• 4658 Citations
  • 38 h-Index
1965 …2019
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Fingerprint Dive into the research topics where Jerold A Last is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Ozone Medicine & Life Sciences
Lung Medicine & Life Sciences
Collagen Medicine & Life Sciences
Rats Chemical Compounds
Aerosols Medicine & Life Sciences
Pulmonary Fibrosis Medicine & Life Sciences
Animals Chemical Compounds
Nitrogen Dioxide Medicine & Life Sciences

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Projects 1978 2013

toxicology
public health
technology transfer
immunoassay
drinking water

MECHANISMS OF OXIDANT INDUCED LYMPHOCYTE REGULATION

Last, J. A., Schenker, M. B., Pinkerton, K. E., Hammock, B. D., Buckpitt, A. R., Gold, E. B., Rice, R. H., Denison, M. S., Pessah, I. N., Krieger, J., Vulliet, P. R., Plopper, C. G., Lasley, B., Reen, W., Wilson, B., Matsumura, F., Wu, R. & Plopper, C.

National Institutes of Health

9/30/923/31/09

Project: Research project

Research Personnel
Research
Students
Genomics
Agrochemicals
Collagen
Lung
Hydroxylation
Tendons
Animal Models

PULMONARY EFFECTS OF ENVIRONMENTAL OXIDANT POLLUTANTS

Pinkerton, K. E., Last, J. A., Gershwin, L. J., Schelegle, E. S., Wu, R., Hyde, D. M., Goldstein, E., Tyler, W., Dungworth, D., Witschi, H., Joad, J., Plopper, C. & Plopper, C.

National Institutes of Health

9/30/784/30/12

Project: Research project

Ozone
Asthma
Lung
Air Pollutants
Oxidants

Research Output 1965 2019

  • 4658 Citations
  • 38 h-Index
  • 204 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Review article

Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression

Yang, D. C., Li, J. M., Xu, J., Oldham, J., Phan, S. H., Last, J. A., Wu, R. & Chen, C. H., Dec 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14354-14369 16 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Fibroblasts
Fibrosis
Chemical activation
Networks (circuits)

Farnesyltransferase inhibition exacerbates eosinophilic inflammation and airway hyperreactivity in mice with experimental asthma: The complex roles of ras GTPase and farnesylpyrophosphate in type 2 allergic inflammation

Bratt, J. M., Chang, K. Y., Rabowsky, M., Franzi, L. M., Ott, S. P., Filosto, S., Goldkorn, T., Arif, M., Last, J. A., Kenyon, N. & Zeki, A., Jun 1 2018, In : Journal of Immunology. 200, 11, p. 3840-3856 17 p.

Research output: Contribution to journalArticle

Farnesyltranstransferase
ras Proteins
Asthma
Inflammation
Prenylation
1 Citation (Scopus)

Effects of positive end-expiratory pressure and recruitment maneuvers in a ventilator-induced injury mouse model

Cagle, L. A., Franzi, L. M., Linderholm, A. L., Last, J. A., Adams, J. Y., Harper, R. W. & Kenyon, N., Nov 1 2017, In : PLoS One. 12, 11, e0187419.

Research output: Contribution to journalArticle

ventilators
Ventilator-Induced Lung Injury
Positive-Pressure Respiration
Tidal Volume
Mechanical Ventilators
3 Citations (Scopus)
Butorphanol
Dexmedetomidine
Anesthesia
Urethral Obstruction
Injections
3 Citations (Scopus)

Lung toxicity in mice of airborne particulate matter from a modern layer hen facility containing Proposition 2-compliant animal caging

Franzi, L. M., Linderholm, A. L., Rabowsky, M. & Last, J. A., 2017, In : Toxicology and Industrial Health. 33, 3, p. 211-221 11 p.

Research output: Contribution to journalArticle

Particulate Matter
Toxicity
Animals
Lung
Air