• 5551 Citations
  • 39 h-Index
1984 …2021
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Fingerprint Dive into the research topics where John C Rutledge is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Lipolysis Medicine & Life Sciences
Lipoproteins Medicine & Life Sciences
Triglycerides Medicine & Life Sciences
Permeability Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
LDL Lipoproteins Medicine & Life Sciences
Atherosclerosis Medicine & Life Sciences
Inflammation Medicine & Life Sciences

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Projects 1990 2021

High Fat Diet
Vascular Dementia
Alzheimer Disease
VLDL Lipoproteins
Blood-Brain Barrier

General Clinical Research Center

Dronkers, N., Yonelinas, A., Wolfe, B., van Loan, M., Asmuth, D., Chang, D., Sigvardt, K., Simon, S. I., Yund, E., Devaraj, S., Reed, B., Robertson, L. C., Gandara, D., Scudder, S., Glatter, K., Jacoby, R., Stebbins, C., Woods, D., Dandekar, S., Tuscano, J., Fu-Tong, L., Hagerman, R., Stern, J., Tanaka, M., Kravitz, R., De Vere White, R. W., Wexler, J., Baynes, K., Davies, A., Miller, J. W., Halsted, C. H., Chew, H., Hagerman, P., Gold, E., King, J., Pollard, R., Schenker, M., Siegel, D., Swick, D., Karakas, S., Pomeroy, C., Silva, J., derick, L., Wilsey, B. L., Wheelock, V., Havel, P. J., Muizelaar, J. P., Jialal, I., Keim, N. L., Rutledge, J. C., Berglund, L., Decarli, C., Schenker, M. B., Simon, S. I. & Swick, D.

National Institutes of Health


Project: Research project

Research Personnel
Delivery of Health Care
Apolipoprotein E3
Cell Communication
Apolipoprotein E4
Endothelial Cells

Research Output 1984 2019

  • 5551 Citations
  • 39 h-Index
  • 124 Article
  • 2 Review article
  • 1 Chapter

Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury

Nyunt, T., Britton, M., Wanichthanarak, K., Budamagunta, M., Voss, J. C., Wilson, D. W., Rutledge, J. C. & Aung, H. H., Nov 1 2019, In : Free Radical Biology and Medicine. 143, p. 25-46 22 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Oxidative stress
Brain Injuries

The Western Diet Regulates Hippocampal Microvascular Gene Expression: An Integrated Genomic Analyses in Female Mice

Nuthikattu, S., Milenkovic, D., Rutledge, J. & Villablanca, A., Dec 1 2019, In : Scientific reports. 9, 1, 19058.

Research output: Contribution to journalArticle

Open Access
Gene Expression
Untranslated RNA
T Cell Transcription Factor 1
Small Nucleolar RNA

Chronic consumption of a western diet modifies the DNA methylation profile in the frontal cortex of mice

Yokoyama, A. S., Dunaway, K., Rutkowsky, J., Rutledge, J. C. & Milenkovic, D., Feb 1 2018, In : Food and Function. 9, 2, p. 1187-1198 12 p.

Research output: Contribution to journalArticle

Frontal Lobe
DNA methylation
DNA Methylation
1 Citation (Scopus)

Inhibition of perilipin 2 expression reduces pro-inflammatory gene expression and increases lipid droplet size

Norman, J. E., Aung, H. H., Wilson, D. W. & Rutledge, J. C., Dec 13 2018, In : Food & function. 9, 12, p. 6245-6256 12 p.

Research output: Contribution to journalArticle

droplet size
5 Citations (Scopus)

Reduced cognitive function, increased bloodbrain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr-/-And C57BL/6 mice fed a western diet

Rutkowsky, J. M., Lee, L. L., Puchowicz, M., Golub, M. S., Befroy, D. E., Wilson, D. W., Anderson, S., Cline, G., Bini, J., Borkowski, K., Knotts, T. A. & Rutledge, J. C., Feb 1 2018, In : PLoS One. 13, 2, e0191909.

Research output: Contribution to journalArticle

blood-brain barrier
Inbred C57BL Mouse