research. 72, 7, p. 918-923 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Influence of a high-protein diet on energy balance in obese cats allowed ad libitum access to food

Wei, A., Fascetti, A. J., Liu, K. J., Villaverde, C., Green, A. S., Manzanilla, E. G., Havel, P. J. & Ramsey, J. J., Jun 2011, In : Journal of Animal Physiology and Animal Nutrition. 95, 3, p. 359-367 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

The Shc locus regulates insulin signaling and adiposity in mammals

Tomilov, A., Ramsey, J. J., Hagopian, K., Giorgio, M., Kim, K., Lam, A., Migliaccio, E., Lloyd, K. C. K., Berniakovich, I., Prolla, T. A., Pelicci, P. & Cortopassi, G. A., Feb 2011, In : Aging Cell. 10, 1, p. 55-65 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
2010

Application of modular kinetic analysis to mitochondrial oxidative phosphorylation in skeletal muscle of birds exposed to acute heat stress

Kikusato, M., Ramsey, J. J., Amo, T. & Toyomizu, M., Jul 2010, In : FEBS Letters. 584, 14, p. 3143-3148 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Complex i-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice

Hagopian, K., Weber, K. L., Hwee, D. T., van Eenennaam, A. L., López-Lluch, G., Villalba, J. M., Burón, I., Navas, P., German, J. B., Watkins, S. M., Chen, Y., Wei, A., McDonald, R. B. & Ramsey, J. J., 2010, In : PLoS One. 5, 9, p. 1-11 11 p., e12696.

Research output: Contribution to journalArticle

41 Scopus citations

Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice

Tomilov, A., Bicocca, V., Schoenfeld, R. A., Giorgio, M., Migliaccio, E., Ramsey, J. J., Hagopian, K., Pelicci, P. G. & Cortopassi, G. A., 2010, In : Journal of Biological Chemistry. 285, 2, p. 1153-1165 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Honoring Clive McCay and 75 years of calorie restriction research

McDonald, R. B. & Ramsey, J. J., Jul 2010, In : Journal of Nutrition. 140, 7, p. 1205-1210 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
2009
8 Scopus citations

Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver

Hagopian, K., Ramsey, J. J. & Weindruch, R., 2009, In : Biogerontology. 10, 4, p. 471-479 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Differences in mitochondrial efficiency between lines of mice divergently selected for heat loss

McDonald, J. M., Ramsey, J. J., Miner, J. L. & Nielsen, M. K., Oct 2009, In : Journal of Animal Science. 87, 10, p. 3105-3113 9 p.

Research output: Contribution to journalArticle

17 Scopus citations