• 2561 Citations
  • 31 h-Index
1990 …2019

Research output per year

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Research Output

  • 2561 Citations
  • 31 h-Index
  • 43 Article
  • 3 Review article
2019

First-year seminars as a venue for course-based undergraduate research experiences: A preliminary report

Vater, A., Dahlhausen, K., Coil, D. A., Anderton, B. N., Wirawan, C. S., Caporale, N. & David Furlow, J., Aug 2019, In : Bioscene. 45, 2, p. 3-10 8 p.

Research output: Contribution to journalArticle

2018

RXR ligands modulate thyroid hormone signaling competence in young xenopus laevis tadpoles

Mengeling, B. J., Goodson, M. L. & Furlow, J., Jul 1 2018, In : Endocrinology. 159, 7, p. 2576-2595 20 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling

Mengeling, B. J., Wei, Y., Dobrawa, L. N., Streekstra, M., Louisse, J., Singh, V., Singh, L., Lein, P. J., Wulff, H., Murk, A. J. & Furlow, J., Sep 1 2017, In : Aquatic Toxicology. 190, p. 1-10 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Expanding the genetic toolkit in Xenopus: Approaches and opportunities for human disease modeling

Tandon, P., Conlon, F., Furlow, J. & Horb, M. E., Jun 15 2017, In : Developmental Biology. 426, 2, p. 325-335 11 p.

Research output: Contribution to journalReview article

46 Scopus citations
2016

Chasing the Elusive Benzofuran Impurity of the THR Antagonist NH-3: Synthesis, Isotope Labeling, and Biological Activity

Singh, L., Pressly, B., Mengeling, B. J., Fettinger, J. C., Furlow, J., Lein, P. J., Wulff, H. & Singh, V., Mar 4 2016, In : Journal of Organic Chemistry. 81, 5, p. 1870-1876 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulation of vernal migration in Gambel's white-crowned sparrows: Role of thyroxine and triiodothyronine

Pérez, J. H., Furlow, J., Wingfield, J. C. & Ramenofsky, M., Aug 1 2016, In : Hormones and Behavior. 84, p. 50-56 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Trialkyltin rexinoid-X receptor agonists selectively potentiate thyroid hormone induced programs of xenopus laevis metamorphosis

Mengeling, B. J., Murk, A. J. & Furlow, J., Jul 1 2016, In : Endocrinology. 157, 7, p. 2712-2723 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Glucocorticoids and skeletal muscle

Bodine, S. C. & Furlow, J., 2015, In : Advances in Experimental Medicine and Biology. 872, p. 145-176 32 p.

Research output: Contribution to journalArticle

47 Scopus citations
6 Scopus citations
2014

Identification of thyroid hormone receptor active compounds using a quantitative high-throughput screening platform

Freitas, J., Miller, N., Mengeling, B. J., Xia, M., Huang, R., Houck, K., Rietjens, I. M. C. M., Furlow, J. & Murk, A. J., Jan 1 2014, In : Current Chemical Genomics and Translational Medicine. 8, 1, p. 36-46 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Altered gene expression patterns in muscle ring finger 1 null mice during denervation- and dexamethasone-induced muscle atrophy

Furlow, J., Watson, M. L., Waddell, D. S., Neff, E. S., Baehr, L. M., Ross, A. P. & Bodine, S. C., Dec 1 2013, In : Physiological Genomics. 45, 23, p. 1168-1185 18 p.

Research output: Contribution to journalArticle

29 Scopus citations

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Murk, A. T. J., Rijntjes, E., Blaauboer, B. J., Clewell, R., Crofton, K. M., Dingemans, M. M. L., Furlow, J., Kavlock, R., Köhrle, J., Opitz, R., Traas, T., Visser, T. J., Xia, M. & Gutleb, A. C., Jun 1 2013, In : Toxicology in Vitro. 27, 4, p. 1320-1346 27 p.

Research output: Contribution to journalReview article

114 Scopus citations
2012

A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure

Watson, M. L., Baehr, L. M., Reichardt, H. M., Tuckermann, J. P., Bodine, S. C. & Furlow, J., May 15 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 10

Research output: Contribution to journalArticle

63 Scopus citations

A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting

Files, D. C., D'Alessio, F. R., Johnston, L. F., Kesari, P., Aggarwal, N. R., Garibaldi, B. T., Mock, J. R., Simmers, J. L., DeGorordo, A., Murdoch, J., Willis, M. S., Patterson, C., Tankersley, C. G., Messi, M. L., Liu, C., Delbono, O., Furlow, J., Bodine, S. C., Cohn, R. D., King, L. S. & 1 others, Crow, M. T., Apr 15 2012, In : American Journal of Respiratory and Critical Care Medicine. 185, 8, p. 825-834 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

Gomes, A. V., Waddell, D. S., Siu, R., Stein, M., Dewey, S., Furlow, J. & Bodine, S. C., Jul 2012, In : FASEB Journal. 26, 7, p. 2986-2999 14 p.

