• 2070 Citations
  • 25 h-Index
19952019
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  • 2 Similar Profiles
Fluorescence Resonance Energy Transfer Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Capsaicin Medicine & Life Sciences
Transient Receptor Potential Channels Medicine & Life Sciences
Hot Temperature Medicine & Life Sciences
Shaker Superfamily of Potassium Channels Medicine & Life Sciences
Chemical activation Chemical Compounds
Cyclic Nucleotide-Gated Cation Channels Medicine & Life Sciences

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Projects 1997 2016

Cyclic Nucleotide-Gated Cation Channels
Fluorescence
Color Vision Defects
Fluorometry
Retinal Degeneration
Hot Temperature
Pain
Fluorometry
Capsaicin
Protein Binding

Research Output 1995 2019

  • 2070 Citations
  • 25 h-Index
  • 59 Article
  • 1 Chapter
1 Citation (Scopus)

Gain-of-Function Mutations in TRPM4 Activation Gate Cause Progressive Symmetric Erythrokeratodermia

Wang, H., Xu, Z., Lee, B. H., Vu, S., Hu, L., Lee, M., Bu, D., Cao, X., Hwang, S. T., Yang, Y., Zheng, J. & Lin, Z., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Erythrokeratodermia Variabilis
Skin
Chemical activation
Mutation
Transient Receptor Potential Channels
1 Citation (Scopus)

Molecular mechanism of the tree shrew’s insensitivity to spiciness

Han, Y., Li, B., Yin, T. T., Xu, C., Ombati, R., Luo, L., Xia, Y., Xu, L., Zheng, J., Zhang, Y., Yang, F., Wang, G. D., Yang, S. & Lai, R., Jul 12 2018, In : PLoS Biology. 16, 7, e2004921.

Research output: Contribution to journalArticle

Scandentia
Tupaiidae
Mammals
Capsaicin
Nutrition
3 Citations (Scopus)

The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel

Yang, F., Xiao, X., Lee, B. H., Vu, S., Yang, W., Yarov-Yarovoy, V. & Zheng, J., Dec 1 2018, In : Nature Communications. 9, 1, 2879.

Research output: Contribution to journalArticle

Capsaicin
Ion Channels
Chemical activation
activation
Structural Models
10 Citations (Scopus)

A bimodal activation mechanism underlies scorpion toxin-induced pain

Yang, S., Yang, F., Zhang, B., Lee, B. H., Li, B., Luo, L., Zheng, J. & Lai, R., Jan 1 2017, In : Science advances. 3, 8, 1700810.

Research output: Contribution to journalArticle

Scorpions
Protons
Bites and Stings
Pain
Voltage-Gated Potassium Channels
23 Citations (Scopus)

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

Yang, F. & Zheng, J., Jan 2 2017, (Accepted/In press) In : Protein and Cell. p. 1-9 9 p.

Research output: Contribution to journalArticle

Capsaicin
Chemical activation
Cryoelectron Microscopy
Capsicum
Mutagenesis