Research output: Contribution to journalArticle

63 Scopus citations
2011

Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay

Freitas, J., Cano, P., Craig-Veit, C., Goodson, M. L., Furlow, J. & Murk, A. J., Feb 1 2011, In : Toxicology in Vitro. 25, 1, p. 257-266 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Muscle sparing in muscle RING finger 1 null mice: Response to synthetic glucocorticoids

Baehr, L. M., Furlow, J. & Bodine, S. C., Oct 2011, In : Journal of Physiology. 589, 19, p. 4759-4776 18 p.

Research output: Contribution to journalArticle

108 Scopus citations
2009

Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer

Johnsen, S. A., Güngör, C., Prenzel, T., Riethdorf, S., Riethdorf, L., Taniguchi-Ishigaki, N., Rau, T., Tursun, B., Furlow, J., Sauter, G., Scheffner, M., Pantel, K., Gannon, F. & Bach, I., Jan 1 2009, In : Cancer Research. 69, 1, p. 128-136 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis

Denver, R. J., Hu, F., Scanlan, T. S. & Furlow, J., Feb 1 2009, In : Developmental Biology. 326, 1, p. 155-168 14 p.

Research output: Contribution to journalArticle

68 Scopus citations
2008

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

Waddell, D. S., Baehr, L. M., Van Den Brandt, J., Johnsen, S. A., Reichardt, H. M., Furlow, J. & Bodine, S. C., Oct 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 4

Research output: Contribution to journalArticle

214 Scopus citations
2007

Thyroid hormone receptor isoform selectivity of thyroid hormone disrupting compounds quantified with an in vitro reporter gene assay

Schriks, M., Roessig, J. M., Murk, A. J. & Furlow, J., May 1 2007, In : Environmental Toxicology and Pharmacology. 23, 3, p. 302-307 6 p.

Research output: Contribution to journalArticle

43 Scopus citations
2006

A developmental switch induced by thyroid hormone: Xenopus laevis metamorphosis

Furlow, J. & Neff, E. S., Mar 1 2006, In : Trends in Endocrinology and Metabolism. 17, 2, p. 38-45 8 p.

Research output: Contribution to journalReview article

95 Scopus citations

Disruption of thyroid hormone-mediated Xenopus laevis tadpole tail tip regression by hexabromocyclododecane (HBCD) and 2,2′,3,3′,4,4′,5,5′,6-nona brominated diphenyl ether (BDE206)

Schriks, M., Zvinavashe, E., Furlow, J. & Murk, A. J., Dec 1 2006, In : Chemosphere. 65, 10, p. 1904-1908 5 p.

Research output: Contribution to journalArticle

30 Scopus citations
2 Scopus citations
2004

Induction of Larval tissue resorption in Xenopus laevis tadpoles by the thyroid hormone receptor agonist GC-1

Furlow, J., Yang, H. Y., Hsu, M., Lim, W., Ermio, D. J., Chiellini, G. & Scanlan, T. S., Jun 18 2004, In : Journal of Biological Chemistry. 279, 25, p. 26555-26562 8 p.

Research output: Contribution to journalArticle

51 Scopus citations
22 Scopus citations

The mouse muscle creatine kinase promoter faithfully drives reporter gene expression in transgenic Xenopus laevis

Lim, W., Neff, E. S. & Furlow, J., Oct 1 2004, In : Physiological Genomics. 18, p. 79-86 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2002

A thyroid hormone antagonist that inhibits thyroid hormone action in vivo

Lim, W., Nguyen, N. H., Yang, H. Y., Scanlan, T. S. & Furlow, J., Sep 20 2002, In : Journal of Biological Chemistry. 277, 38, p. 35664-35670 7 p.

Research output: Contribution to journalArticle

82 Scopus citations

Ribozyme suppression of endogenous thyroid hormone receptor activity in Xenopus laevis cells

Lim, W. & Furlow, J., Aug 1 2002, In : Nucleic Acids Research. 30, 15, p. 3490-3496 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

The transcription factor basic transcription element-binding protein 1 is a direct thyroid hormone response gene in the frog Xenopus laevis

Furlow, J. & Kanamori, A., Sep 1 2002, In : Endocrinology. 143, 9, p. 3295-3305 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
2001

Selective modulation of thyroid hormone receptor action

Baxter, J. D., Dillmann, W. H., West, B. L., Huber, R., Furlow, J., Fletterick, R. J., Webb, P., Apriletti, J. W. & Scanlan, T. S., Jun 18 2001, In : Journal of Steroid Biochemistry and Molecular Biology. 76, 1-5, p. 31-42 12 p.

Research output: Contribution to journalArticle

104 Scopus citations
1999

In vitro and in vivo analysis of the regulation of a transcription factor gene by thyroid hormone during Xenopus laevis metamorphosis

Furlow, J. & Brown, D. D., Jan 1 1999, In : Molecular Endocrinology. 13, 12, p. 2076-2089 14 p.

Research output: Contribution to journalArticle

72 Scopus citations
1997

A set of novel tadpole specific genes expressed only in the epidermis are down-regulated by thyroid hormone during Xenopus laevis metamorphosis

Furlow, J., Berry, D. L., Wang, Z. & Brown, D. D., Feb 15 1997, In : Developmental Biology. 182, 2, p. 284-298 15 p.

Research output: Contribution to journalArticle

60 Scopus citations
1996

The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis

Brown, D. D., Wang, Z., Furlow, J., Kanamori, A., Schwartzman, R. A., Remo, B. F. & Pinder, A., Mar 5 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 5, p. 1924-1929 6 p.

Research output: Contribution to journalArticle

212 Scopus citations
1995

Amphibian metamorphosis: A complex program of gene expression changes controlled by the thyroid hormone

Brown, D. D., Wang, Z., Kanamori, A., Eliceiri, B., Furlow, J. & Schwartzman, R., Dec 1 1995, In : Recent Progress in Hormone Research. 50, 1, p. 309-315 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Estrogen Receptor Binding to DNA: Affinity for Nonpalindromic Elements from the Rat Prolactin Gene

Murdoch, F. E., Byrne, L. M., Ariazi, E. A., Furlow, J., Meier, D. A. & Gorski, J., Jan 1 1995, In : Biochemistry. 34, 28, p. 9144-9150 7 p.

Research output: Contribution to journalArticle

40 Scopus citations
1993

High affinity binding of the estrogen receptor to a DNA response element does not require homodimer formation or estrogen

Furlow, J., Murdoch, F. E. & Gorski, J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 17, p. 12519-12525 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Involvement of the coding sequence for the estrogen receptor gene in autologous ligand-dependent down-regulation

Kaneko, K. J., Furlow, J. & Gorski, J., Jan 1 1993, In : Molecular Endocrinology. 7, 7, p. 879-888 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Perturbations in the model of estrogen receptor regulation of gene expression

Gorski, J., Furlow, J., Murdoch, F. E., Fritsch, M., Kaneko, K., Ying, C. & Malayer, J. R., Jan 5 1993, In : Biology of Reproduction. 48, 1, p. 8-14 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
1992

A Ligand-Induced Conformational Change in the Estrogen Receptor Is Localized in the Steroid Binding Domain

Fritsch, M., Leary, C. M., Furlow, J., Gorski, J., Ahrens, H., Mueller, G. C. & Schuh, T. J., Feb 1 1992, In : Biochemistry. 31, 23, p. 5303-5311 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Immunodetection of estrogen receptors in fetal and neonatal male mouse reproductive tracts

Greco, T. L., Furlow, J., Duello, T. M. & Gorski, J., Jan 1 1992, In : Endocrinology. 130, 1, p. 421-429 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

Overproduction of full-length and truncated human estrogen receptors in Escherichia coli.

Ahrens, H., Schuh, T. J., Rainish, B. L., Furlow, J., Gorski, J. & Mueller, G. C., Jun 1 1992, In : Receptor. 2, 2, p. 77-92 16 p.

Research output: Contribution to journalArticle

14 Scopus citations
1991

An estrogen-responsive element mediates the transcriptional regulation of calbindin D-9K gene in rat uterus

Darwish, H., Krisinger, J., Furlow, J., Smith, C., Murdoch, F. E. & DeLuca, H. F., Jan 5 1991, In : Journal of Biological Chemistry. 266, 1, p. 551-558 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

Immunodetection of estrogen receptors in fetal and neonatal female mouse reproductive tracts

Greco, T. L., Furlow, J., Duello, T. M. & Gorski, J., Jan 1 1991, In : Endocrinology. 129, 3, p. 1326-1332 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
1990

Antisera to a synthetic peptide recognize native and denatured rat estrogen receptors

Furlow, J., Ahrens, H., Mueller, G. C. & Gorski, J., Jan 1 1990, In : Endocrinology. 127, 3, p. 1028-1032 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Estrogen Receptor Binding to a DNA Response Element in Vitro Is Not Dependent upon Estradiol

Murdoch, F. E., Furlow, J., Grunwald, K. A. A., Gorski, J. & Meier, D. A., Sep 1 1990, In : Biochemistry. 29, 36, p. 8377-8385 9 p.

Research output: Contribution to journalArticle

91 Scopus citations